hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05135
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MEIOC | Meiosis-specific coiled-coil domain-containing protein MEIOC (Meiosis-specific with coiled-coil domain protein) | UniProt NCBI |
| ZNF223 | Zinc finger protein 223 | UniProt NCBI |
| ZNF550 | Zinc finger protein 550 | UniProt NCBI |
| YTHDC2 | 3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2) (hYTHDC2) | UniProt NCBI |
| ZNF714 | Zinc finger protein 714 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0051728 | 0.00270494046827 | 0.5 | YTHDC2 MEIOC | cell cycle switching, mitotic to meiotic cell cycle |
| GO:0051729 | 0.00270494046827 | 0.5 | YTHDC2 MEIOC | germline cell cycle switching, mitotic to meiotic cell cycle |
| GO:0060184 | 0.00270494046827 | 0.5 | YTHDC2 MEIOC | cell cycle switching |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZNF550 | MEIOC | 0.355 | 0.54 | bioplex (ZNF550) bioplex_WMM |
| ZNF550 | YTHDC2 | 0.148 | 0.409 | bioplex (ZNF550) bioplex_WMM |
| ZNF223 | ZNF714 | 0.075 | 0.356 | bioplex (ZNF223) bioplex_WMM |
| ZNF714 | ZNF550 | 0.064 | 0.348 | bioplex (ZNF550) bioplex_WMM |
| ZNF714 | MEIOC | 0.008 | 0.067 | bioplex_WMM WMM_only |
| MEIOC | YTHDC2 | 0.008 | 0.039 | bioplex_WMM youn_WMM WMM_only |
| ZNF714 | YTHDC2 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| ZNF223 | YTHDC2 | 0.004 | 0.012 | bioplex (ZNF223) bioplex_WMM |
Images
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Complex HuMAP2_05135 has an average edge precision of 0.222 which is ranked 5823 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MEIOC | HuMAP2_01124 HuMAP2_01453 HuMAP2_02655 HuMAP2_05135 |
| ZNF223 | HuMAP2_00513 HuMAP2_05135 |
| ZNF550 | HuMAP2_01124 HuMAP2_01453 HuMAP2_02655 HuMAP2_02973 HuMAP2_05135 |
| YTHDC2 | HuMAP2_01124 HuMAP2_02973 HuMAP2_05135 HuMAP2_06905 |
| ZNF714 | HuMAP2_00513 HuMAP2_05135 |