hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05189
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FBXL5 | F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein) | UniProt NCBI |
| MAPK6 | Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK) | UniProt NCBI |
| MAPKAPK5 | MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK) | UniProt NCBI |
| ZNF28 | Zinc finger protein 28 (Zinc finger protein KOX24) | UniProt NCBI |
| ZNF468 | Zinc finger protein 468 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7548 | 2.0123342217e-05 | 0.4 | MAPK6 MAPKAPK5 | MAPK6-MAPKAPK5-SEPT7 complex |
| REAC:R-HSA-5687128 | 0.0499209306556 | 0.4 | MAPK6 MAPKAPK5 | MAPK6/MAPK4 signaling |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MAPKAPK5 | MAPK6 | 0.981 | 0.896 | bioplex (MAPK6) bioplex_WMM |
| ZNF468 | MAPK6 | 0.66 | 0.696 | bioplex (MAPK6) bioplex_WMM |
| MAPK6 | FBXL5 | 0.403 | 0.562 | bioplex (FBXL5) bioplex_WMM |
| MAPK6 | ZNF28 | 0.098 | 0.357 | bioplex (MAPK6) bioplex_WMM |
| ZNF468 | MAPKAPK5 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| MAPKAPK5 | ZNF28 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| ZNF468 | ZNF28 | 0.008 | 0.091 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05189 has an average edge precision of 0.398 which is ranked 3348 out of all 6965 complexes.
Related Complexes