hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05092
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EFNB2 | Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L) | UniProt NCBI |
| EFNB1 | Ephrin-B1 (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) [Cleaved into: Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF); Ephrin-B1 intracellular domain (Ephrin-B1 ICD)] | UniProt NCBI |
| SDC3 | Syndecan-3 (SYND3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4561 | 0.000287463336731 | 0.666666666667 | EFNB2 EFNB1 | Cell migration and invasion through p75NTR |
| REAC:R-HSA-3928664 | 0.000909962567223 | 0.666666666667 | EFNB2 EFNB1 | Ephrin signaling |
| REAC:R-HSA-3928662 | 0.00495307159189 | 0.666666666667 | EFNB2 EFNB1 | EPHB-mediated forward signaling |
| KEGG:04360 | 0.00601503157228 | 0.666666666667 | EFNB2 EFNB1 | Axon guidance |
| REAC:R-HSA-3928665 | 0.00691608633843 | 0.666666666667 | EFNB2 EFNB1 | EPH-ephrin mediated repulsion of cells |
| MIRNA:hsa-miR-3689f | 0.00953008387352 | 0.666666666667 | EFNB2 SDC3 | hsa-miR-3689f |
| MIRNA:hsa-miR-3689a-5p | 0.00997289627319 | 0.666666666667 | EFNB2 SDC3 | hsa-miR-3689a-5p |
| MIRNA:hsa-miR-3689b-5p | 0.00997289627319 | 0.666666666667 | EFNB2 SDC3 | hsa-miR-3689b-5p |
| MIRNA:hsa-miR-3689e | 0.00997289627319 | 0.666666666667 | EFNB2 SDC3 | hsa-miR-3689e |
| REAC:R-HSA-2682334 | 0.0243796532655 | 0.666666666667 | EFNB2 EFNB1 | EPH-Ephrin signaling |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EFNB2 | EFNB1 | 1.0 | 0.949 | bioplex (EFNB2) bioplex_WMM gupta_WMM |
| EFNB2 | SDC3 | 0.903 | 0.827 | bioplex (EFNB2) bioplex_WMM |
| EFNB1 | SDC3 | 0.008 | 0.027 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05092 has an average edge precision of 0.601 which is ranked 1942 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| EFNB2 | HuMAP2_00251 HuMAP2_02549 HuMAP2_03654 HuMAP2_05092 |
| EFNB1 | HuMAP2_00251 HuMAP2_02549 HuMAP2_03654 HuMAP2_05092 |
| SDC3 | HuMAP2_00251 HuMAP2_02549 HuMAP2_03654 HuMAP2_05092 |