hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05256
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PAG1 | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane adapter protein PAG) (Transmembrane phosphoprotein Cbp) | UniProt NCBI |
| CLPB | Caseinolytic peptidase B protein homolog (EC 3.6.1.3) (Suppressor of potassium transport defect 3) | UniProt NCBI |
| HAX1 | HCLS1-associated protein X-1 (HS1-associating protein X-1) (HAX-1) (HS1-binding protein 1) (HSP1BP-1) | UniProt NCBI |
| MAP1LC3A | Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (MAP1A/MAP1B light chain 3 A) (MAP1A/MAP1B LC3 A) (Microtubule-associated protein 1 light chain 3 alpha) | UniProt NCBI |
| ICA1 | Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-4703-3p | 0.0282835942562 | 0.4 | PAG1 CLPB | hsa-miR-4703-3p |
| MIRNA:hsa-miR-299-5p | 0.0435496282017 | 0.4 | CLPB HAX1 | hsa-miR-299-5p |
| CORUM:6292 | 0.0499494897235 | 0.2 | HAX1 | HAX-1-XIAP complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CLPB | HAX1 | 0.857 | 0.795 | hein_WMM bioplex (CLPB,HAX1) bioplex_WMM boldt youn_WMM hein (HAX1) boldt_WMM |
| ICA1 | CLPB | 0.5 | 0.621 | bioplex (CLPB) bioplex_WMM |
| MAP1LC3A | HAX1 | 0.337 | 0.526 | bioplex (HAX1) bioplex_WMM |
| CLPB | PAG1 | 0.06 | 0.333 | bioplex (CLPB) bioplex_WMM |
| ICA1 | PAG1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| ICA1 | HAX1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| MAP1LC3A | CLPB | 0.007 | 0.007 | bioplex_WMM WMM_only |
| HAX1 | PAG1 | 0.007 | 0.008 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05256 has an average edge precision of 0.288 which is ranked 4774 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PAG1 | HuMAP2_04281 HuMAP2_05256 HuMAP2_06873 |
| CLPB | HuMAP2_01046 HuMAP2_04281 HuMAP2_04564 HuMAP2_05256 HuMAP2_06873 |
| HAX1 | HuMAP2_01046 HuMAP2_01976 HuMAP2_04564 HuMAP2_05256 HuMAP2_06873 |
| MAP1LC3A | HuMAP2_00241 HuMAP2_01976 HuMAP2_05256 HuMAP2_06873 |
| ICA1 | HuMAP2_00559 HuMAP2_04281 HuMAP2_04564 HuMAP2_05256 HuMAP2_06534 HuMAP2_06873 |