hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05061
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IL36RN | Interleukin-36 receptor antagonist protein (IL-36Ra) (FIL1 delta) (IL-1-related protein 3) (IL-1RP3) (Interleukin-1 HY1) (IL-1HY1) (Interleukin-1 delta) (IL-1 delta) (Interleukin-1 family member 5) (IL-1F5) (Interleukin-1 receptor antagonist homolog 1) (IL-1ra homolog 1) (Interleukin-1-like protein 1) (IL-1L1) | UniProt NCBI |
| DDX19B | ATP-dependent RNA helicase DDX19B (EC 3.6.4.13) (DEAD box RNA helicase DEAD5) (DEAD box protein 19B) | UniProt NCBI |
| S100A4 | Protein S100-A4 (Calvasculin) (Metastasin) (Placental calcium-binding protein) (Protein Mts1) (S100 calcium-binding protein A4) | UniProt NCBI |
| SULT2B1 | Sulfotransferase family cytosolic 2B member 1 (ST2B1) (Sulfotransferase 2B1) (EC 2.8.2.2) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2) | UniProt NCBI |
| C3 | Complement C3 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1) [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc); Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2] | UniProt NCBI |
| ALOX15 | Arachidonate 15-lipoxygenase (15-LOX) (15-LOX-1) (EC 1.13.11.33) (12/15-lipoxygenase) (Arachidonate 12-lipoxygenase, leukocyte-type) (12-LOX) (EC 1.13.11.31) (Arachidonate omega-6 lipoxygenase) | UniProt NCBI |
| IGHG1 | NCBI | |
| IGHG2 | NCBI | |
| IGKC | NCBI | |
| SERPINB7 | Serpin B7 (Megsin) (TP55) | UniProt NCBI |
| FCGBP | IgGFc-binding protein (Fcgamma-binding protein antigen) (FcgammaBP) | UniProt NCBI |
| CRABP2 | Cellular retinoic acid-binding protein 2 (Cellular retinoic acid-binding protein II) (CRABP-II) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0025080 | 0.000498144669412 | 0.25 | SERPINB7 SULT2B1 | Orthokeratotic hyperkeratosis |
| HP:0011124 | 0.00193157255722 | 0.375 | SERPINB7 SULT2B1 IL36RN | Abnormality of epidermal morphology |
| WP:WP716 | 0.00937362902178 | 0.25 | SULT2B1 CRABP2 | Vitamin A and Carotenoid Metabolism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDX19B | IL36RN | 0.288 | 0.489 | bioplex (DDX19B) bioplex_WMM |
| DDX19B | IGHG2 | 0.105 | 0.369 | bioplex (DDX19B) bioplex_WMM |
| DDX19B | IGHG1 | 0.087 | 0.353 | bioplex (DDX19B) bioplex_WMM |
| DDX19B | S100A4 | 0.08 | 0.351 | bioplex (DDX19B) bioplex_WMM |
| DDX19B | IGKC | 0.078 | 0.352 | bioplex (DDX19B) bioplex_WMM |
| SULT2B1 | DDX19B | 0.068 | 0.348 | bioplex (DDX19B) bioplex_WMM |
| IGHG1 | IGHG2 | 0.052 | 0.304 | bioplex_WMM WMM_only boldt_WMM |
| IGHG1 | IGKC | 0.048 | 0.295 | bioplex_WMM boldt boldt_WMM |
| DDX19B | FCGBP | 0.046 | 0.294 | bioplex (DDX19B) bioplex_WMM |
| DDX19B | ALOX15 | 0.044 | 0.28 | bioplex (DDX19B) bioplex_WMM |
| CRABP2 | DDX19B | 0.035 | 0.265 | hein_WMM bioplex (DDX19B) bioplex_WMM |
| DDX19B | C3 | 0.024 | 0.214 | bioplex (DDX19B) bioplex_WMM |
| SERPINB7 | DDX19B | 0.02 | 0.187 | bioplex (DDX19B) bioplex_WMM |
| C3 | IGHG2 | 0.016 | 0.161 | bioplex_WMM WMM_only boldt_WMM |
| IGHG2 | IGKC | 0.014 | 0.141 | bioplex_WMM WMM_only boldt_WMM |
| C3 | IGHG1 | 0.014 | 0.146 | bioplex_WMM boldt boldt_WMM |
| SULT2B1 | IL36RN | 0.012 | 0.146 | bioplex_WMM WMM_only boldt_WMM treiber_WMM |
| CRABP2 | IGKC | 0.011 | 0.136 | bioplex_WMM boldt boldt_WMM |
| CRABP2 | SULT2B1 | 0.011 | 0.145 | bioplex_WMM WMM_only boldt_WMM treiber_WMM |
| CRABP2 | C3 | 0.01 | 0.134 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| C3 | IGKC | 0.01 | 0.134 | bioplex_WMM boldt boldt_WMM |
| CRABP2 | IGHG1 | 0.01 | 0.129 | bioplex_WMM boldt boldt_WMM |
| SERPINB7 | IL36RN | 0.01 | 0.123 | bioplex_WMM WMM_only treiber_WMM |
| CRABP2 | IGHG2 | 0.01 | 0.115 | bioplex_WMM WMM_only boldt_WMM |
| CRABP2 | IL36RN | 0.01 | 0.1 | bioplex_WMM WMM_only boldt_WMM treiber_WMM |
| SULT2B1 | IGHG2 | 0.01 | 0.102 | bioplex_WMM WMM_only boldt_WMM |
| SULT2B1 | IGKC | 0.009 | 0.113 | bioplex_WMM WMM_only boldt_WMM |
| C3 | IL36RN | 0.009 | 0.104 | bioplex_WMM WMM_only boldt_WMM treiber_WMM |
| IGHG2 | IL36RN | 0.009 | 0.104 | bioplex_WMM WMM_only boldt_WMM |
| ALOX15 | FCGBP | 0.009 | 0.104 | bioplex_WMM WMM_only |
| SERPINB7 | SULT2B1 | 0.009 | 0.108 | bioplex_WMM WMM_only treiber_WMM |
| CRABP2 | SERPINB7 | 0.009 | 0.11 | bioplex_WMM WMM_only treiber_WMM |
| SULT2B1 | IGHG1 | 0.009 | 0.105 | bioplex_WMM WMM_only boldt_WMM |
| IL36RN | FCGBP | 0.009 | 0.108 | bioplex_WMM WMM_only |
| SULT2B1 | C3 | 0.009 | 0.103 | bioplex_WMM WMM_only boldt_WMM treiber_WMM |
| S100A4 | FCGBP | 0.009 | 0.095 | bioplex_WMM WMM_only |
| ALOX15 | IL36RN | 0.009 | 0.098 | bioplex_WMM WMM_only |
| SULT2B1 | FCGBP | 0.009 | 0.095 | bioplex_WMM WMM_only |
| CRABP2 | FCGBP | 0.009 | 0.095 | bioplex_WMM WMM_only |
| IGKC | IL36RN | 0.008 | 0.093 | bioplex_WMM WMM_only boldt_WMM |
| C3 | FCGBP | 0.008 | 0.094 | bioplex_WMM WMM_only |
| S100A4 | ALOX15 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| SULT2B1 | ALOX15 | 0.008 | 0.089 | bioplex_WMM WMM_only |
| CRABP2 | ALOX15 | 0.008 | 0.089 | bioplex_WMM WMM_only |
| SERPINB7 | FCGBP | 0.008 | 0.083 | bioplex_WMM WMM_only |
| C3 | ALOX15 | 0.008 | 0.086 | bioplex_WMM WMM_only |
| IGHG1 | IL36RN | 0.008 | 0.083 | bioplex_WMM WMM_only boldt_WMM |
| S100A4 | IL36RN | 0.008 | 0.085 | bioplex_WMM WMM_only |
| SULT2B1 | S100A4 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| CRABP2 | S100A4 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| SERPINB7 | ALOX15 | 0.008 | 0.068 | bioplex_WMM WMM_only |
| S100A4 | C3 | 0.008 | 0.066 | bioplex_WMM WMM_only |
| SERPINB7 | C3 | 0.008 | 0.06 | bioplex_WMM WMM_only treiber_WMM |
| SERPINB7 | S100A4 | 0.008 | 0.044 | bioplex_WMM WMM_only |
| IGHG2 | FCGBP | 0.008 | 0.044 | bioplex_WMM WMM_only |
| IGKC | FCGBP | 0.008 | 0.032 | bioplex_WMM WMM_only |
| SERPINB7 | IGKC | 0.008 | 0.025 | bioplex_WMM WMM_only |
| S100A4 | IGHG2 | 0.008 | 0.016 | bioplex_WMM WMM_only |
| IGHG2 | ALOX15 | 0.008 | 0.025 | bioplex_WMM WMM_only |
| IGHG1 | FCGBP | 0.008 | 0.012 | bioplex_WMM WMM_only |
| IGKC | ALOX15 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| S100A4 | IGKC | 0.007 | 0.004 | bioplex_WMM WMM_only |
| S100A4 | IGHG1 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| SERPINB7 | IGHG2 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| IGHG1 | ALOX15 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| SERPINB7 | IGHG1 | 0.007 | 0.001 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05061 has an average edge precision of 0.129 which is ranked 6834 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IL36RN | HuMAP2_05061 |
| DDX19B | HuMAP2_04216 HuMAP2_05061 |
| S100A4 | HuMAP2_04465 HuMAP2_05061 HuMAP2_06097 |
| SULT2B1 | HuMAP2_01769 HuMAP2_05061 |
| C3 | HuMAP2_04634 HuMAP2_05061 |
| ALOX15 | HuMAP2_05061 |
| IGHG1 | HuMAP2_05061 |
| IGHG2 | HuMAP2_05061 |
| IGKC | HuMAP2_05061 |
| SERPINB7 | HuMAP2_01199 HuMAP2_01998 HuMAP2_05061 |
| FCGBP | HuMAP2_05061 |
| CRABP2 | HuMAP2_00238 HuMAP2_05061 HuMAP2_05477 HuMAP2_06405 |