hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05328
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FLNA | Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) | UniProt NCBI |
| SORBS2 | Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin) | UniProt NCBI |
| FLNC | Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin) | UniProt NCBI |
| PPP1R9B | Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) | UniProt NCBI |
| HSPB7 | Heat shock protein beta-7 (HspB7) (Cardiovascular heat shock protein) (cvHsp) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0006389 | 0.000278784943944 | 0.4 | FLNA FLNC | Limited knee flexion |
| REAC:R-HSA-446353 | 0.00206071490935 | 0.4 | FLNA FLNC | Cell-extracellular matrix interactions |
| KEGG:05132 | 0.00941045001151 | 0.4 | FLNA FLNC | Salmonella infection |
| WP:WP4217 | 0.0226950547009 | 0.4 | FLNA FLNC | Ebola Virus Pathway on Host |
| REAC:R-HSA-446728 | 0.0332320424718 | 0.4 | FLNA FLNC | Cell junction organization |
| CORUM:6720 | 0.0499494897235 | 0.2 | FLNA | FILIP1-FLNA complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HSPB7 | FLNA | 0.076 | 0.357 | bioplex (HSPB7) bioplex_WMM |
| HSPB7 | FLNC | 0.068 | 0.35 | bioplex (HSPB7) bioplex_WMM |
| FLNA | SORBS2 | 0.047 | 0.291 | hein_WMM hein (FLNA) |
| FLNA | PPP1R9B | 0.044 | 0.28 | hein_WMM bioplex_WMM hein (FLNA) |
| FLNC | FLNA | 0.007 | 0.004 | bioplex_WMM WMM_only treiber_WMM |
| SORBS2 | PPP1R9B | 0.006 | 0.003 | hein_WMM WMM_only |
| FLNC | PPP1R9B | 0.006 | 0.006 | bioplex_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_05328 has an average edge precision of 0.184 which is ranked 6387 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FLNA | HuMAP2_02813 HuMAP2_03895 HuMAP2_05328 HuMAP2_05368 |
| SORBS2 | HuMAP2_04553 HuMAP2_05328 HuMAP2_05368 |
| FLNC | HuMAP2_01648 HuMAP2_02737 HuMAP2_05328 |
| PPP1R9B | HuMAP2_04615 HuMAP2_05328 HuMAP2_05394 HuMAP2_06738 |
| HSPB7 | HuMAP2_01648 HuMAP2_02737 HuMAP2_05328 |