hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05258
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CASTOR2 | Cytosolic arginine sensor for mTORC1 subunit 2 (Cellular arginine sensor for mTORC1 protein 2) (GATS-like protein 2) | UniProt NCBI |
| CASTOR1 | Cytosolic arginine sensor for mTORC1 subunit 1 (Cellular arginine sensor for mTORC1 protein 1) (GATS-like protein 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1903576 | 0.00135247023414 | 1.0 | CASTOR1 CASTOR2 | response to L-arginine |
| GO:1903577 | 0.00135247023414 | 1.0 | CASTOR1 CASTOR2 | cellular response to L-arginine |
| KEGG:04150 | 0.00150216111442 | 1.0 | CASTOR1 CASTOR2 | mTOR signaling pathway |
| GO:0061700 | 0.029754345151 | 1.0 | CASTOR1 CASTOR2 | GATOR2 complex |
| GO:1904262 | 0.0410249304355 | 1.0 | CASTOR1 CASTOR2 | negative regulation of TORC1 signaling |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CASTOR1 | CASTOR2 | 0.998 | 0.943 | bioplex (CASTOR1) bioplex_WMM |
Images
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Complex HuMAP2_05258 has an average edge precision of 0.943 which is ranked 373 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CASTOR2 | HuMAP2_03326 HuMAP2_05258 HuMAP2_06647 |
| CASTOR1 | HuMAP2_03326 HuMAP2_05258 HuMAP2_06647 HuMAP2_06753 |