hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05216
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MAT2B | Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) (Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase) | UniProt NCBI |
| RTRAF | RNA transcription, translation and transport factor protein (CLE7 homolog) (CLE) (hCLE) | UniProt NCBI |
| EFL1 | Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A) | UniProt NCBI |
| HNRNPM | Heterogeneous nuclear ribonucleoprotein M (hnRNP M) | UniProt NCBI |
| RTCB | tRNA-splicing ligase RtcB homolog (EC 6.5.1.3) | UniProt NCBI |
| FAM98B | Protein FAM98B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6301 | 2.25288169953e-08 | 0.5 | RTRAF FAM98B RTCB | tRNA Splicing Ligase Complex |
| GO:0072669 | 0.000101639975642 | 0.5 | RTRAF FAM98B RTCB | tRNA-splicing ligase complex |
| REAC:R-HSA-6784531 | 0.000146580428081 | 0.5 | RTRAF FAM98B RTCB | tRNA processing in the nucleus |
| GO:0006388 | 0.000660060925697 | 0.5 | RTRAF FAM98B RTCB | tRNA splicing, via endonucleolytic cleavage and ligation |
| GO:0000394 | 0.000824951429902 | 0.5 | RTRAF FAM98B RTCB | RNA splicing, via endonucleolytic cleavage and ligation |
| REAC:R-HSA-72306 | 0.00100731253956 | 0.5 | RTRAF FAM98B RTCB | tRNA processing |
| REAC:R-HSA-8953854 | 0.00833913786065 | 0.666666666667 | RTRAF FAM98B RTCB HNRNPM | Metabolism of RNA |
| CORUM:7191 | 0.0499726005494 | 0.166666666667 | MAT2B | Methionine adenosyltransferase alpha2 beta-v1 |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FAM98B | RTRAF | 0.919 | 0.842 | bioplex_WMM Guru gupta_WMM fraction |
| RTCB | HNRNPM | 0.723 | 0.733 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| RTCB | RTRAF | 0.441 | 0.584 | hein_WMM bioplex_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| HNRNPM | MAT2B | 0.427 | 0.576 | bioplex (MAT2B) fraction boldt_WMM treiber_WMM |
| HNRNPM | RTRAF | 0.296 | 0.495 | bioplex_WMM fraction treiber_WMM |
| HNRNPM | FAM98B | 0.084 | 0.347 | bioplex_WMM fraction treiber_WMM |
| FAM98B | EFL1 | 0.066 | 0.348 | youn_WMM fraction |
| RTCB | FAM98B | 0.027 | 0.232 | bioplex_WMM youn_WMM Malo gupta_WMM fraction treiber_WMM |
| RTCB | EFL1 | 0.017 | 0.171 | youn_WMM gupta_WMM fraction |
| RTRAF | EFL1 | 0.013 | 0.142 | gupta_WMM fraction |
| RTCB | MAT2B | 0.007 | 0.005 | bioplex (MAT2B) youn_WMM boldt_WMM treiber_WMM |
| MAT2B | RTRAF | 0.006 | 0.01 | bioplex (MAT2B) |
| HNRNPM | EFL1 | 0.0 | 0.013 | fraction treiber_WMM |
Images
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Complex HuMAP2_05216 has an average edge precision of 0.346 which is ranked 4046 out of all 6965 complexes.
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