hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05200
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DPH3 | DPH3 homolog (CSL-type zinc finger-containing protein 2) (DelGEF-interacting protein 1) (DelGIP1) | UniProt NCBI |
| SERGEF | Secretion-regulating guanine nucleotide exchange factor (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF) (Guanine nucleotide exchange factor-related protein) | UniProt NCBI |
| DPH2 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (EC 2.5.1.108) (Diphthamide biosynthesis protein 2) (Diphtheria toxin resistance protein 2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5358493 | 0.000187420766709 | 0.666666666667 | DPH3 DPH2 | Synthesis of diphthamide-EEF2 |
| REAC:R-HSA-163841 | 0.00397787610966 | 0.666666666667 | DPH3 DPH2 | Gamma carboxylation, hypusine formation and arylsulfatase activation |
| GO:0017182 | 0.020283420769 | 0.666666666667 | DPH3 DPH2 | peptidyl-diphthamide metabolic process |
| GO:0017183 | 0.020283420769 | 0.666666666667 | DPH3 DPH2 | peptidyl-diphthamide biosynthetic process from peptidyl-histidine |
| GO:0002182 | 0.0378589948753 | 0.666666666667 | DPH3 DPH2 | cytoplasmic translational elongation |
| GO:0018202 | 0.0378589948753 | 0.666666666667 | DPH3 DPH2 | peptidyl-histidine modification |
| GO:1900247 | 0.0378589948753 | 0.666666666667 | DPH3 DPH2 | regulation of cytoplasmic translational elongation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DPH3 | SERGEF | 0.549 | 0.643 | bioplex (DPH3) bioplex_WMM |
| DPH2 | DPH3 | 0.034 | 0.259 | bioplex (DPH3) bioplex_WMM |
| DPH2 | SERGEF | 0.008 | 0.066 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05200 has an average edge precision of 0.323 which is ranked 4307 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DPH3 | HuMAP2_02058 HuMAP2_05200 |
| SERGEF | HuMAP2_02058 HuMAP2_05200 |
| DPH2 | HuMAP2_00850 HuMAP2_05200 HuMAP2_05568 |