hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05335
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PHKA1 | Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit) | UniProt NCBI |
| PHKG1 | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (PHK-gamma-M) (EC 2.7.11.19) (Phosphorylase kinase subunit gamma-1) (Serine/threonine-protein kinase PHKG1) (EC 2.7.11.1) (EC 2.7.11.26) | UniProt NCBI |
| PHKG2 | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (PHK-gamma-LT) (PHK-gamma-T) (EC 2.7.11.19) (PSK-C3) (Phosphorylase kinase subunit gamma-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-70221 | 1.63653275606e-07 | 1.0 | PHKG2 PHKA1 PHKG1 | Glycogen breakdown (glycogenolysis) |
| WP:WP500 | 5.43365608036e-07 | 1.0 | PHKG2 PHKA1 PHKG1 | Glycogen Synthesis and Degradation |
| REAC:R-HSA-8982491 | 1.16895196861e-06 | 1.0 | PHKG2 PHKA1 PHKG1 | Glycogen metabolism |
| KEGG:04922 | 4.29674110668e-06 | 1.0 | PHKG2 PHKA1 PHKG1 | Glucagon signaling pathway |
| KEGG:04910 | 9.55549752694e-06 | 1.0 | PHKG2 PHKA1 PHKG1 | Insulin signaling pathway |
| CORUM:6640 | 1.00675659188e-05 | 0.666666666667 | PHKA1 PHKG1 | Phosphorylase kinase complex |
| KEGG:04020 | 1.97683471245e-05 | 1.0 | PHKG2 PHKA1 PHKG1 | Calcium signaling pathway |
| GO:0005980 | 5.08584025729e-05 | 1.0 | PHKG2 PHKA1 PHKG1 | glycogen catabolic process |
| GO:0044247 | 6.17566316957e-05 | 1.0 | PHKG2 PHKA1 PHKG1 | cellular polysaccharide catabolic process |
| GO:0000272 | 6.17566316957e-05 | 1.0 | PHKG2 PHKA1 PHKG1 | polysaccharide catabolic process |
| GO:0009251 | 6.17566316957e-05 | 1.0 | PHKG2 PHKA1 PHKG1 | glucan catabolic process |
| GO:0044275 | 0.000408229499224 | 1.0 | PHKG2 PHKA1 PHKG1 | cellular carbohydrate catabolic process |
| REAC:R-HSA-71387 | 0.00133225455863 | 1.0 | PHKG2 PHKA1 PHKG1 | Metabolism of carbohydrates |
| GO:0005977 | 0.0015707980909 | 1.0 | PHKG2 PHKA1 PHKG1 | glycogen metabolic process |
| GO:0044042 | 0.00167324144465 | 1.0 | PHKG2 PHKA1 PHKG1 | glucan metabolic process |
| GO:0006073 | 0.00167324144465 | 1.0 | PHKG2 PHKA1 PHKG1 | cellular glucan metabolic process |
| GO:0006112 | 0.00225266395968 | 1.0 | PHKG2 PHKA1 PHKG1 | energy reserve metabolic process |
| GO:0044264 | 0.00378386515143 | 1.0 | PHKG2 PHKA1 PHKG1 | cellular polysaccharide metabolic process |
| GO:0005976 | 0.00497140885151 | 1.0 | PHKG2 PHKA1 PHKG1 | polysaccharide metabolic process |
| GO:0005964 | 0.00811409485621 | 0.666666666667 | PHKG2 PHKA1 | phosphorylase kinase complex |
| GO:0004689 | 0.00811409485621 | 0.666666666667 | PHKG2 PHKA1 | phosphorylase kinase activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PHKG2 | PHKA1 | 1.0 | 0.949 | hein_WMM bioplex (PHKG2) bioplex_WMM hein (PHKG2) boldt_WMM |
| PHKG2 | PHKG1 | 0.991 | 0.909 | bioplex (PHKG2) |
| PHKA1 | PHKG1 | 0.008 | 0.085 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05335 has an average edge precision of 0.648 which is ranked 1660 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PHKA1 | HuMAP2_00680 HuMAP2_05335 HuMAP2_06680 |
| PHKG1 | HuMAP2_00680 HuMAP2_05335 HuMAP2_06680 |
| PHKG2 | HuMAP2_00680 HuMAP2_05335 HuMAP2_06680 |