hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05223
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| USF1 | Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1) | UniProt NCBI |
| HEATR6 | HEAT repeat-containing protein 6 (Amplified in breast cancer protein 1) | UniProt NCBI |
| USF2 | Upstream stimulatory factor 2 (Class B basic helix-loop-helix protein 12) (bHLHb12) (FOS-interacting protein) (FIP) (Major late transcription factor 2) (Upstream transcription factor 2) | UniProt NCBI |
| EIF1 | Eukaryotic translation initiation factor 1 (eIF1) (A121) (Protein translation factor SUI1 homolog) (Sui1iso1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6579 | 5.02777038712e-06 | 0.5 | USF2 USF1 | USF1-USF2 complex |
| GO:0000430 | 0.00270494046827 | 0.5 | USF2 USF1 | regulation of transcription from RNA polymerase II promoter by glucose |
| GO:0000432 | 0.00270494046827 | 0.5 | USF2 USF1 | positive regulation of transcription from RNA polymerase II promoter by glucose |
| GO:0046016 | 0.00270494046827 | 0.5 | USF2 USF1 | positive regulation of transcription by glucose |
| GO:0000429 | 0.00811409485621 | 0.5 | USF2 USF1 | carbon catabolite regulation of transcription from RNA polymerase II promoter |
| GO:0000436 | 0.00811409485621 | 0.5 | USF2 USF1 | carbon catabolite activation of transcription from RNA polymerase II promoter |
| GO:0045990 | 0.00811409485621 | 0.5 | USF2 USF1 | carbon catabolite regulation of transcription |
| GO:0045991 | 0.00811409485621 | 0.5 | USF2 USF1 | carbon catabolite activation of transcription |
| GO:0046015 | 0.00811409485621 | 0.5 | USF2 USF1 | regulation of transcription by glucose |
| GO:0019086 | 0.0162267366884 | 0.5 | USF2 USF1 | late viral transcription |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| USF1 | USF2 | 0.999 | 0.949 | hein_WMM bioplex (USF1) bioplex_WMM hein (USF1) |
| HEATR6 | EIF1 | 0.054 | 0.302 | fraction |
| USF1 | EIF1 | 0.049 | 0.296 | fraction |
| USF2 | HEATR6 | 0.0 | 0.015 | bioplex_WMM fraction |
| USF2 | EIF1 | 0.0 | 0.001 | fraction |
| USF1 | HEATR6 | 0.0 | 0.0 | fraction |
Images
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Complex HuMAP2_05223 has an average edge precision of 0.261 which is ranked 5220 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| USF1 | HuMAP2_04571 HuMAP2_05223 HuMAP2_05712 |
| HEATR6 | HuMAP2_05223 HuMAP2_05712 |
| USF2 | HuMAP2_04571 HuMAP2_05223 HuMAP2_06108 |
| EIF1 | HuMAP2_05223 HuMAP2_05712 |