hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05119
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MSL2 | E3 ubiquitin-protein ligase MSL2 (EC 2.3.2.-) (E3 ubiquitin-protein transferase MSL2) (Male-specific lethal 2-like 1) (MSL2-like 1) (Male-specific lethal-2 homolog) (MSL-2) (Male-specific lethal-2 homolog 1) (RING finger protein 184) | UniProt NCBI |
| KAT8 | Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (hMOF) | UniProt NCBI |
| MSL3 | Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1) | UniProt NCBI |
| MSL1 | Male-specific lethal 1 homolog (MSL-1) (Male-specific lethal 1-like 1) (MSL1-like 1) (Male-specific lethal-1 homolog 1) | UniProt NCBI |
| MSL3P1 | NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7220 | 4.53449095762e-14 | 1.0 | MSL1 KAT8 MSL3 MSL2 | MSL complex |
| GO:0072487 | 2.4395561352e-11 | 1.0 | MSL1 KAT8 MSL3 MSL2 | MSL complex |
| CORUM:610 | 2.70078815927e-09 | 0.75 | KAT8 MSL3 MSL2 | MSL complex |
| GO:0043984 | 5.80614360177e-08 | 1.0 | MSL1 KAT8 MSL3 MSL2 | histone H4-K16 acetylation |
| REAC:R-HSA-3214847 | 1.47230432248e-06 | 1.0 | MSL1 KAT8 MSL3 MSL2 | HATs acetylate histones |
| GO:1902562 | 2.47053849812e-06 | 1.0 | MSL1 KAT8 MSL3 MSL2 | H4 histone acetyltransferase complex |
| GO:0043967 | 7.1436302529e-06 | 1.0 | MSL1 KAT8 MSL3 MSL2 | histone H4 acetylation |
| REAC:R-HSA-4839726 | 1.93476074015e-05 | 1.0 | MSL1 KAT8 MSL3 MSL2 | Chromatin organization |
| REAC:R-HSA-3247509 | 1.93476074015e-05 | 1.0 | MSL1 KAT8 MSL3 MSL2 | Chromatin modifying enzymes |
| GO:0000123 | 3.47984386015e-05 | 1.0 | MSL1 KAT8 MSL3 MSL2 | histone acetyltransferase complex |
| GO:1902493 | 5.68877655611e-05 | 1.0 | MSL1 KAT8 MSL3 MSL2 | acetyltransferase complex |
| GO:0031248 | 5.68877655611e-05 | 1.0 | MSL1 KAT8 MSL3 MSL2 | protein acetyltransferase complex |
| GO:0016573 | 0.000125895977869 | 1.0 | MSL1 KAT8 MSL3 MSL2 | histone acetylation |
| GO:0018393 | 0.000135718631087 | 1.0 | MSL1 KAT8 MSL3 MSL2 | internal peptidyl-lysine acetylation |
| GO:0006475 | 0.000162788555852 | 1.0 | MSL1 KAT8 MSL3 MSL2 | internal protein amino acid acetylation |
| GO:0018394 | 0.000168654810117 | 1.0 | MSL1 KAT8 MSL3 MSL2 | peptidyl-lysine acetylation |
| GO:0006473 | 0.000455512457831 | 1.0 | MSL1 KAT8 MSL3 MSL2 | protein acetylation |
| GO:0043543 | 0.00107888479641 | 1.0 | MSL1 KAT8 MSL3 MSL2 | protein acylation |
| GO:0018205 | 0.00665909549353 | 1.0 | MSL1 KAT8 MSL3 MSL2 | peptidyl-lysine modification |
| GO:0016570 | 0.0111323368581 | 1.0 | MSL1 KAT8 MSL3 MSL2 | histone modification |
| GO:0016569 | 0.0133451908966 | 1.0 | MSL1 KAT8 MSL3 MSL2 | covalent chromatin modification |
| CORUM:724 | 0.0499140284799 | 0.25 | KAT8 | MAF2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MSL1 | KAT8 | 1.0 | 0.949 | hein_WMM bioplex (MSL1) bioplex_WMM hein (KAT8) |
| MSL1 | MSL3 | 0.985 | 0.899 | hein_WMM bioplex (MSL1) bioplex_WMM |
| MSL2 | KAT8 | 0.703 | 0.724 | hein_WMM bioplex (MSL2) bioplex_WMM hein (KAT8) |
| MSL1 | MSL3P1 | 0.638 | 0.685 | bioplex (MSL1) bioplex_WMM |
| MSL2 | MSL1 | 0.306 | 0.501 | hein_WMM bioplex (MSL2) bioplex_WMM |
| KAT8 | MSL3 | 0.146 | 0.409 | hein_WMM bioplex_WMM hein (KAT8) |
| MSL2 | MSL3 | 0.095 | 0.359 | hein_WMM bioplex (MSL2) bioplex_WMM |
| KAT8 | MSL3P1 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| MSL3 | MSL3P1 | 0.009 | 0.096 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05119 has an average edge precision of 0.526 which is ranked 2369 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MSL2 | HuMAP2_00337 HuMAP2_03206 HuMAP2_03592 HuMAP2_05119 |
| KAT8 | HuMAP2_00337 HuMAP2_00495 HuMAP2_03592 HuMAP2_05119 |
| MSL3 | HuMAP2_00337 HuMAP2_03153 HuMAP2_03206 HuMAP2_05119 HuMAP2_05861 |
| MSL1 | HuMAP2_00337 HuMAP2_03153 HuMAP2_05119 HuMAP2_05861 |
| MSL3P1 | HuMAP2_00337 HuMAP2_03153 HuMAP2_05119 |