hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05268
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KCTD1 | BTB/POZ domain-containing protein KCTD1 (Potassium channel tetramerization domain-containing protein 1) | UniProt NCBI |
| KCTD3 | BTB/POZ domain-containing protein KCTD3 (Renal carcinoma antigen NY-REN-45) | UniProt NCBI |
| KCTD15 | BTB/POZ domain-containing protein KCTD15 (Potassium channel tetramerization domain-containing protein 15) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8866904 | 0.000240958766872 | 0.666666666667 | KCTD15 KCTD1 | Negative regulation of activity of TFAP2 (AP-2) family transcription factors |
| REAC:R-HSA-8864260 | 0.00271504560844 | 0.666666666667 | KCTD15 KCTD1 | Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KCTD3 | KCTD1 | 0.714 | 0.728 | bioplex (KCTD3) bioplex_WMM |
| KCTD3 | KCTD15 | 0.554 | 0.646 | bioplex (KCTD3) bioplex_WMM |
| KCTD15 | KCTD1 | 0.008 | 0.067 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05268 has an average edge precision of 0.48 which is ranked 2637 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KCTD1 | HuMAP2_00381 HuMAP2_02638 HuMAP2_05268 HuMAP2_06500 |
| KCTD3 | HuMAP2_00381 HuMAP2_02638 HuMAP2_05268 HuMAP2_06500 |
| KCTD15 | HuMAP2_00381 HuMAP2_02638 HuMAP2_04791 HuMAP2_05268 |