hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05280
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GINS2 | DNA replication complex GINS protein PSF2 (GINS complex subunit 2) | UniProt NCBI |
| GINS1 | DNA replication complex GINS protein PSF1 (GINS complex subunit 1) | UniProt NCBI |
| GINS4 | DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:678 | 9.0142507219e-10 | 1.0 | GINS1 GINS4 GINS2 | GINS complex |
| GO:0000811 | 9.08185760231e-08 | 1.0 | GINS1 GINS4 GINS2 | GINS complex |
| REAC:R-HSA-176974 | 9.89113204212e-08 | 1.0 | GINS1 GINS4 GINS2 | Unwinding of DNA |
| GO:0031261 | 9.08185760231e-07 | 1.0 | GINS1 GINS4 GINS2 | DNA replication preinitiation complex |
| REAC:R-HSA-69190 | 2.23000067859e-06 | 1.0 | GINS1 GINS4 GINS2 | DNA strand elongation |
| GO:0043138 | 3.30579616724e-05 | 1.0 | GINS1 GINS4 GINS2 | 3'-5' DNA helicase activity |
| GO:0006271 | 6.17566316957e-05 | 1.0 | GINS1 GINS4 GINS2 | DNA strand elongation involved in DNA replication |
| REAC:R-HSA-69239 | 0.000120004609098 | 1.0 | GINS1 GINS4 GINS2 | Synthesis of DNA |
| REAC:R-HSA-69306 | 0.000146343794532 | 1.0 | GINS1 GINS4 GINS2 | DNA Replication |
| GO:0022616 | 0.000183816797871 | 1.0 | GINS1 GINS4 GINS2 | DNA strand elongation |
| REAC:R-HSA-69242 | 0.000295546575822 | 1.0 | GINS1 GINS4 GINS2 | S Phase |
| GO:0003678 | 0.00265735153444 | 1.0 | GINS1 GINS4 GINS2 | DNA helicase activity |
| REAC:R-HSA-69278 | 0.0102351006549 | 1.0 | GINS1 GINS4 GINS2 | Cell Cycle, Mitotic |
| GO:0004386 | 0.0106693663112 | 1.0 | GINS1 GINS4 GINS2 | helicase activity |
| GO:0008094 | 0.011404996777 | 1.0 | GINS1 GINS4 GINS2 | DNA-dependent ATPase activity |
| REAC:R-HSA-1640170 | 0.0176005573074 | 1.0 | GINS1 GINS4 GINS2 | Cell Cycle |
| GO:0006261 | 0.0302766427817 | 1.0 | GINS1 GINS4 GINS2 | DNA-dependent DNA replication |
| GO:0031298 | 0.0378589948753 | 0.666666666667 | GINS2 GINS4 | replication fork protection complex |
| GO:0032993 | 0.0380729634404 | 1.0 | GINS1 GINS4 GINS2 | protein-DNA complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GINS1 | GINS4 | 1.0 | 0.949 | bioplex_WMM Malo fraction |
| GINS1 | GINS2 | 1.0 | 0.949 | bioplex_WMM youn_WMM Malo fraction |
| GINS4 | GINS2 | 0.66 | 0.697 | bioplex_WMM Malo fraction |
Images
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Complex HuMAP2_05280 has an average edge precision of 0.865 which is ranked 703 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GINS2 | HuMAP2_01803 HuMAP2_03617 HuMAP2_03710 HuMAP2_05280 |
| GINS1 | HuMAP2_01803 HuMAP2_03617 HuMAP2_03710 HuMAP2_05280 |
| GINS4 | HuMAP2_01803 HuMAP2_02711 HuMAP2_03617 HuMAP2_03710 HuMAP2_05280 |