hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05230
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SKIV2L | Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP) | UniProt NCBI |
| TTC37 | Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (SKI3 homolog) (Ski3) (Tricho-hepatic-enteric syndrome protein) (Thespin) | UniProt NCBI |
| UNC45A | Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1168 | 1.00675659188e-05 | 0.666666666667 | SKIV2L TTC37 | SKI complex |
| HP:0009886 | 0.000132571377575 | 0.666666666667 | SKIV2L TTC37 | Trichorrhexis nodosa |
| HP:0040130 | 0.000485986227107 | 0.666666666667 | SKIV2L TTC37 | Abnormal serum iron concentration |
| HP:0011031 | 0.000583157354768 | 0.666666666667 | SKIV2L TTC37 | Abnormality of iron homeostasis |
| REAC:R-HSA-429958 | 0.000802944115303 | 0.666666666667 | SKIV2L TTC37 | mRNA decay by 3' to 5' exoribonuclease |
| HP:0011472 | 0.00120138848745 | 0.666666666667 | SKIV2L TTC37 | Abnormality of small intestinal villus morphology |
| HP:0011473 | 0.00120138848745 | 0.666666666667 | SKIV2L TTC37 | Villous atrophy |
| KEGG:03018 | 0.00127210962765 | 0.666666666667 | SKIV2L TTC37 | RNA degradation |
| HP:0011030 | 0.00135150150266 | 0.666666666667 | SKIV2L TTC37 | Abnormal blood transition element cation concentration |
| HP:0002224 | 0.0015104340107 | 0.666666666667 | SKIV2L TTC37 | Woolly hair |
| HP:0003328 | 0.00309925335629 | 0.666666666667 | SKIV2L TTC37 | Abnormal hair laboratory examination |
| GO:0055087 | 0.00405722906526 | 0.666666666667 | SKIV2L TTC37 | Ski complex |
| HP:0002299 | 0.00620427636329 | 0.666666666667 | SKIV2L TTC37 | Brittle hair |
| REAC:R-HSA-429914 | 0.0102859860332 | 0.666666666667 | SKIV2L TTC37 | Deadenylation-dependent mRNA decay |
| HP:0000445 | 0.029972334664 | 0.666666666667 | SKIV2L TTC37 | Wide nose |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SKIV2L | TTC37 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
| SKIV2L | UNC45A | 0.281 | 0.487 | bioplex_WMM gupta_WMM fraction |
| UNC45A | TTC37 | 0.034 | 0.261 | bioplex_WMM gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_05230 has an average edge precision of 0.566 which is ranked 2104 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SKIV2L | HuMAP2_00385 HuMAP2_05230 HuMAP2_06349 HuMAP2_06992 |
| TTC37 | HuMAP2_05230 HuMAP2_06349 HuMAP2_06992 |
| UNC45A | HuMAP2_00385 HuMAP2_05230 HuMAP2_06349 |