hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05095
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| VPS29 | Vacuolar protein sorting-associated protein 29 (hVPS29) (PEP11 homolog) (Vesicle protein sorting 29) | UniProt NCBI |
| VPS35 | Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35) | UniProt NCBI |
| VPS26A | Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A) (hVPS26) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:656 | 2.25356268047e-10 | 1.0 | VPS35 VPS26A VPS29 | VPS35-VPS29-VPS26A complex |
| CORUM:657 | 2.25356268047e-09 | 1.0 | VPS35 VPS26A VPS29 | Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) |
| CORUM:1059 | 2.25356268047e-09 | 1.0 | VPS35 VPS26A VPS29 | Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) |
| GO:0030906 | 3.63274304092e-07 | 1.0 | VPS35 VPS26A VPS29 | retromer, cargo-selective complex |
| REAC:R-HSA-3238698 | 7.96236129391e-07 | 1.0 | VPS35 VPS26A VPS29 | WNT ligand biogenesis and trafficking |
| CORUM:1060 | 3.35555483123e-05 | 0.666666666667 | VPS35 VPS29 | Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26B) |
| KEGG:04144 | 6.09806140287e-05 | 1.0 | VPS35 VPS26A VPS29 | Endocytosis |
| GO:0030904 | 7.41079580349e-05 | 1.0 | VPS35 VPS26A VPS29 | retromer complex |
| GO:1990126 | 0.000208882724853 | 1.0 | VPS35 VPS26A VPS29 | retrograde transport, endosome to plasma membrane |
| REAC:R-HSA-195721 | 0.00221076692273 | 1.0 | VPS35 VPS26A VPS29 | Signaling by WNT |
| GO:0098876 | 0.00613252434596 | 1.0 | VPS35 VPS26A VPS29 | vesicle-mediated transport to the plasma membrane |
| GO:0042147 | 0.00774864090629 | 1.0 | VPS35 VPS26A VPS29 | retrograde transport, endosome to Golgi |
| GO:0097422 | 0.0135228859698 | 0.666666666667 | VPS35 VPS26A | tubular endosome |
| GO:0016482 | 0.043337807111 | 1.0 | VPS35 VPS26A VPS29 | cytosolic transport |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VPS35 | VPS26A | 1.0 | 0.949 | hein_WMM bioplex (VPS26A) bioplex_WMM Guru hein (VPS26A) gupta_WMM fraction |
| VPS26A | VPS29 | 1.0 | 0.949 | hein_WMM bioplex (VPS26A,VPS29) bioplex_WMM Guru hein (VPS26A) gupta_WMM fraction |
| VPS35 | VPS29 | 0.999 | 0.949 | hein_WMM bioplex (VPS29) bioplex_WMM Guru gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_05095 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes