hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05181
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DOHH | Deoxyhypusine hydroxylase (hDOHH) (EC 1.14.99.29) (Deoxyhypusine dioxygenase) (Deoxyhypusine monooxygenase) (HEAT-like repeat-containing protein 1) | UniProt NCBI |
| EIF5A2 | Eukaryotic translation initiation factor 5A-2 (eIF-5A-2) (eIF-5A2) (Eukaryotic initiation factor 5A isoform 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-204626 | 1.00555407742e-05 | 1.0 | DOHH EIF5A2 | Hypusine synthesis from eIF5A-lysine |
| REAC:R-HSA-163841 | 0.000997174460113 | 1.0 | DOHH EIF5A2 | Gamma carboxylation, hypusine formation and arylsulfatase activation |
| HPA:053050_23 | 0.0374367783025 | 0.5 | EIF5A2 | testis; peritubular cells[Approved,High] |
| HPA:053050_22 | 0.0499140284799 | 0.5 | EIF5A2 | testis; peritubular cells[Approved,Medium] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EIF5A2 | DOHH | 1.0 | 0.949 | bioplex (DOHH) bioplex_WMM fraction |
Images
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Complex HuMAP2_05181 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DOHH | HuMAP2_01097 HuMAP2_02542 HuMAP2_04788 HuMAP2_04817 HuMAP2_05181 |
| EIF5A2 | HuMAP2_00526 HuMAP2_02855 HuMAP2_04817 HuMAP2_05181 |