hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05098
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GPRC5A | Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1) | UniProt NCBI |
| FLOT2 | Flotillin-2 (Epidermal surface antigen) (ESA) (Membrane component chromosome 17 surface marker 1) | UniProt NCBI |
| BASP1 | Brain acid soluble protein 1 (22 kDa neuronal tissue-enriched acidic protein) (Neuronal axonal membrane protein NAP-22) | UniProt NCBI |
| DSG2 | Desmoglein-2 (Cadherin family member 5) (HDGC) | UniProt NCBI |
| FLOT1 | Flotillin-1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8849932 | 0.00255837003151 | 0.4 | FLOT1 FLOT2 | Synaptic adhesion-like molecules |
| MIRNA:hsa-miR-3150b-3p | 0.00778945845492 | 0.6 | BASP1 FLOT2 GPRC5A | hsa-miR-3150b-3p |
| MIRNA:hsa-miR-4784 | 0.00790320546329 | 0.6 | BASP1 FLOT2 GPRC5A | hsa-miR-4784 |
| GO:0044291 | 0.0103850554114 | 0.6 | FLOT1 DSG2 FLOT2 | cell-cell contact zone |
| MIRNA:hsa-miR-4445-5p | 0.0246863700739 | 0.4 | BASP1 FLOT2 | hsa-miR-4445-5p |
| WP:WP3915 | 0.0250517914711 | 0.4 | FLOT1 FLOT2 | Angiopoietin Like Protein 8 Regulatory Pathway |
| KEGG:04910 | 0.0327287628992 | 0.4 | FLOT1 FLOT2 | Insulin signaling pathway |
| WP:WP481 | 0.0385448371419 | 0.4 | FLOT1 FLOT2 | Insulin Signaling |
| REAC:R-HSA-6794362 | 0.0432704002666 | 0.4 | FLOT1 FLOT2 | Protein-protein interactions at synapses |
| GO:1903044 | 0.0450641792523 | 0.4 | FLOT1 FLOT2 | protein localization to membrane raft |
| MIRNA:hsa-miR-3189-3p | 0.0482780268961 | 0.4 | BASP1 GPRC5A | hsa-miR-3189-3p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FLOT2 | FLOT1 | 0.99 | 0.909 | hein_WMM bioplex_WMM youn_WMM hein (FLOT1,FLOT2) |
| FLOT2 | BASP1 | 0.163 | 0.42 | hein_WMM bioplex (FLOT2) bioplex_WMM hein (FLOT2) gupta_WMM |
| DSG2 | FLOT2 | 0.078 | 0.353 | hein_WMM bioplex (FLOT2) bioplex_WMM youn_WMM hein (FLOT2) gupta_WMM |
| FLOT2 | GPRC5A | 0.049 | 0.293 | hein_WMM hein (FLOT2) gupta_WMM |
| DSG2 | FLOT1 | 0.023 | 0.209 | hein_WMM bioplex_WMM youn_WMM hein (FLOT1) |
| FLOT1 | GPRC5A | 0.014 | 0.137 | hein_WMM hein (FLOT1) |
| DSG2 | BASP1 | 0.009 | 0.108 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| BASP1 | FLOT1 | 0.006 | 0.008 | hein_WMM bioplex_WMM hein (FLOT1) |
| DSG2 | GPRC5A | 0.005 | 0.013 | hein_WMM gupta_WMM WMM_only |
| BASP1 | GPRC5A | 0.004 | 0.012 | hein_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_05098 has an average edge precision of 0.246 which is ranked 5432 out of all 6965 complexes.
Related Complexes