hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05191
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TRAF3IP2 | Adapter protein CIKS (Connection to IKK and SAPK/JNK) (Nuclear factor NF-kappa-B activator 1) (ACT1) (TRAF3-interacting protein 2) | UniProt NCBI |
| TRIM24 | Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24) | UniProt NCBI |
| TRIM33 | E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33) | UniProt NCBI |
| QPRT | Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (QPRTase) | UniProt NCBI |
| HIPK2 | Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04218 | 0.0439700127241 | 0.4 | TRAF3IP2 HIPK2 | Cellular senescence |
| WP:WP3938 | 0.0497141369515 | 0.2 | HIPK2 | miR-222 in Exercise-Induced Cardiac Growth |
| CORUM:2704 | 0.0499494897235 | 0.2 | TRIM33 | Ectodermin-SMAD4 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| QPRT | TRIM33 | 0.478 | 0.61 | bioplex (QPRT) bioplex_WMM |
| TRIM24 | TRIM33 | 0.35 | 0.536 | hein_WMM bioplex_WMM youn_WMM hein (TRIM33) gupta_WMM |
| TRAF3IP2 | QPRT | 0.104 | 0.369 | bioplex (QPRT) bioplex_WMM |
| QPRT | HIPK2 | 0.087 | 0.352 | bioplex (QPRT) bioplex_WMM |
| TRAF3IP2 | HIPK2 | 0.009 | 0.102 | bioplex_WMM WMM_only |
| TRIM24 | TRAF3IP2 | 0.008 | 0.08 | bioplex_WMM WMM_only |
| TRAF3IP2 | TRIM33 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| TRIM24 | HIPK2 | 0.008 | 0.032 | bioplex_WMM WMM_only |
| HIPK2 | TRIM33 | 0.008 | 0.027 | bioplex_WMM WMM_only |
| TRIM24 | QPRT | 0.0 | 0.002 | bioplex (QPRT) bioplex_WMM |
Images
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Complex HuMAP2_05191 has an average edge precision of 0.217 which is ranked 5908 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TRAF3IP2 | HuMAP2_04358 HuMAP2_05191 |
| TRIM24 | HuMAP2_02504 HuMAP2_03221 HuMAP2_05191 |
| TRIM33 | HuMAP2_05191 |
| QPRT | HuMAP2_04358 HuMAP2_05191 |
| HIPK2 | HuMAP2_04358 HuMAP2_05191 |