hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_05277
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RHOT2 | Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2) | UniProt NCBI |
| RHOT1 | Mitochondrial Rho GTPase 1 (MIRO-1) (hMiro-1) (EC 3.6.5.-) (Rac-GTP-binding protein-like protein) (Ras homolog gene family member T1) | UniProt NCBI |
| UBC | Polyubiquitin-C [Cleaved into: Ubiquitin] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04137 | 0.000844586654193 | 0.666666666667 | RHOT1 RHOT2 | Mitophagy - animal |
| GO:0005741 | 0.0268132763851 | 1.0 | RHOT1 UBC RHOT2 | mitochondrial outer membrane |
| GO:0031968 | 0.0340260876928 | 1.0 | RHOT1 UBC RHOT2 | organelle outer membrane |
| GO:0019867 | 0.0348113051011 | 1.0 | RHOT1 UBC RHOT2 | outer membrane |
| CORUM:5832 | 0.0499776345577 | 0.333333333333 | RHOT2 | PINK1-MIRO2-Milton complex |
| CORUM:5836 | 0.0499776345577 | 0.333333333333 | RHOT2 | MIRO2-Milton complex |
| CORUM:7346 | 0.0499776345577 | 0.333333333333 | RHOT1 | DISC1-RHOT1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RHOT2 | UBC | 1.0 | 0.949 | bioplex (RHOT2) bioplex_WMM |
| RHOT2 | RHOT1 | 0.08 | 0.352 | bioplex (RHOT2) bioplex_WMM |
| UBC | RHOT1 | 0.007 | 0.01 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_05277 has an average edge precision of 0.437 which is ranked 2959 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RHOT2 | HuMAP2_00291 HuMAP2_05277 |
| RHOT1 | HuMAP2_01718 HuMAP2_03894 HuMAP2_04384 HuMAP2_05277 |
| UBC | HuMAP2_00291 HuMAP2_05277 |