hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05029
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SYNM | Synemin (Desmuslin) | UniProt NCBI |
| DNAJB1 | DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1) | UniProt NCBI |
| ARHGAP45 | Rho GTPase-activating protein 45 [Cleaved into: Minor histocompatibility antigen HA-1 (mHag HA-1)] | UniProt NCBI |
| GABARAPL2 | Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein) | UniProt NCBI |
| DNAJB4 | DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein) | UniProt NCBI |
| DNAJB5 | DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40) | UniProt NCBI |
| BAG2 | BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0051087 | 0.00140301959916 | 0.571428571429 | DNAJB1 BAG2 DNAJB4 DNAJB5 | chaperone binding |
| GO:0051085 | 0.00560674176034 | 0.428571428571 | DNAJB1 DNAJB4 DNAJB5 | chaperone cofactor-dependent protein refolding |
| GO:0051084 | 0.0103609118753 | 0.428571428571 | DNAJB1 DNAJB4 DNAJB5 | 'de novo' posttranslational protein folding |
| GO:0006458 | 0.0156741996846 | 0.428571428571 | DNAJB1 DNAJB4 DNAJB5 | 'de novo' protein folding |
| GO:0060590 | 0.0172381420268 | 0.428571428571 | DNAJB1 BAG2 DNAJB4 | ATPase regulator activity |
| GO:0006457 | 0.0328154405385 | 0.571428571429 | DNAJB1 BAG2 DNAJB4 DNAJB5 | protein folding |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DNAJB4 | DNAJB1 | 0.994 | 0.919 | hein_WMM bioplex (DNAJB1,DNAJB4) bioplex_WMM boldt gupta_WMM fraction boldt_WMM |
| DNAJB4 | DNAJB5 | 0.337 | 0.526 | bioplex (DNAJB4) bioplex_WMM boldt_WMM |
| DNAJB4 | SYNM | 0.215 | 0.464 | bioplex (DNAJB4) bioplex_WMM |
| DNAJB1 | DNAJB5 | 0.053 | 0.301 | bioplex (DNAJB1) bioplex_WMM boldt_WMM |
| DNAJB1 | BAG2 | 0.022 | 0.21 | hein_WMM bioplex (DNAJB1) bioplex_WMM boldt hein (BAG2) gupta_WMM boldt_WMM |
| DNAJB4 | ARHGAP45 | 0.022 | 0.207 | fraction |
| DNAJB1 | GABARAPL2 | 0.022 | 0.208 | bioplex_WMM fraction |
| DNAJB4 | BAG2 | 0.02 | 0.184 | hein_WMM bioplex (DNAJB4) bioplex_WMM boldt hein (BAG2) boldt_WMM |
| DNAJB1 | SYNM | 0.008 | 0.031 | bioplex_WMM gupta_WMM WMM_only treiber_WMM |
| SYNM | DNAJB5 | 0.008 | 0.01 | bioplex_WMM WMM_only |
| BAG2 | SYNM | 0.007 | 0.0 | bioplex_WMM gupta_WMM WMM_only |
| BAG2 | GABARAPL2 | 0.007 | 0.003 | bioplex_WMM WMM_only boldt_WMM |
| DNAJB4 | GABARAPL2 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| BAG2 | DNAJB5 | 0.006 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05029 has an average edge precision of 0.219 which is ranked 5871 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SYNM | HuMAP2_01919 HuMAP2_04023 HuMAP2_05029 HuMAP2_05229 HuMAP2_05239 |
| DNAJB1 | HuMAP2_00228 HuMAP2_01919 HuMAP2_05029 HuMAP2_05239 |
| ARHGAP45 | HuMAP2_01919 HuMAP2_05029 |
| GABARAPL2 | HuMAP2_01919 HuMAP2_05029 HuMAP2_05219 |
| DNAJB4 | HuMAP2_00228 HuMAP2_01919 HuMAP2_05029 HuMAP2_05239 |
| DNAJB5 | HuMAP2_01919 HuMAP2_02901 HuMAP2_05029 HuMAP2_05239 |
| BAG2 | HuMAP2_00457 HuMAP2_02091 HuMAP2_02851 HuMAP2_05029 |