hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05059
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SETD2 | Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.43) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (Protein-lysine N-methyltransferase SETD2) (EC 2.1.1.-) (SET domain-containing protein 2) (hSET2) (p231HBP) | UniProt NCBI |
| SCAF8 | SR-related and CTD-associated factor 8 (CDC5L complex-associated protein 7) (RNA-binding motif protein 16) | UniProt NCBI |
| CCNG1 | Cyclin-G1 (Cyclin-G) | UniProt NCBI |
| NUCKS1 | Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (P1) | UniProt NCBI |
| WDR33 | pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein of 146 kDa) | UniProt NCBI |
| CPSF4L | Putative cleavage and polyadenylation specificity factor subunit 4-like protein | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0005849 | 0.00175581235783 | 0.5 | WDR33 CPSF4L SCAF8 | mRNA cleavage factor complex |
| HPA:035010_13 | 0.0300139609548 | 0.5 | WDR33 CCNG1 NUCKS1 | placenta; decidual cells[Supported,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CPSF4L | CCNG1 | 0.236 | 0.468 | bioplex (CPSF4L) bioplex_WMM |
| WDR33 | CPSF4L | 0.035 | 0.263 | bioplex (CPSF4L) bioplex_WMM |
| WDR33 | NUCKS1 | 0.023 | 0.208 | youn_WMM gupta_WMM fraction |
| WDR33 | SETD2 | 0.023 | 0.209 | bioplex_WMM youn_WMM fraction |
| WDR33 | SCAF8 | 0.022 | 0.199 | bioplex_WMM youn_WMM fraction |
| WDR33 | CCNG1 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| SETD2 | NUCKS1 | 0.007 | 0.009 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| SCAF8 | NUCKS1 | 0.007 | 0.006 | youn_WMM gupta_WMM WMM_only |
| SCAF8 | SETD2 | 0.007 | 0.006 | bioplex_WMM youn_WMM WMM_only |
| CCNG1 | NUCKS1 | 0.005 | 0.009 | bioplex (CCNG1) |
Images
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Complex HuMAP2_05059 has an average edge precision of 0.146 which is ranked 6730 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SETD2 | HuMAP2_00374 HuMAP2_03898 HuMAP2_05059 HuMAP2_05568 |
| SCAF8 | HuMAP2_00374 HuMAP2_00529 HuMAP2_05059 HuMAP2_05881 |
| CCNG1 | HuMAP2_01181 HuMAP2_05059 |
| NUCKS1 | HuMAP2_02806 HuMAP2_05059 |
| WDR33 | HuMAP2_00220 HuMAP2_00374 HuMAP2_05059 HuMAP2_06540 |
| CPSF4L | HuMAP2_01181 HuMAP2_05059 |