hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05151
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| VIPAS39 | Spermatogenesis-defective protein 39 homolog (hSPE-39) (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction) | UniProt NCBI |
| MATN1 | Cartilage matrix protein (Matrilin-1) | UniProt NCBI |
| VPS33B | Vacuolar protein sorting-associated protein 33B (hVPS33B) | UniProt NCBI |
| CILP2 | Cartilage intermediate layer protein 2 (CILP-2) [Cleaved into: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2] | UniProt NCBI |
| MATN4 | Matrilin-4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6390 | 6.70868171695e-06 | 0.4 | VPS33B VIPAS39 | Endosomal targeting complex (VIPAS39-VPS33B) |
| HP:0009806 | 0.000278784943944 | 0.4 | VPS33B VIPAS39 | Nephrogenic diabetes insipidus |
| HP:0200084 | 0.000278784943944 | 0.4 | VPS33B VIPAS39 | Giant cell hepatitis |
| HP:0001884 | 0.00097535418756 | 0.4 | VPS33B VIPAS39 | Talipes calcaneovalgus |
| HP:0002611 | 0.0025531267598 | 0.4 | VPS33B VIPAS39 | Cholestatic liver disease |
| HP:0001667 | 0.00422256197273 | 0.4 | VPS33B VIPAS39 | Right ventricular hypertrophy |
| HP:0002908 | 0.00422256197273 | 0.4 | VPS33B VIPAS39 | Conjugated hyperbilirubinemia |
| HP:0001707 | 0.00880923289202 | 0.4 | VPS33B VIPAS39 | Abnormal right ventricle morphology |
| HP:0001947 | 0.0162585949147 | 0.4 | VPS33B VIPAS39 | Renal tubular acidosis |
| HP:0000873 | 0.0259615168254 | 0.4 | VPS33B VIPAS39 | Diabetes insipidus |
| REAC:R-HSA-3000178 | 0.0287045163353 | 0.4 | MATN1 MATN4 | ECM proteoglycans |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MATN1 | MATN4 | 0.839 | 0.784 | bioplex (MATN4) bioplex_WMM |
| MATN4 | VIPAS39 | 0.111 | 0.381 | bioplex (MATN4) bioplex_WMM |
| VPS33B | MATN4 | 0.11 | 0.379 | bioplex (MATN4) bioplex_WMM |
| MATN4 | CILP2 | 0.023 | 0.21 | bioplex (MATN4) bioplex_WMM |
| VPS33B | VIPAS39 | 0.015 | 0.139 | bioplex_WMM youn_WMM WMM_only |
| MATN1 | CILP2 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| MATN1 | VIPAS39 | 0.008 | 0.082 | bioplex_WMM WMM_only |
| VPS33B | MATN1 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| VIPAS39 | CILP2 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| VPS33B | CILP2 | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05151 has an average edge precision of 0.215 which is ranked 5940 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| VIPAS39 | HuMAP2_03509 HuMAP2_04231 HuMAP2_05151 HuMAP2_05579 |
| MATN1 | HuMAP2_01894 HuMAP2_05151 HuMAP2_05579 |
| VPS33B | HuMAP2_01416 HuMAP2_03509 HuMAP2_04231 HuMAP2_05151 |
| CILP2 | HuMAP2_03717 HuMAP2_05151 HuMAP2_05505 HuMAP2_05579 |
| MATN4 | HuMAP2_01894 HuMAP2_04231 HuMAP2_05151 HuMAP2_05579 |