hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_05315
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SEC13 | Protein SEC13 homolog (GATOR complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein) | UniProt NCBI |
| SEH1L | Nucleoporin SEH1 (GATOR complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein) | UniProt NCBI |
| NUP85 | Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup75) (Nucleoporin Nup85) (Pericentrin-1) | UniProt NCBI |
| NUP160 | Nuclear pore complex protein Nup160 (160 kDa nucleoporin) (Nucleoporin Nup160) | UniProt NCBI |
| NUP43 | Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42) | UniProt NCBI |
| NUP107 | Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107) | UniProt NCBI |
| NUP37 | Nucleoporin Nup37 (p37) (Nup107-160 subcomplex subunit Nup37) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:87 | 5.94440197731e-23 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | Nup 107-160 subcomplex |
| GO:0031080 | 1.86257928622e-19 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nuclear pore outer ring |
| GO:0071431 | 6.63085676213e-15 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | tRNA-containing ribonucleoprotein complex export from nucleus |
| GO:0006409 | 6.63085676213e-15 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | tRNA export from nucleus |
| GO:0051031 | 1.04374597182e-14 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | tRNA transport |
| GO:0097064 | 1.59801107409e-14 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | ncRNA export from nucleus |
| REAC:R-HSA-168274 | 2.90797053641e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Export of Viral Ribonucleoproteins from Nucleus |
| REAC:R-HSA-5619107 | 2.90797053641e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) |
| REAC:R-HSA-168271 | 2.90797053641e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Transport of Ribonucleoproteins into the Host Nucleus |
| REAC:R-HSA-168333 | 2.90797053641e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | NEP/NS2 Interacts with the Cellular Export Machinery |
| REAC:R-HSA-170822 | 2.90797053641e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Regulation of Glucokinase by Glucokinase Regulatory Protein |
| REAC:R-HSA-180746 | 4.58268602674e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Nuclear import of Rev protein |
| REAC:R-HSA-180910 | 4.58268602674e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Vpr-mediated nuclear import of PICs |
| REAC:R-HSA-159227 | 4.58268602674e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Transport of the SLBP independent Mature mRNA |
| REAC:R-HSA-165054 | 5.68220306165e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Rev-mediated nuclear export of HIV RNA |
| REAC:R-HSA-4085377 | 5.68220306165e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | SUMOylation of SUMOylation proteins |
| REAC:R-HSA-159230 | 5.68220306165e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Transport of the SLBP Dependant Mature mRNA |
| REAC:R-HSA-3301854 | 6.99307747711e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Nuclear Pore Complex (NPC) Disassembly |
| REAC:R-HSA-177243 | 8.54660187695e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Interactions of Rev with host cellular proteins |
| REAC:R-HSA-176033 | 8.54660187695e-14 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Interactions of Vpr with host cellular proteins |
| REAC:R-HSA-3232142 | 1.03774181439e-13 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | SUMOylation of ubiquitinylation proteins |
| REAC:R-HSA-168276 | 1.79351701411e-13 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | NS1 Mediated Effects on Host Pathways |
| REAC:R-HSA-159231 | 1.79351701411e-13 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Transport of Mature mRNA Derived from an Intronless Transcript |
| REAC:R-HSA-159234 | 2.12967861653e-13 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Transport of Mature mRNAs Derived from Intronless Transcripts |
| REAC:R-HSA-168253 | 2.12967861653e-13 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Host Interactions with Influenza Factors |
| GO:0075733 | 2.74886528862e-13 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | intracellular transport of virus |
| REAC:R-HSA-168325 | 2.96070890203e-13 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Viral Messenger RNA Synthesis |
| REAC:R-HSA-4570464 | 4.04583533895e-13 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | SUMOylation of RNA binding proteins |
| REAC:R-HSA-4615885 | 4.04583533895e-13 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | SUMOylation of DNA replication proteins |
| GO:0046794 | 4.10366318087e-13 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | transport of virus |
| KEGG:03013 | 5.51217700869e-13 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | RNA transport |
| REAC:R-HSA-2980766 | 6.28082580629e-13 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Nuclear Envelope Breakdown |
| GO:0006110 | 9.64220342905e-13 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of glycolytic process |
| REAC:R-HSA-191859 | 1.22501151933e-12 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | snRNP Assembly |
| REAC:R-HSA-194441 | 1.22501151933e-12 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Metabolism of non-coding RNA |
| GO:1902579 | 1.67460972174e-12 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | multi-organism localization |
| GO:0043470 | 1.67460972174e-12 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of carbohydrate catabolic process |
| GO:0044766 | 1.67460972174e-12 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | multi-organism transport |
| REAC:R-HSA-6784531 | 1.99055233916e-12 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | tRNA processing in the nucleus |
| GO:1900034 | 3.39329257683e-12 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of cellular response to heat |
| GO:0005643 | 3.73262183452e-12 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nuclear pore |
| REAC:R-HSA-3371453 | 6.36202152662e-12 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Regulation of HSF1-mediated heat shock response |
| REAC:R-HSA-4551638 | 6.36202152662e-12 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | SUMOylation of chromatin organization proteins |
| REAC:R-HSA-70171 | 6.99781939915e-12 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Glycolysis |
| REAC:R-HSA-1169408 | 7.68568545861e-12 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | ISG15 antiviral mechanism |
| GO:1900542 | 8.34001054984e-12 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of purine nucleotide metabolic process |
| REAC:R-HSA-159236 | 8.42897445322e-12 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| GO:0006140 | 9.85356801999e-12 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of nucleotide metabolic process |
| REAC:R-HSA-3108214 | 1.10273472623e-11 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | SUMOylation of DNA damage response and repair proteins |
| GO:1903578 | 1.35976888168e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of ATP metabolic process |
| REAC:R-HSA-1169410 | 1.42611706808e-11 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Antiviral mechanism by IFN-stimulated genes |
| GO:0006096 | 1.47044774414e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | glycolytic process |
| GO:0006757 | 1.5887596316e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | ATP generation from ADP |
| REAC:R-HSA-72202 | 1.82490376468e-11 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Transport of Mature Transcript to Cytoplasm |
| GO:0046031 | 1.85003675181e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | ADP metabolic process |
| GO:0009135 | 2.1473076145e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | purine nucleoside diphosphate metabolic process |
| GO:0009179 | 2.1473076145e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | purine ribonucleoside diphosphate metabolic process |
| REAC:R-HSA-5619102 | 2.31253996467e-11 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | SLC transporter disorders |
| GO:0009185 | 2.48461259742e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | ribonucleoside diphosphate metabolic process |
| GO:0006165 | 2.66963693978e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nucleoside diphosphate phosphorylation |
| REAC:R-HSA-70326 | 2.69440600988e-11 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Glucose metabolism |
| GO:0000776 | 2.86634703008e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | kinetochore |
| GO:0046939 | 2.86634703008e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nucleotide phosphorylation |
| GO:0034605 | 3.07535150102e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | cellular response to heat |
| REAC:R-HSA-3371556 | 3.36474050891e-11 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Cellular response to heat stress |
| GO:0060964 | 3.53280437526e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of gene silencing by miRNA |
| GO:0009132 | 4.04738052769e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nucleoside diphosphate metabolic process |
| GO:0071427 | 4.04738052769e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | mRNA-containing ribonucleoprotein complex export from nucleus |
| GO:0060147 | 4.04738052769e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of posttranscriptional gene silencing |
| GO:0060966 | 4.04738052769e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of gene silencing by RNA |
| GO:0006406 | 4.04738052769e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | mRNA export from nucleus |
| REAC:R-HSA-141424 | 5.48370665902e-11 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Amplification of signal from the kinetochores |
| REAC:R-HSA-141444 | 5.48370665902e-11 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
| GO:0051028 | 5.62310987093e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | mRNA transport |
| GO:0009408 | 7.69784166508e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | response to heat |
| GO:0043467 | 8.69474683567e-11 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of generation of precursor metabolites and energy |
| REAC:R-HSA-5578749 | 1.03493661579e-10 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Transcriptional regulation by small RNAs |
| REAC:R-HSA-72306 | 1.03493661579e-10 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | tRNA processing |
| GO:0071426 | 1.03968613668e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | ribonucleoprotein complex export from nucleus |
| GO:0071166 | 1.10242581734e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | ribonucleoprotein complex localization |
| GO:0006090 | 1.23769376856e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | pyruvate metabolic process |
| REAC:R-HSA-69618 | 1.3886191479e-10 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Mitotic Spindle Checkpoint |
| GO:0006405 | 1.7322141956e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | RNA export from nucleus |
| GO:0006109 | 2.14867872469e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of carbohydrate metabolic process |
| GO:0000775 | 2.38724997009e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | chromosome, centromeric region |
| GO:0035195 | 2.64817423816e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | gene silencing by miRNA |
| GO:0009266 | 2.78755182964e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | response to temperature stimulus |
| REAC:R-HSA-2500257 | 2.80451849089e-10 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Resolution of Sister Chromatid Cohesion |
| REAC:R-HSA-162909 | 3.10311120023e-10 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Host Interactions of HIV factors |
| GO:0060968 | 3.24406068954e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of gene silencing |
| GO:0035194 | 4.14753221949e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | posttranscriptional gene silencing by RNA |
| GO:0016441 | 4.35198803313e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | posttranscriptional gene silencing |
| GO:0050657 | 4.56502241237e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nucleic acid transport |
| GO:0050658 | 4.56502241237e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | RNA transport |
| REAC:R-HSA-168273 | 4.57595719183e-10 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Influenza Viral RNA Transcription and Replication |
| REAC:R-HSA-211000 | 5.02338254484e-10 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Gene Silencing by RNA |
| REAC:R-HSA-68875 | 5.02338254484e-10 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Mitotic Prophase |
| GO:0051236 | 5.25861686629e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | establishment of RNA localization |
| REAC:R-HSA-5663220 | 5.26040261796e-10 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | RHO GTPases Activate Formins |
| REAC:R-HSA-162599 | 5.26040261796e-10 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Late Phase of HIV Life Cycle |
| GO:0016052 | 5.50902719325e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | carbohydrate catabolic process |
| REAC:R-HSA-168255 | 6.58994664246e-10 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Influenza Life Cycle |
| GO:0006611 | 6.61563843774e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | protein export from nucleus |
| GO:0031047 | 6.92030599738e-10 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | gene silencing by RNA |
| REAC:R-HSA-162587 | 9.29347995061e-10 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | HIV Life Cycle |
| REAC:R-HSA-168254 | 1.00971670907e-09 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Influenza Infection |
| GO:0051168 | 1.11506515729e-09 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nuclear export |
| GO:0019083 | 1.16265940181e-09 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | viral transcription |
| GO:0015931 | 1.26309211976e-09 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nucleobase-containing compound transport |
| REAC:R-HSA-5619115 | 1.39151651499e-09 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Disorders of transmembrane transporters |
| REAC:R-HSA-3108232 | 2.03100723442e-09 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | SUMO E3 ligases SUMOylate target proteins |
| GO:0006403 | 2.11582156702e-09 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | RNA localization |
| GO:0019080 | 2.28311304513e-09 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | viral gene expression |
| REAC:R-HSA-2990846 | 2.52047032694e-09 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | SUMOylation |
| REAC:R-HSA-913531 | 2.703962691e-09 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Interferon Signaling |
| GO:0016925 | 2.76012895692e-09 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEH1L | protein sumoylation |
| REAC:R-HSA-2467813 | 3.67336820205e-09 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Separation of Sister Chromatids |
| REAC:R-HSA-68882 | 4.7629597245e-09 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Mitotic Anaphase |
| REAC:R-HSA-68877 | 4.7629597245e-09 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Mitotic Prometaphase |
| REAC:R-HSA-2555396 | 4.91631747693e-09 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Mitotic Metaphase and Anaphase |
| GO:0031503 | 9.27135075192e-09 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | protein-containing complex localization |
| GO:0016458 | 9.27135075192e-09 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | gene silencing |
| GO:0019058 | 1.14784284344e-08 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | viral life cycle |
| GO:0046034 | 1.18277719085e-08 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | ATP metabolic process |
| REAC:R-HSA-162906 | 1.21809078273e-08 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | HIV Infection |
| REAC:R-HSA-72203 | 1.67289912286e-08 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Processing of Capped Intron-Containing Pre-mRNA |
| GO:0006913 | 2.82577461251e-08 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nucleocytoplasmic transport |
| GO:0051169 | 3.05746776784e-08 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nuclear transport |
| GO:0098687 | 3.22081609546e-08 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | chromosomal region |
| REAC:R-HSA-71387 | 3.22912902309e-08 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Metabolism of carbohydrates |
| GO:0040029 | 5.31149371955e-08 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of gene expression, epigenetic |
| GO:0009150 | 5.31149371955e-08 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | purine ribonucleotide metabolic process |
| REAC:R-HSA-69620 | 5.59924446252e-08 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Cell Cycle Checkpoints |
| GO:0062012 | 6.42611310786e-08 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of small molecule metabolic process |
| GO:0009259 | 6.57859714771e-08 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | ribonucleotide metabolic process |
| GO:0019693 | 7.91420145587e-08 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | ribose phosphate metabolic process |
| GO:0005635 | 8.66488583061e-08 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nuclear envelope |
| REAC:R-HSA-195258 | 8.74310498089e-08 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | RHO GTPase Effectors |
| GO:0006163 | 1.05801897442e-07 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | purine nucleotide metabolic process |
| GO:0072521 | 1.68513129606e-07 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | purine-containing compound metabolic process |
| REAC:R-HSA-5663205 | 2.12266820846e-07 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Infectious disease |
| REAC:R-HSA-68886 | 2.89783215116e-07 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | M Phase |
| GO:0006091 | 3.03570543251e-07 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | generation of precursor metabolites and energy |
| GO:0005975 | 3.45887706383e-07 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | carbohydrate metabolic process |
| GO:0009117 | 3.93163607046e-07 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nucleotide metabolic process |
| GO:0006753 | 4.3022982802e-07 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nucleoside phosphate metabolic process |
| REAC:R-HSA-2262752 | 4.59314510627e-07 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Cellular responses to stress |
| REAC:R-HSA-194315 | 6.39188695657e-07 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Signaling by Rho GTPases |
| GO:0016032 | 8.64682429086e-07 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | viral process |
| GO:0055086 | 1.34208206789e-06 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nucleobase-containing small molecule metabolic process |
| REAC:R-HSA-8953897 | 1.36666920225e-06 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Cellular responses to external stimuli |
| GO:0032787 | 1.68008519728e-06 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | monocarboxylic acid metabolic process |
| GO:0044403 | 1.70500171504e-06 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | symbiotic process |
| REAC:R-HSA-69278 | 1.91008072332e-06 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Cell Cycle, Mitotic |
| GO:0010608 | 2.02962689283e-06 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | posttranscriptional regulation of gene expression |
| GO:0044419 | 2.50873535442e-06 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | interspecies interaction between organisms |
| GO:0080135 | 5.45303072513e-06 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of cellular response to stress |
| REAC:R-HSA-1640170 | 5.63049101506e-06 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Cell Cycle |
| REAC:R-HSA-8953854 | 7.75839378739e-06 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Metabolism of RNA |
| REAC:R-HSA-1280215 | 1.08879498241e-05 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Cytokine Signaling in Immune system |
| GO:0018205 | 1.63926986258e-05 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEH1L | peptidyl-lysine modification |
| GO:0009628 | 2.1793351769e-05 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | response to abiotic stimulus |
| GO:0019637 | 5.31312605982e-05 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | organophosphate metabolic process |
| GO:0009894 | 5.36111558553e-05 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of catabolic process |
| CORUM:1347 | 6.04024714829e-05 | 0.285714285714 | NUP160 NUP107 | NPC subcomplex (NUP98, NUP107, NUP133, NUP160) |
| REAC:R-HSA-1643685 | 7.29866025129e-05 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Disease |
| GO:0019752 | 7.35524415851e-05 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | carboxylic acid metabolic process |
| GO:0031967 | 7.6116924814e-05 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | organelle envelope |
| GO:0031975 | 7.6116924814e-05 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | envelope |
| GO:1901135 | 9.87249792027e-05 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | carbohydrate derivative metabolic process |
| CORUM:6216 | 0.000100648251269 | 0.285714285714 | SEC13 SEH1L | GATOR2 complex |
| GO:0043436 | 0.000131987041465 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | oxoacid metabolic process |
| GO:0006082 | 0.00014615487486 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | organic acid metabolic process |
| HP:0000097 | 0.000156527655735 | 0.428571428571 | NUP85 NUP107 NUP160 | Focal segmental glomerulosclerosis |
| GO:0006886 | 0.000166634167312 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | intracellular protein transport |
| CORUM:6217 | 0.000281625889725 | 0.285714285714 | SEC13 SEH1L | GATOR complex |
| CORUM:6753 | 0.000281625889725 | 0.285714285714 | SEC13 SEH1L | SOG complex |
| REAC:R-HSA-597592 | 0.00039194203242 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Post-translational protein modification |
| REAC:R-HSA-74160 | 0.000444522787502 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Gene expression (Transcription) |
| GO:0042325 | 0.000524382122071 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of phosphorylation |
| GO:0080134 | 0.000545137412981 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of response to stress |
| HP:0000096 | 0.000799483936187 | 0.428571428571 | NUP85 NUP107 NUP160 | Glomerulosclerosis |
| GO:0019220 | 0.00107799561265 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of phosphate metabolic process |
| GO:0051174 | 0.00108432081742 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | regulation of phosphorus metabolic process |
| HP:0012588 | 0.0011537726365 | 0.285714285714 | NUP85 NUP160 | Steroid-resistant nephrotic syndrome |
| GO:0044427 | 0.00123884712147 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | chromosomal part |
| GO:0005694 | 0.0015963674554 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | chromosome |
| CORUM:0000000 | 0.00178557880024 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | CORUM root |
| GO:0032446 | 0.00211480680865 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEH1L | protein modification by small protein conjugation |
| GO:0015031 | 0.00215038892806 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | protein transport |
| GO:0015833 | 0.00237664126968 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | peptide transport |
| GO:0042886 | 0.00259607662238 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | amide transport |
| REAC:R-HSA-168256 | 0.00280594353387 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Immune System |
| HP:0012622 | 0.00313574842301 | 0.428571428571 | NUP85 NUP107 NUP160 | Chronic kidney disease |
| REAC:R-HSA-392499 | 0.00334345902737 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Metabolism of proteins |
| GO:0010629 | 0.00342917010303 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | negative regulation of gene expression |
| GO:0046907 | 0.00363859974134 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | intracellular transport |
| GO:0045184 | 0.0036745489957 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | establishment of protein localization |
| REAC:R-HSA-1430728 | 0.00415508232387 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Metabolism |
| GO:0044281 | 0.00456795183371 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | small molecule metabolic process |
| GO:0017056 | 0.00487641079113 | 0.428571428571 | NUP85 NUP107 NUP160 | structural constituent of nuclear pore |
| GO:0051704 | 0.00488132284224 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | multi-organism process |
| REAC:R-HSA-162582 | 0.00544066626924 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEC13 | Signal Transduction |
| GO:0034613 | 0.00546147189892 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | cellular protein localization |
| GO:0070727 | 0.00569376331345 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | cellular macromolecule localization |
| GO:0071705 | 0.00632623715462 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | nitrogen compound transport |
| GO:0033554 | 0.00695537920525 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | cellular response to stress |
| HP:0000100 | 0.00774789772593 | 0.428571428571 | NUP85 NUP107 NUP160 | Nephrotic syndrome |
| GO:0070647 | 0.00861186668593 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEH1L | protein modification by small protein conjugation or removal |
| GO:0016310 | 0.0100383435656 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | phosphorylation |
| GO:1901575 | 0.0115839240794 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | organic substance catabolic process |
| HP:0000095 | 0.0120174670694 | 0.428571428571 | NUP85 NUP107 NUP160 | Abnormality of renal glomerulus morphology |
| HP:0031263 | 0.0120174670694 | 0.428571428571 | NUP85 NUP107 NUP160 | Abnormal renal corpuscle morphology |
| GO:0018193 | 0.0134503806881 | 0.857142857143 | NUP160 NUP85 NUP43 NUP107 NUP37 SEH1L | peptidyl-amino acid modification |
| HP:0000093 | 0.0154734133885 | 0.428571428571 | NUP85 NUP107 NUP160 | Proteinuria |
| GO:0051649 | 0.015479871164 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | establishment of localization in cell |
| GO:0071702 | 0.0180623174395 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | organic substance transport |
| HP:0020129 | 0.0183608015714 | 0.428571428571 | NUP85 NUP107 NUP160 | Abnormal urine protein level |
| HP:0011035 | 0.0195289520329 | 0.428571428571 | NUP85 NUP107 NUP160 | Abnormal renal cortex morphology |
| HP:0012575 | 0.029622117541 | 0.428571428571 | NUP85 NUP107 NUP160 | Abnormal nephron morphology |
| GO:0010605 | 0.0300563900312 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | negative regulation of macromolecule metabolic process |
| GO:0008104 | 0.0342210950981 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | protein localization |
| GO:0009056 | 0.0452806546755 | 1.0 | NUP160 NUP85 NUP43 NUP107 SEC13 SEH1L NUP37 | catabolic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NUP107 | NUP85 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM hein (NUP107) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| NUP43 | NUP107 | 1.0 | 0.949 | hein_WMM bioplex (NUP43) bioplex_WMM youn_WMM hein (NUP107) gupta_WMM |
| NUP160 | NUP85 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| NUP107 | NUP37 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru hein (NUP107) Malo fraction |
| NUP43 | NUP85 | 1.0 | 0.949 | hein_WMM bioplex (NUP43) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| NUP43 | NUP160 | 0.999 | 0.949 | hein_WMM bioplex (NUP43) bioplex_WMM gupta_WMM boldt_WMM |
| NUP43 | SEH1L | 0.999 | 0.949 | hein_WMM bioplex (NUP43) bioplex_WMM hein (SEH1L) |
| NUP43 | NUP37 | 0.995 | 0.924 | hein_WMM bioplex (NUP43) bioplex_WMM |
| SEC13 | NUP107 | 0.995 | 0.923 | hein_WMM bioplex (SEC13) bioplex_WMM boldt youn_WMM hein (NUP107) gupta_WMM boldt_WMM |
| NUP107 | NUP160 | 0.971 | 0.884 | hein_WMM bioplex_WMM boldt youn_WMM hein (NUP107) gupta_WMM boldt_WMM treiber_WMM |
| SEC13 | NUP37 | 0.831 | 0.778 | hein_WMM bioplex (SEC13) bioplex_WMM Guru fraction |
| SEC13 | NUP160 | 0.587 | 0.662 | hein_WMM bioplex (SEC13) bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| SEC13 | SEH1L | 0.517 | 0.631 | hein_WMM bioplex (SEC13) bioplex_WMM youn_WMM hein (SEH1L) boldt_WMM |
| SEC13 | NUP85 | 0.288 | 0.489 | hein_WMM bioplex (SEC13) bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| NUP43 | SEC13 | 0.103 | 0.366 | hein_WMM bioplex (NUP43,SEC13) bioplex_WMM gupta_WMM treiber_WMM |
| SEH1L | NUP85 | 0.1 | 0.361 | hein_WMM bioplex_WMM youn_WMM hein (SEH1L) |
| SEH1L | NUP160 | 0.099 | 0.358 | hein_WMM bioplex_WMM youn_WMM hein (SEH1L) gupta_WMM |
| NUP107 | SEH1L | 0.083 | 0.35 | hein_WMM bioplex_WMM youn_WMM hein (NUP107,SEH1L) |
| NUP160 | NUP37 | 0.053 | 0.301 | hein_WMM bioplex_WMM WMM_only |
| NUP85 | NUP37 | 0.044 | 0.275 | hein_WMM bioplex_WMM WMM_only |
| SEH1L | NUP37 | 0.04 | 0.269 | hein_WMM bioplex_WMM hein (SEH1L) |
Images
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Complex HuMAP2_05315 has an average edge precision of 0.677 which is ranked 1476 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SEC13 | HuMAP2_00541 HuMAP2_01606 HuMAP2_03792 HuMAP2_05315 HuMAP2_06753 |
| SEH1L | HuMAP2_00541 HuMAP2_05315 HuMAP2_06753 |
| NUP85 | HuMAP2_00541 HuMAP2_05315 |
| NUP160 | HuMAP2_00541 HuMAP2_05315 |
| NUP43 | HuMAP2_00541 HuMAP2_03411 HuMAP2_04705 HuMAP2_04997 HuMAP2_05315 |
| NUP107 | HuMAP2_00541 HuMAP2_01007 HuMAP2_03792 HuMAP2_05315 HuMAP2_05974 |
| NUP37 | HuMAP2_00541 HuMAP2_03792 HuMAP2_04294 HuMAP2_05315 |