hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05065
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| AUH | Methylglutaconyl-CoA hydratase, mitochondrial (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase) (Itaconyl-CoA hydratase) (EC 4.2.1.56) | UniProt NCBI |
| ECHDC2 | Enoyl-CoA hydratase domain-containing protein 2, mitochondrial | UniProt NCBI |
| IVD | Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00280 | 0.00048313744261 | 0.666666666667 | AUH IVD | Valine, leucine and isoleucine degradation |
| REAC:R-HSA-70895 | 0.00114404160216 | 0.666666666667 | AUH IVD | Branched-chain amino acid catabolism |
| GO:0006635 | 0.00310781167151 | 1.0 | IVD AUH ECHDC2 | fatty acid beta-oxidation |
| GO:0019395 | 0.00804289309261 | 1.0 | IVD AUH ECHDC2 | fatty acid oxidation |
| GO:0034440 | 0.00865355719779 | 1.0 | IVD AUH ECHDC2 | lipid oxidation |
| GO:0009062 | 0.00962631496557 | 1.0 | IVD AUH ECHDC2 | fatty acid catabolic process |
| GO:0072329 | 0.0165384259681 | 1.0 | IVD AUH ECHDC2 | monocarboxylic acid catabolic process |
| HP:0001259 | 0.023156827915 | 0.666666666667 | AUH IVD | Coma |
| HP:0001942 | 0.0329433889933 | 0.666666666667 | AUH IVD | Metabolic acidosis |
| GO:0004300 | 0.0378589948753 | 0.666666666667 | AUH ECHDC2 | enoyl-CoA hydratase activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| AUH | ECHDC2 | 0.929 | 0.846 | bioplex (ECHDC2) bioplex_WMM |
| IVD | AUH | 0.115 | 0.384 | bioplex_WMM fraction |
Images
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Complex HuMAP2_05065 has an average edge precision of 0.615 which is ranked 1863 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| AUH | HuMAP2_03041 HuMAP2_04395 HuMAP2_05065 |
| ECHDC2 | HuMAP2_04395 HuMAP2_05065 |
| IVD | HuMAP2_01054 HuMAP2_01152 HuMAP2_03041 HuMAP2_05065 HuMAP2_05176 HuMAP2_05341 |