hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_05136

Confidence: Very High

Genename	Protein Name	Links
ELL	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein)	UniProt NCBI
ICE1	Little elongation complex subunit 1 (Interactor of little elongator complex ELL subunit 1)	UniProt NCBI
EAF1	ELL-associated factor 1	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:6084	0.000184505937338	0.666666666667	ELL EAF1	AFF4 super elongation complex (SEC)
GO:0008023	0.00178004409005	1.0	ELL ICE1 EAF1	transcription elongation factor complex
GO:0035363	0.00811409485621	0.666666666667	ELL ICE1	histone locus body
REAC:R-HSA-112382	0.011426592715	0.666666666667	ELL EAF1	Formation of RNA Pol II elongation complex
REAC:R-HSA-75955	0.011426592715	0.666666666667	ELL EAF1	RNA Polymerase II Transcription Elongation
REAC:R-HSA-6807505	0.0180259784934	0.666666666667	ELL ICE1	RNA polymerase II transcribes snRNA genes
GO:0042796	0.020283420769	0.666666666667	ELL ICE1	snRNA transcription by RNA polymerase III
REAC:R-HSA-674695	0.022155781492	0.666666666667	ELL EAF1	RNA Polymerase II Pre-transcription Events
GO:0045945	0.0486736709081	0.666666666667	ELL ICE1	positive regulation of transcription by RNA polymerase III

Protein 1	Protein 2	Score	Precision	Evidence
ELL	EAF1	0.999	0.948	bioplex (EAF1) bioplex_WMM fraction
ICE1	EAF1	0.966	0.876	bioplex (EAF1) bioplex_WMM
ELL	ICE1	0.012	0.147	hein_WMM bioplex_WMM youn_WMM WMM_only

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ComplexPrecisionDistribution

Complex HuMAP2_05136 has an average edge precision of 0.657 which is ranked 1609 out of all 6965 complexes.

Related Complexes

Genename	Complexes
ELL	HuMAP2_01292 HuMAP2_05123 HuMAP2_05136
ICE1	HuMAP2_01292 HuMAP2_04584 HuMAP2_05123 HuMAP2_05136
EAF1	HuMAP2_01292 HuMAP2_04584 HuMAP2_05123 HuMAP2_05136