hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05233
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TALDO1 | Transaldolase (EC 2.2.1.2) | UniProt NCBI |
| NT5DC1 | 5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-) | UniProt NCBI |
| HDDC3 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase) | UniProt NCBI |
| GLA | Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Melibiase) (Agalsidase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6791462 | 0.0499190562503 | 0.25 | TALDO1 | TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P |
| REAC:R-HSA-6791055 | 0.0499190562503 | 0.25 | TALDO1 | TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NT5DC1 | TALDO1 | 0.294 | 0.495 | bioplex (NT5DC1) bioplex_WMM fraction treiber_WMM |
| HDDC3 | TALDO1 | 0.053 | 0.301 | fraction |
| TALDO1 | GLA | 0.045 | 0.281 | bioplex (TALDO1) bioplex_WMM fraction |
| NT5DC1 | GLA | 0.007 | 0.005 | bioplex (NT5DC1) bioplex_WMM |
Images
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Complex HuMAP2_05233 has an average edge precision of 0.271 which is ranked 5016 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TALDO1 | HuMAP2_00823 HuMAP2_02686 HuMAP2_05233 HuMAP2_05571 |
| NT5DC1 | HuMAP2_00053 HuMAP2_02627 HuMAP2_02765 HuMAP2_05050 HuMAP2_05233 |
| HDDC3 | HuMAP2_00269 HuMAP2_00327 HuMAP2_01744 HuMAP2_01973 HuMAP2_02637 HuMAP2_03180 HuMAP2_05233 HuMAP2_05571 HuMAP2_06557 |
| GLA | HuMAP2_03982 HuMAP2_05233 |