hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05251
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MT-CO1 | Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I) | UniProt NCBI |
| CD63 | CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63) | UniProt NCBI |
| RETREG3 | Reticulophagy regulator 3 | UniProt NCBI |
| CERS6 | Ceramide synthase 6 (CerS6) (LAG1 longevity assurance homolog 6) | UniProt NCBI |
| PLSCR1 | Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2153 | 0.0499494897235 | 0.2 | CD63 | ITGAM-ITGB2-CD11 complex |
| CORUM:6410 | 0.0499494897235 | 0.2 | MT-CO1 | MITRAC7-COX1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PLSCR1 | RETREG3 | 0.631 | 0.681 | bioplex (RETREG3) bioplex_WMM |
| RETREG3 | MT-CO1 | 0.176 | 0.435 | bioplex (RETREG3) bioplex_WMM |
| RETREG3 | CD63 | 0.093 | 0.355 | bioplex (RETREG3) bioplex_WMM |
| RETREG3 | CERS6 | 0.073 | 0.355 | bioplex (RETREG3) bioplex_WMM |
| PLSCR1 | CD63 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| MT-CO1 | CERS6 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| PLSCR1 | CERS6 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| PLSCR1 | MT-CO1 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| CD63 | CERS6 | 0.006 | 0.009 | bioplex_WMM WMM_only |
| CD63 | MT-CO1 | 0.006 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05251 has an average edge precision of 0.186 which is ranked 6366 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MT-CO1 | HuMAP2_04240 HuMAP2_05251 HuMAP2_05460 |
| CD63 | HuMAP2_04240 HuMAP2_05251 |
| RETREG3 | HuMAP2_03415 HuMAP2_04240 HuMAP2_05251 |
| CERS6 | HuMAP2_04240 HuMAP2_04868 HuMAP2_05251 |
| PLSCR1 | HuMAP2_00077 HuMAP2_02998 HuMAP2_03171 HuMAP2_03415 HuMAP2_04240 HuMAP2_05251 |