hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05228
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DDOST | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST 48 kDa subunit) (Oligosaccharyl transferase 48 kDa subunit) | UniProt NCBI |
| RPN1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1) | UniProt NCBI |
| RPN2 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (RIBIIR) (Ribophorin II) (RPN-II) (Ribophorin-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1199 | 4.50712536095e-09 | 1.0 | RPN1 DDOST RPN2 | Oligosaccharyltransferase complex (Stt3A variant) |
| CORUM:1200 | 7.88746938166e-09 | 1.0 | RPN1 DDOST RPN2 | Oligosaccharyltransferase complex (Stt3B variant) |
| CORUM:6131 | 2.70427521657e-08 | 1.0 | RPN1 DDOST RPN2 | SELK multiprotein complex |
| KEGG:00513 | 2.14716765829e-07 | 1.0 | RPN1 DDOST RPN2 | Various types of N-glycan biosynthesis |
| KEGG:00510 | 3.9827854995e-07 | 1.0 | RPN1 DDOST RPN2 | N-Glycan biosynthesis |
| GO:0004579 | 7.62876038594e-06 | 1.0 | RPN1 DDOST RPN2 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity |
| GO:0004576 | 1.08982291228e-05 | 1.0 | RPN1 DDOST RPN2 | oligosaccharyl transferase activity |
| GO:0008250 | 1.49850650438e-05 | 1.0 | RPN1 DDOST RPN2 | oligosaccharyltransferase complex |
| KEGG:04141 | 1.90270931244e-05 | 1.0 | RPN1 DDOST RPN2 | Protein processing in endoplasmic reticulum |
| REAC:R-HSA-1799339 | 9.97273388147e-05 | 1.0 | RPN1 DDOST RPN2 | SRP-dependent cotranslational protein targeting to membrane |
| GO:0018279 | 0.000368723418654 | 1.0 | RPN1 DDOST RPN2 | protein N-linked glycosylation via asparagine |
| GO:0018196 | 0.000408229499224 | 1.0 | RPN1 DDOST RPN2 | peptidyl-asparagine modification |
| REAC:R-HSA-446203 | 0.00171641263924 | 1.0 | RPN1 DDOST RPN2 | Asparagine N-linked glycosylation |
| WP:WP183 | 0.00175069745203 | 0.666666666667 | RPN1 RPN2 | Proteasome Degradation |
| REAC:R-HSA-72766 | 0.00180867442135 | 1.0 | RPN1 DDOST RPN2 | Translation |
| GO:0006487 | 0.00455146375597 | 1.0 | RPN1 DDOST RPN2 | protein N-linked glycosylation |
| KEGG:01100 | 0.0105851300972 | 1.0 | RPN1 DDOST RPN2 | Metabolic pathways |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RPN2 | DDOST | 0.998 | 0.944 | bioplex (RPN2) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| RPN2 | RPN1 | 0.94 | 0.853 | hein_WMM bioplex (RPN2) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| DDOST | RPN1 | 0.339 | 0.528 | hein_WMM bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_05228 has an average edge precision of 0.775 which is ranked 1016 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DDOST | HuMAP2_00906 HuMAP2_01092 HuMAP2_01521 HuMAP2_03276 HuMAP2_05228 HuMAP2_06982 |
| RPN1 | HuMAP2_01521 HuMAP2_03276 HuMAP2_03979 HuMAP2_05228 HuMAP2_05570 HuMAP2_06982 |
| RPN2 | HuMAP2_00485 HuMAP2_01092 HuMAP2_05228 HuMAP2_05631 HuMAP2_06974 |