hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05056
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PDE4DIP | Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein) | UniProt NCBI |
| AKAP9 | A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao) | UniProt NCBI |
| NPPA | Natriuretic peptides A (CDD-ANF) (Cardiodilatin) (CDD) (Cardiodilatin-related peptide) (CDP) (Prepronatriodilatin) [Cleaved into: Atrial natriuretic factor (ANF) (Atrial natriuretic peptide) (ANP)] | UniProt NCBI |
| TMEM63C | Calcium permeable stress-gated cation channel 1 (Transmembrane protein 63C) | UniProt NCBI |
| A2ML1 | Alpha-2-macroglobulin-like protein 1 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9) | UniProt NCBI |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2) (Duranin) | UniProt NCBI |
| PRKACG | cAMP-dependent protein kinase catalytic subunit gamma (PKA C-gamma) (EC 2.7.11.11) | UniProt NCBI |
| PM20D1 | N-fatty-acyl-amino acid synthase/hydrolase PM20D1 (EC 3.5.1.-) (EC 4.3.-.-) (Peptidase M20 domain-containing protein 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04923 | 0.0113532598614 | 0.25 | PRKACG NPPA | Regulation of lipolysis in adipocytes |
| WP:WP4008 | 0.0114106486825 | 0.25 | NPPA AKAP9 | NO/cGMP/PKG mediated Neuroprotection |
| KEGG:04924 | 0.0164978688692 | 0.25 | PRKACG NPPA | Renin secretion |
| KEGG:04925 | 0.0454007036402 | 0.25 | PRKACG NPPA | Aldosterone synthesis and secretion |
| WP:WP35 | 0.0467166389275 | 0.25 | PRKACG AKAP9 | G Protein Signaling Pathways |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| 100134230 | PDE4DIP | 0.992 | 0.913 | bioplex (PDE4DIP) |
| PM20D1 | NPPA | 0.492 | 0.621 | bioplex (NPPA) bioplex_WMM |
| PM20D1 | PDE4DIP | 0.409 | 0.569 | bioplex (PDE4DIP) |
| AKAP9 | PDE4DIP | 0.098 | 0.357 | bioplex (PDE4DIP) bioplex_WMM |
| TMEM63C | NPPA | 0.06 | 0.335 | bioplex (NPPA) bioplex_WMM |
| L2HGDH | A2ML1 | 0.056 | 0.313 | bioplex (L2HGDH) bioplex_WMM treiber_WMM |
| PRKACG | 100134230 | 0.055 | 0.309 | bioplex (PRKACG) bioplex_WMM |
| A2ML1 | PDE4DIP | 0.048 | 0.296 | bioplex (PDE4DIP) |
| NPPA | A2ML1 | 0.034 | 0.261 | bioplex (NPPA) bioplex_WMM |
| AKAP9 | PRKACG | 0.026 | 0.224 | bioplex (PRKACG) bioplex_WMM |
| AKAP9 | 100134230 | 0.013 | 0.143 | bioplex_WMM WMM_only |
| PM20D1 | A2ML1 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| TMEM63C | PM20D1 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| PM20D1 | 100134230 | 0.008 | 0.059 | bioplex_WMM WMM_only |
| TMEM63C | A2ML1 | 0.008 | 0.039 | bioplex_WMM WMM_only |
| PM20D1 | AKAP9 | 0.008 | 0.024 | bioplex_WMM WMM_only |
| 100134230 | A2ML1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| PRKACG | PDE4DIP | 0.007 | 0.006 | bioplex_WMM WMM_only |
| AKAP9 | A2ML1 | 0.007 | 0.0 | bioplex_WMM WMM_only |
| PRKACG | L2HGDH | 0.007 | 0.003 | bioplex_WMM WMM_only |
| AKAP9 | L2HGDH | 0.007 | 0.003 | bioplex_WMM WMM_only |
| 100134230 | L2HGDH | 0.007 | 0.001 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05056 has an average edge precision of 0.212 which is ranked 5989 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PDE4DIP | HuMAP2_02402 HuMAP2_05056 |
| AKAP9 | HuMAP2_01784 HuMAP2_01832 HuMAP2_03596 HuMAP2_04684 HuMAP2_05056 |
| NPPA | HuMAP2_01110 HuMAP2_02402 HuMAP2_05056 |
| TMEM63C | HuMAP2_01110 HuMAP2_05056 |
| A2ML1 | HuMAP2_02402 HuMAP2_05056 |
| L2HGDH | HuMAP2_02402 HuMAP2_05056 |
| PRKACG | HuMAP2_01784 HuMAP2_01832 HuMAP2_02640 HuMAP2_04684 HuMAP2_05056 |
| PM20D1 | HuMAP2_01110 HuMAP2_02402 HuMAP2_05056 |