hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05195
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NDUFB4 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (Complex I-B15) (CI-B15) (NADH-ubiquinone oxidoreductase B15 subunit) | UniProt NCBI |
| NDUFA10 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit) | UniProt NCBI |
| ACAD10 | Acyl-CoA dehydrogenase family member 10 (ACAD-10) (EC 1.3.99.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4324 | 0.00131875812108 | 0.666666666667 | NDUFB4 NDUFA10 | Mitochondrial complex I assembly model OXPHOS system |
| WP:WP623 | 0.00142103052979 | 0.666666666667 | NDUFB4 NDUFA10 | Oxidative phosphorylation |
| CORUM:178 | 0.00261323128428 | 0.666666666667 | NDUFB4 NDUFA10 | Respiratory chain complex I (holoenzyme), mitochondrial |
| KEGG:00190 | 0.00307537091529 | 0.666666666667 | NDUFB4 NDUFA10 | Oxidative phosphorylation |
| KEGG:05012 | 0.00350714576187 | 0.666666666667 | NDUFB4 NDUFA10 | Parkinson disease |
| KEGG:04723 | 0.00384947200959 | 0.666666666667 | NDUFB4 NDUFA10 | Retrograde endocannabinoid signaling |
| KEGG:04932 | 0.00390806659107 | 0.666666666667 | NDUFB4 NDUFA10 | Non-alcoholic fatty liver disease (NAFLD) |
| WP:WP111 | 0.00408673569856 | 0.666666666667 | NDUFB4 NDUFA10 | Electron Transport Chain (OXPHOS system in mitochondria) |
| KEGG:05010 | 0.00524007678336 | 0.666666666667 | NDUFB4 NDUFA10 | Alzheimer disease |
| KEGG:05016 | 0.00684298122566 | 0.666666666667 | NDUFB4 NDUFA10 | Huntington disease |
| REAC:R-HSA-6799198 | 0.008858224502 | 0.666666666667 | NDUFB4 NDUFA10 | Complex I biogenesis |
| WP:WP4396 | 0.00888189132931 | 0.666666666667 | NDUFB4 NDUFA10 | Nonalcoholic fatty liver disease |
| KEGG:04714 | 0.00964399884594 | 0.666666666667 | NDUFB4 NDUFA10 | Thermogenesis |
| REAC:R-HSA-611105 | 0.0291450496188 | 0.666666666667 | NDUFB4 NDUFA10 | Respiratory electron transport |
| REAC:R-HSA-163200 | 0.0444303896492 | 0.666666666667 | NDUFB4 NDUFA10 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NDUFA10 | NDUFB4 | 0.065 | 0.347 | hein_WMM bioplex_WMM gupta_WMM fraction |
| NDUFA10 | ACAD10 | 0.042 | 0.27 | bioplex (NDUFA10) bioplex_WMM |
| NDUFB4 | ACAD10 | 0.006 | 0.007 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05195 has an average edge precision of 0.208 which is ranked 6059 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NDUFB4 | HuMAP2_00221 HuMAP2_01573 HuMAP2_05195 |
| NDUFA10 | HuMAP2_00221 HuMAP2_01573 HuMAP2_02247 HuMAP2_02701 HuMAP2_03335 HuMAP2_05195 HuMAP2_06516 |
| ACAD10 | HuMAP2_00221 HuMAP2_01316 HuMAP2_02247 HuMAP2_05195 HuMAP2_05844 |