hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05261
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GGNBP2 | Gametogenetin-binding protein 2 (Laryngeal carcinoma-related protein 1) (Protein ZNF403) | UniProt NCBI |
| ZNF331 | Zinc finger protein 331 (C2H2-like zinc finger protein rearranged in thyroid adenomas) (Zinc finger protein 361) (Zinc finger protein 463) | UniProt NCBI |
| LRP4 | Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) | UniProt NCBI |
| CEP78 | Centrosomal protein of 78 kDa (Cep78) | UniProt NCBI |
| ALKBH6 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 6) | UniProt NCBI |
| FBXO38 | F-box only protein 38 | UniProt NCBI |
| FAM172A | Cotranscriptional regulator FAM172A (Protein FAM172A) | UniProt NCBI |
| LTBP4 | Latent-transforming growth factor beta-binding protein 4 (LTBP-4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0031108 | 0.0173789434513 | 0.25 | LRP4 FBXO38 | Triceps weakness |
| HP:0009005 | 0.0253031982095 | 0.25 | LRP4 FBXO38 | Weakness of the intrinsic hand muscles |
| HP:0003701 | 0.0455379837347 | 0.375 | LTBP4 LRP4 FBXO38 | Proximal muscle weakness |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZNF331 | GGNBP2 | 0.068 | 0.348 | bioplex (ZNF331) bioplex_WMM |
| ZNF331 | LRP4 | 0.037 | 0.264 | bioplex (ZNF331) bioplex_WMM |
| ZNF331 | FAM172A | 0.036 | 0.265 | bioplex (ZNF331) bioplex_WMM |
| ZNF331 | FBXO38 | 0.035 | 0.264 | bioplex (ZNF331) bioplex_WMM |
| ZNF331 | CEP78 | 0.027 | 0.23 | bioplex (ZNF331) bioplex_WMM |
| ZNF331 | LTBP4 | 0.024 | 0.215 | bioplex (ZNF331) bioplex_WMM |
| FAM172A | ALKBH6 | 0.024 | 0.214 | fraction |
| FAM172A | FBXO38 | 0.014 | 0.144 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| GGNBP2 | LRP4 | 0.008 | 0.084 | bioplex_WMM WMM_only |
| GGNBP2 | LTBP4 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| GGNBP2 | FBXO38 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| LRP4 | LTBP4 | 0.008 | 0.025 | bioplex_WMM WMM_only |
| FAM172A | GGNBP2 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| LRP4 | FBXO38 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| FBXO38 | LTBP4 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| FAM172A | LRP4 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| FAM172A | LTBP4 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| CEP78 | FBXO38 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| CEP78 | GGNBP2 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| FAM172A | CEP78 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| CEP78 | LRP4 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| CEP78 | LTBP4 | 0.006 | 0.008 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05261 has an average edge precision of 0.102 which is ranked 6930 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GGNBP2 | HuMAP2_01082 HuMAP2_02673 HuMAP2_04155 HuMAP2_05261 |
| ZNF331 | HuMAP2_00200 HuMAP2_01082 HuMAP2_05261 |
| LRP4 | HuMAP2_03202 HuMAP2_05261 HuMAP2_06369 |
| CEP78 | HuMAP2_00618 HuMAP2_03772 HuMAP2_05261 |
| ALKBH6 | HuMAP2_01614 HuMAP2_03934 HuMAP2_05261 HuMAP2_06340 HuMAP2_06548 |
| FBXO38 | HuMAP2_04541 HuMAP2_05261 |
| FAM172A | HuMAP2_00573 HuMAP2_01614 HuMAP2_03934 HuMAP2_05261 HuMAP2_06340 |
| LTBP4 | HuMAP2_05088 HuMAP2_05261 HuMAP2_05834 |