hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05301
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KAT6B | Histone acetyltransferase KAT6B (EC 2.3.1.48) (Histone acetyltransferase MOZ2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (MYST-4) (Monocytic leukemia zinc finger protein-related factor) | UniProt NCBI |
| MEAF6 | Chromatin modification-related protein MEAF6 (MYST/Esa1-associated factor 6) (Esa1-associated factor 6 homolog) (Protein EAF6 homolog) (hEAF6) (Sarcoma antigen NY-SAR-91) | UniProt NCBI |
| JADE3 | Protein Jade-3 (Jade family PHD finger protein 3) (PHD finger protein 16) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7255 | 2.01342304124e-05 | 0.666666666667 | JADE3 MEAF6 | ING5 complex (ING5, JADE3, KAT7, MEAF6) |
| CORUM:2848 | 2.01342304124e-05 | 0.666666666667 | JADE3 MEAF6 | ING4 complex (ING4, JADE3, KAT7, MEAF6) |
| CORUM:7252 | 3.35555483123e-05 | 0.666666666667 | MEAF6 KAT6B | ING5 (BRPF2, MOZ, MORF) complex |
| CORUM:2859 | 3.35555483123e-05 | 0.666666666667 | MEAF6 KAT6B | ING5 (BRPF1, MOZ, MORF) complex |
| CORUM:7253 | 3.35555483123e-05 | 0.666666666667 | MEAF6 KAT6B | ING5 (BRPF3, MOZ, MORF) complex |
| REAC:R-HSA-3214847 | 0.000210042684884 | 1.0 | JADE3 KAT6B MEAF6 | HATs acetylate histones |
| REAC:R-HSA-4839726 | 0.00144234915262 | 1.0 | JADE3 KAT6B MEAF6 | Chromatin organization |
| REAC:R-HSA-3247509 | 0.00144234915262 | 1.0 | JADE3 KAT6B MEAF6 | Chromatin modifying enzymes |
| GO:0043966 | 0.00178004409005 | 1.0 | JADE3 KAT6B MEAF6 | histone H3 acetylation |
| GO:0000123 | 0.00690911398953 | 1.0 | JADE3 KAT6B MEAF6 | histone acetyltransferase complex |
| GO:1902493 | 0.00996606725847 | 1.0 | JADE3 KAT6B MEAF6 | acetyltransferase complex |
| GO:0031248 | 0.00996606725847 | 1.0 | JADE3 KAT6B MEAF6 | protein acetyltransferase complex |
| GO:0016573 | 0.0180261250619 | 1.0 | JADE3 KAT6B MEAF6 | histone acetylation |
| GO:0018393 | 0.0190659069388 | 1.0 | JADE3 KAT6B MEAF6 | internal peptidyl-lysine acetylation |
| GO:0043983 | 0.020283420769 | 0.666666666667 | JADE3 MEAF6 | histone H4-K12 acetylation |
| GO:0006475 | 0.0218385980648 | 1.0 | JADE3 KAT6B MEAF6 | internal protein amino acid acetylation |
| GO:0018394 | 0.022423560513 | 1.0 | JADE3 KAT6B MEAF6 | peptidyl-lysine acetylation |
| GO:0070776 | 0.0283955176165 | 0.666666666667 | MEAF6 KAT6B | MOZ/MORF histone acetyltransferase complex |
| GO:0070775 | 0.0283955176165 | 0.666666666667 | MEAF6 KAT6B | H3 histone acetyltransferase complex |
| GO:0006473 | 0.047104416733 | 1.0 | JADE3 KAT6B MEAF6 | protein acetylation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MEAF6 | JADE3 | 0.947 | 0.857 | hein_WMM bioplex (MEAF6) bioplex_WMM |
| MEAF6 | KAT6B | 0.623 | 0.678 | bioplex (MEAF6) bioplex_WMM |
| KAT6B | JADE3 | 0.008 | 0.091 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05301 has an average edge precision of 0.542 which is ranked 2254 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KAT6B | HuMAP2_01906 HuMAP2_05301 HuMAP2_06383 |
| MEAF6 | HuMAP2_01817 HuMAP2_01906 HuMAP2_03532 HuMAP2_03860 HuMAP2_05301 HuMAP2_06383 HuMAP2_06741 |
| JADE3 | HuMAP2_03532 HuMAP2_05301 HuMAP2_06324 HuMAP2_06383 |