hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05257
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| LDHC | L-lactate dehydrogenase C chain (LDH-C) (EC 1.1.1.27) (Cancer/testis antigen 32) (CT32) (LDH testis subunit) (LDH-X) | UniProt NCBI |
| LDHAL6B | L-lactate dehydrogenase A-like 6B (EC 1.1.1.27) | UniProt NCBI |
| ADSL | Adenylosuccinate lyase (ADSL) (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00640 | 0.000250877114117 | 0.666666666667 | LDHC LDHAL6B | Propanoate metabolism |
| KEGG:00620 | 0.00033129816608 | 0.666666666667 | LDHC LDHAL6B | Pyruvate metabolism |
| KEGG:00270 | 0.000462599152438 | 0.666666666667 | LDHC LDHAL6B | Cysteine and methionine metabolism |
| KEGG:00010 | 0.00087223886567 | 0.666666666667 | LDHC LDHAL6B | Glycolysis / Gluconeogenesis |
| WP:WP534 | 0.000905695914221 | 0.666666666667 | LDHC LDHAL6B | Glycolysis and Gluconeogenesis |
| KEGG:05230 | 0.000987288198645 | 0.666666666667 | LDHC LDHAL6B | Central carbon metabolism in cancer |
| KEGG:04922 | 0.00203354700377 | 0.666666666667 | LDHC LDHAL6B | Glucagon signaling pathway |
| KEGG:04066 | 0.00220707183162 | 0.666666666667 | LDHC LDHAL6B | HIF-1 signaling pathway |
| REAC:R-HSA-70268 | 0.00271504560844 | 0.666666666667 | LDHC LDHAL6B | Pyruvate metabolism |
| REAC:R-HSA-71406 | 0.008858224502 | 0.666666666667 | LDHC LDHAL6B | Pyruvate metabolism and Citric Acid (TCA) cycle |
| KEGG:01100 | 0.0105851300972 | 1.0 | LDHC ADSL LDHAL6B | Metabolic pathways |
| GO:0004459 | 0.0283955176165 | 0.666666666667 | LDHC LDHAL6B | L-lactate dehydrogenase activity |
| GO:0004457 | 0.0378589948753 | 0.666666666667 | LDHC LDHAL6B | lactate dehydrogenase activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ADSL | LDHAL6B | 0.754 | 0.748 | fraction |
| ADSL | LDHC | 0.743 | 0.739 | fraction |
Images
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Complex HuMAP2_05257 has an average edge precision of 0.744 which is ranked 1188 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| LDHC | HuMAP2_05257 HuMAP2_05316 HuMAP2_06767 |
| LDHAL6B | HuMAP2_05257 HuMAP2_05943 HuMAP2_06781 |
| ADSL | HuMAP2_00869 HuMAP2_03277 HuMAP2_04245 HuMAP2_05257 HuMAP2_06767 |