hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05186
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EHD4 | EH domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11) (PAST homolog 4) | UniProt NCBI |
| VPS45 | Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45) | UniProt NCBI |
| EHD3 | EH domain-containing protein 3 (PAST homolog 3) | UniProt NCBI |
| RBSN | Rabenosyn-5 (110 kDa protein) (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20) | UniProt NCBI |
| STX16 | Syntaxin-16 (Syn16) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04144 | 1.32635921507e-05 | 0.8 | EHD3 VPS45 RBSN EHD4 | Endocytosis |
| REAC:R-HSA-983231 | 0.00175946619988 | 0.6 | VPS45 RBSN EHD3 | Factors involved in megakaryocyte development and platelet production |
| GO:0016197 | 0.00780704088192 | 0.8 | EHD4 EHD3 RBSN STX16 | endosomal transport |
| REAC:R-HSA-6811438 | 0.0126969553517 | 0.4 | VPS45 STX16 | Intra-Golgi traffic |
| GO:0010008 | 0.02802299347 | 0.8 | EHD3 VPS45 RBSN EHD4 | endosome membrane |
| GO:0044440 | 0.0476611208993 | 0.8 | EHD3 VPS45 RBSN EHD4 | endosomal part |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VPS45 | RBSN | 0.987 | 0.901 | bioplex (RBSN,VPS45) bioplex_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM |
| VPS45 | STX16 | 0.703 | 0.723 | bioplex (VPS45) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
| RBSN | EHD3 | 0.191 | 0.444 | bioplex (RBSN) bioplex_WMM |
| RBSN | EHD4 | 0.083 | 0.349 | bioplex (RBSN) bioplex_WMM |
| STX16 | RBSN | 0.008 | 0.066 | bioplex_WMM youn_WMM WMM_only |
| VPS45 | EHD3 | 0.008 | 0.066 | bioplex_WMM WMM_only |
| EHD3 | EHD4 | 0.008 | 0.011 | bioplex_WMM WMM_only boldt_WMM |
| STX16 | EHD4 | 0.007 | 0.006 | gupta_WMM WMM_only |
| VPS45 | EHD4 | 0.006 | 0.004 | bioplex_WMM Guru youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_05186 has an average edge precision of 0.286 which is ranked 4804 out of all 6965 complexes.
Related Complexes