hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05182
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| USP20 | Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.4.19.12) (Deubiquitinating enzyme 20) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (VHL-interacting deubiquitinating enzyme 2) (hVDU2) | UniProt NCBI |
| APBA1 | Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1) | UniProt NCBI |
| APBA2 | Amyloid-beta A4 precursor protein-binding family A member 2 (Adapter protein X11beta) (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) | UniProt NCBI |
| IQSEC2 | IQ motif and SEC7 domain-containing protein 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6794361 | 0.0137933430055 | 0.5 | APBA1 APBA2 | Neurexins and neuroligins |
| REAC:R-HSA-6794362 | 0.0323499619092 | 0.5 | APBA1 APBA2 | Protein-protein interactions at synapses |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| APBA1 | APBA2 | 0.998 | 0.939 | bioplex (APBA2) bioplex_WMM |
| USP20 | APBA2 | 0.143 | 0.405 | bioplex (APBA2) bioplex_WMM |
| APBA2 | IQSEC2 | 0.097 | 0.359 | bioplex (APBA2) bioplex_WMM |
| APBA1 | IQSEC2 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| APBA1 | USP20 | 0.008 | 0.026 | bioplex_WMM WMM_only |
| USP20 | IQSEC2 | 0.008 | 0.026 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05182 has an average edge precision of 0.307 which is ranked 4485 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| USP20 | HuMAP2_02083 HuMAP2_03905 HuMAP2_05182 |
| APBA1 | HuMAP2_02083 HuMAP2_03001 HuMAP2_05182 HuMAP2_05226 |
| APBA2 | HuMAP2_02083 HuMAP2_05182 HuMAP2_05226 |
| IQSEC2 | HuMAP2_02083 HuMAP2_05182 |