hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05100
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ARHGEF35 | Rho guanine nucleotide exchange factor 35 (Rho guanine nucleotide exchange factor 5-like protein) | UniProt NCBI |
| ARHGEF5 | Rho guanine nucleotide exchange factor 5 (Ephexin-3) (Guanine nucleotide regulatory protein TIM) (Oncogene TIM) (Transforming immortalized mammary oncogene) (p60 TIM) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-193648 | 0.00230942253115 | 1.0 | ARHGEF35 ARHGEF5 | NRAGE signals death through JNK |
| REAC:R-HSA-204998 | 0.00381775364729 | 1.0 | ARHGEF35 ARHGEF5 | Cell death signalling via NRAGE, NRIF and NADE |
| REAC:R-HSA-416482 | 0.00440432685912 | 1.0 | ARHGEF35 ARHGEF5 | G alpha (12/13) signalling events |
| REAC:R-HSA-193704 | 0.00612550025498 | 1.0 | ARHGEF35 ARHGEF5 | p75 NTR receptor-mediated signalling |
| REAC:R-HSA-73887 | 0.0131978972662 | 1.0 | ARHGEF35 ARHGEF5 | Death Receptor Signalling |
| REAC:R-HSA-194840 | 0.0142704882821 | 1.0 | ARHGEF35 ARHGEF5 | Rho GTPase cycle |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ARHGEF35 | ARHGEF5 | 1.0 | 0.949 | bioplex (ARHGEF35) bioplex_WMM youn_WMM |
Images
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Complex HuMAP2_05100 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ARHGEF35 | HuMAP2_00836 HuMAP2_05100 |
| ARHGEF5 | HuMAP2_00836 HuMAP2_05100 |