hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05062
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RHOC | Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9) | UniProt NCBI |
| DAAM1 | Disheveled-associated activator of morphogenesis 1 | UniProt NCBI |
| RHOD | Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1) | UniProt NCBI |
| DAAM2 | Disheveled-associated activator of morphogenesis 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5663220 | 0.000514250934249 | 0.75 | RHOC DAAM1 RHOD | RHO GTPases Activate Formins |
| REAC:R-HSA-195258 | 0.0064749029242 | 0.75 | RHOC DAAM1 RHOD | RHO GTPase Effectors |
| WP:WP428 | 0.00943843856088 | 0.5 | DAAM1 DAAM2 | Wnt Signaling |
| REAC:R-HSA-194315 | 0.0173883634433 | 0.75 | RHOC DAAM1 RHOD | Signaling by Rho GTPases |
| KEGG:04310 | 0.0212231461989 | 0.5 | DAAM1 DAAM2 | Wnt signaling pathway |
| CORUM:6722 | 0.0499140284799 | 0.25 | RHOD | FILIP1-RhoD complex |
| CORUM:6724 | 0.0499140284799 | 0.25 | RHOD | WHAMM-RhoD complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DAAM1 | RHOC | 0.085 | 0.349 | bioplex (RHOC) bioplex_WMM |
| DAAM1 | RHOD | 0.05 | 0.295 | bioplex (RHOD) bioplex_WMM |
| DAAM2 | RHOC | 0.05 | 0.295 | bioplex (RHOC) bioplex_WMM |
| DAAM1 | DAAM2 | 0.007 | 0.012 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05062 has an average edge precision of 0.238 which is ranked 5575 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RHOC | HuMAP2_03143 HuMAP2_03163 HuMAP2_04764 HuMAP2_05062 HuMAP2_05697 |
| DAAM1 | HuMAP2_01939 HuMAP2_03143 HuMAP2_05062 HuMAP2_05697 |
| RHOD | HuMAP2_01939 HuMAP2_03143 HuMAP2_05062 HuMAP2_05697 |
| DAAM2 | HuMAP2_03143 HuMAP2_03163 HuMAP2_05062 HuMAP2_05697 |