hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05227
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CNOT2 | CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2) | UniProt NCBI |
| CNOT11 | CCR4-NOT transcription complex subunit 11 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6765 | 6.03332446455e-05 | 1.0 | CNOT2 CNOT11 | CCR4-NOT complex |
| CORUM:7192 | 6.03332446455e-05 | 1.0 | CNOT2 CNOT11 | CCR4-NOT-CNOT7-CNOT6 complex |
| CORUM:7214 | 6.03332446455e-05 | 1.0 | CNOT2 CNOT11 | CCR4-NOT-CNOT7-CNOT6L complex |
| CORUM:7215 | 6.03332446455e-05 | 1.0 | CNOT2 CNOT11 | CCR4-NOT-CNOT8-CNOT6 complex |
| CORUM:7216 | 6.03332446455e-05 | 1.0 | CNOT2 CNOT11 | CCR4-NOT-CNOT8-CNOT6L complex |
| REAC:R-HSA-6804115 | 0.000318425457851 | 1.0 | CNOT2 CNOT11 | TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain |
| REAC:R-HSA-429947 | 0.000502777038712 | 1.0 | CNOT2 CNOT11 | Deadenylation of mRNA |
| REAC:R-HSA-6791312 | 0.00189044166556 | 1.0 | CNOT2 CNOT11 | TP53 Regulates Transcription of Cell Cycle Genes |
| REAC:R-HSA-429914 | 0.00258092213206 | 1.0 | CNOT2 CNOT11 | Deadenylation-dependent mRNA decay |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CNOT2 | CNOT11 | 1.0 | 0.949 | hein_WMM youn (CNOT2) bioplex (CNOT11) bioplex_WMM boldt youn_WMM hein (CNOT2) gupta_WMM boldt_WMM |
Images
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Complex HuMAP2_05227 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CNOT2 | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 HuMAP2_05227 |
| CNOT11 | HuMAP2_00299 HuMAP2_01195 HuMAP2_01257 HuMAP2_05227 |