hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05071
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NAXE | NAD(P)H-hydrate epimerase (EC 5.1.99.6) (Apolipoprotein A-I-binding protein) (AI-BP) (NAD(P)HX epimerase) (YjeF N-terminal domain-containing protein 1) (YjeF_N1) | UniProt NCBI |
| IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) | UniProt NCBI |
| TBCA | Tubulin-specific chaperone A (TCP1-chaperonin cofactor A) (Tubulin-folding cofactor A) (CFA) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:404 | 0.0249904952816 | 0.333333333333 | IDH1 | Isocitrate dehydrogenase [NADP], cytoplasmic |
| REAC:R-HSA-2978092 | 0.0498572752401 | 0.333333333333 | IDH1 | Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate |
| REAC:R-HSA-389542 | 0.0498572752401 | 0.333333333333 | IDH1 | NADPH regeneration |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IDH1 | NAXE | 0.538 | 0.642 | bioplex_WMM fraction |
| IDH1 | TBCA | 0.5 | 0.621 | bioplex_WMM fraction |
| NAXE | TBCA | 0.0 | 0.01 | bioplex_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_05071 has an average edge precision of 0.424 which is ranked 3077 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NAXE | HuMAP2_00843 HuMAP2_02671 HuMAP2_05071 HuMAP2_05984 HuMAP2_06785 |
| IDH1 | HuMAP2_00182 HuMAP2_00843 HuMAP2_04319 HuMAP2_05071 HuMAP2_05968 HuMAP2_05984 |
| TBCA | HuMAP2_01747 HuMAP2_05071 |