hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05278
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ZRSR2 | U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (Renal carcinoma antigen NY-REN-20) (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (U2AF35-related protein) (URP) | UniProt NCBI |
| RNPC3 | RNA-binding region-containing protein 3 (RNA-binding motif protein 40) (RNA-binding protein 40) (U11/U12 small nuclear ribonucleoprotein 65 kDa protein) (U11/U12 snRNP 65 kDa protein) (U11/U12-65K) | UniProt NCBI |
| SNRNP35 | U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U11/U12-35K) (Protein HM-1) (U1 snRNP-binding protein homolog) | UniProt NCBI |
| ZMAT5 | Zinc finger matrin-type protein 5 (U11/U12 small nuclear ribonucleoprotein 20 kDa protein) (U11/U12 snRNP 20 kDa protein) (U11/U12-20K) | UniProt NCBI |
| ZRSR2P1 | NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:430 | 4.81835009157e-10 | 1.0 | SNRNP35 ZRSR2 ZMAT5 RNPC3 | 18S U11/U12 snRNP |
| REAC:R-HSA-72165 | 2.455200129e-08 | 1.0 | SNRNP35 ZRSR2 ZMAT5 RNPC3 | mRNA Splicing - Minor Pathway |
| GO:0005689 | 3.08603851103e-07 | 1.0 | SNRNP35 ZRSR2 ZMAT5 RNPC3 | U12-type spliceosomal complex |
| REAC:R-HSA-72172 | 4.37825325788e-06 | 1.0 | SNRNP35 ZRSR2 ZMAT5 RNPC3 | mRNA Splicing |
| REAC:R-HSA-72203 | 1.12324610099e-05 | 1.0 | SNRNP35 ZRSR2 ZMAT5 RNPC3 | Processing of Capped Intron-Containing Pre-mRNA |
| GO:0005681 | 0.000657808747052 | 1.0 | SNRNP35 ZRSR2 ZMAT5 RNPC3 | spliceosomal complex |
| REAC:R-HSA-8953854 | 0.000676603019954 | 1.0 | SNRNP35 ZRSR2 ZMAT5 RNPC3 | Metabolism of RNA |
| GO:0000377 | 0.00944788787297 | 1.0 | SNRNP35 ZRSR2 ZMAT5 RNPC3 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| GO:0000398 | 0.00944788787297 | 1.0 | SNRNP35 ZRSR2 ZMAT5 RNPC3 | mRNA splicing, via spliceosome |
| GO:0000375 | 0.00981835447646 | 1.0 | SNRNP35 ZRSR2 ZMAT5 RNPC3 | RNA splicing, via transesterification reactions |
| GO:0008380 | 0.0187431053955 | 1.0 | SNRNP35 ZRSR2 ZMAT5 RNPC3 | RNA splicing |
| GO:0006397 | 0.0251226492241 | 1.0 | SNRNP35 ZRSR2 ZMAT5 RNPC3 | mRNA processing |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZRSR2P1 | ZRSR2 | 1.0 | 0.949 | bioplex (ZRSR2) bioplex_WMM |
| ZRSR2 | ZMAT5 | 0.995 | 0.923 | bioplex (ZRSR2) bioplex_WMM |
| ZRSR2 | SNRNP35 | 0.989 | 0.905 | bioplex (ZRSR2) bioplex_WMM |
| ZRSR2 | RNPC3 | 0.824 | 0.773 | bioplex (ZRSR2) bioplex_WMM |
| SNRNP35 | RNPC3 | 0.063 | 0.347 | bioplex (SNRNP35) bioplex_WMM youn_WMM |
| ZMAT5 | RNPC3 | 0.054 | 0.299 | bioplex (ZMAT5) bioplex_WMM |
| SNRNP35 | ZMAT5 | 0.051 | 0.301 | bioplex (ZMAT5) bioplex_WMM |
| ZRSR2P1 | ZMAT5 | 0.018 | 0.179 | bioplex (ZMAT5) bioplex_WMM |
| ZRSR2P1 | SNRNP35 | 0.012 | 0.149 | bioplex_WMM WMM_only |
| ZRSR2P1 | RNPC3 | 0.012 | 0.149 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05278 has an average edge precision of 0.497 which is ranked 2514 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ZRSR2 | HuMAP2_01062 HuMAP2_01898 HuMAP2_02518 HuMAP2_04425 HuMAP2_05278 |
| RNPC3 | HuMAP2_01062 HuMAP2_02518 HuMAP2_04425 HuMAP2_05278 |
| SNRNP35 | HuMAP2_01062 HuMAP2_02518 HuMAP2_04425 HuMAP2_05278 |
| ZMAT5 | HuMAP2_01062 HuMAP2_02518 HuMAP2_04425 HuMAP2_05278 |
| ZRSR2P1 | HuMAP2_00440 HuMAP2_01062 HuMAP2_01898 HuMAP2_05278 HuMAP2_06542 |