hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05337
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HAUS6 | HAUS augmin-like complex subunit 6 | UniProt NCBI |
| HAUS7 | HAUS augmin-like complex subunit 7 (26S proteasome-associated UCH37-interacting protein 1) (UCHL5-interacting protein) (X-linked protein STS1769) | UniProt NCBI |
| HAUS1 | HAUS augmin-like complex subunit 1 (Coiled-coil domain-containing protein 5) (Enhancer of invasion-cluster) (HEI-C) | UniProt NCBI |
| HAUS2 | HAUS augmin-like complex subunit 2 (Centrosomal protein of 27 kDa) (Cep27) | UniProt NCBI |
| HAUS4 | HAUS augmin-like complex subunit 4 | UniProt NCBI |
| ALG11 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase) | UniProt NCBI |
| HAUS3 | HAUS augmin-like complex subunit 3 | UniProt NCBI |
| HAUS5 | HAUS augmin-like complex subunit 5 | UniProt NCBI |
| HAUS8 | HAUS augmin-like complex subunit 8 (HEC1/NDC80-interacting centrosome-associated protein 1) (Sarcoma antigen NY-SAR-48) | UniProt NCBI |
| GP1BB | Platelet glycoprotein Ib beta chain (GP-Ib beta) (GPIb-beta) (GPIbB) (Antigen CD42b-beta) (CD antigen CD42c) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070652 | 3.75343444527e-23 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | HAUS complex |
| CORUM:6435 | 2.7716953664e-22 | 0.7 | HAUS7 HAUS6 HAUS8 HAUS3 HAUS5 HAUS2 HAUS1 | HAUS augmin-like complex |
| REAC:R-HSA-380259 | 1.01711550497e-15 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Loss of Nlp from mitotic centrosomes |
| REAC:R-HSA-380284 | 1.01711550497e-15 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Loss of proteins required for interphase microtubule organization from the centrosome |
| REAC:R-HSA-8854518 | 1.47162576634e-15 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | AURKA Activation by TPX2 |
| REAC:R-HSA-380287 | 4.06250983755e-15 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Centrosome maturation |
| REAC:R-HSA-380270 | 4.06250983755e-15 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Recruitment of mitotic centrosome proteins and complexes |
| REAC:R-HSA-2565942 | 6.78450650339e-15 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Regulation of PLK1 Activity at G2/M Transition |
| REAC:R-HSA-380320 | 1.20546926214e-14 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Recruitment of NuMA to mitotic centrosomes |
| REAC:R-HSA-5620912 | 1.88914425957e-14 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Anchoring of the basal body to the plasma membrane |
| GO:0051225 | 2.88107153651e-12 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | spindle assembly |
| GO:0097711 | 4.13533602532e-12 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | ciliary basal body-plasma membrane docking |
| REAC:R-HSA-69275 | 5.57426898501e-12 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | G2/M Transition |
| REAC:R-HSA-5617833 | 5.81725052283e-12 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Cilium Assembly |
| REAC:R-HSA-68877 | 5.81725052283e-12 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Mitotic Prometaphase |
| REAC:R-HSA-453274 | 6.06944161412e-12 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Mitotic G2-G2/M phases |
| GO:0007098 | 1.30557251176e-11 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | centrosome cycle |
| GO:0031023 | 2.52635955475e-11 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | microtubule organizing center organization |
| GO:0005875 | 7.70365817864e-11 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | microtubule associated complex |
| REAC:R-HSA-1852241 | 1.25081597484e-10 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Organelle biogenesis and maintenance |
| GO:0007051 | 1.38923061881e-10 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | spindle organization |
| GO:0140056 | 1.47017655655e-10 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | organelle localization by membrane tethering |
| GO:0022406 | 2.40542660392e-10 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | membrane docking |
| GO:0010389 | 7.14755236364e-10 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | regulation of G2/M transition of mitotic cell cycle |
| REAC:R-HSA-68886 | 1.41065056712e-09 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | M Phase |
| GO:1902749 | 1.45059654578e-09 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | regulation of cell cycle G2/M phase transition |
| GO:0000086 | 5.06657050336e-09 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | G2/M transition of mitotic cell cycle |
| GO:0044839 | 9.47182111582e-09 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | cell cycle G2/M phase transition |
| REAC:R-HSA-69278 | 1.74291118486e-08 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Cell Cycle, Mitotic |
| REAC:R-HSA-1640170 | 7.35257041889e-08 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | Cell Cycle |
| GO:0060271 | 9.0255477161e-08 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | cilium assembly |
| GO:0044782 | 1.36886579654e-07 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | cilium organization |
| GO:1901990 | 1.77227498434e-07 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | regulation of mitotic cell cycle phase transition |
| GO:1901987 | 3.09470086864e-07 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | regulation of cell cycle phase transition |
| GO:0120031 | 1.32111669743e-06 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | plasma membrane bounded cell projection assembly |
| GO:0005813 | 1.49616393749e-06 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | centrosome |
| GO:0030031 | 1.5497560558e-06 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | cell projection assembly |
| GO:0000226 | 1.63328686991e-06 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | microtubule cytoskeleton organization |
| GO:0044772 | 1.94080439628e-06 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | mitotic cell cycle phase transition |
| GO:0051640 | 2.7106570718e-06 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | organelle localization |
| GO:0044770 | 3.2383891302e-06 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | cell cycle phase transition |
| GO:0007346 | 4.16555773181e-06 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | regulation of mitotic cell cycle |
| GO:0005815 | 1.35191877288e-05 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | microtubule organizing center |
| GO:0010564 | 1.48335514647e-05 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | regulation of cell cycle process |
| GO:0007017 | 1.94691475822e-05 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | microtubule-based process |
| GO:0070925 | 3.63234245382e-05 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | organelle assembly |
| GO:1903047 | 5.54626397565e-05 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | mitotic cell cycle process |
| GO:0000278 | 0.000186820011075 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | mitotic cell cycle |
| GO:0051726 | 0.000348155094002 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | regulation of cell cycle |
| GO:0015630 | 0.000462975384572 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | microtubule cytoskeleton |
| GO:0120036 | 0.000866643202871 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | plasma membrane bounded cell projection organization |
| GO:0030030 | 0.00094405889341 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | cell projection organization |
| GO:0007010 | 0.00101959286507 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | cytoskeleton organization |
| GO:0022402 | 0.00163992316578 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | cell cycle process |
| GO:0044430 | 0.0031377807376 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | cytoskeletal part |
| GO:0007049 | 0.00632967942447 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | cell cycle |
| GO:0005856 | 0.0169472823808 | 0.8 | HAUS7 HAUS6 HAUS8 HAUS1 HAUS5 HAUS4 HAUS2 HAUS3 | cytoskeleton |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HAUS7 | HAUS1 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS7 | HAUS2 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS7 | HAUS4 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS7 | HAUS3 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM gupta_WMM |
| HAUS7 | HAUS8 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM gupta_WMM |
| HAUS7 | HAUS5 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM gupta_WMM |
| HAUS7 | HAUS6 | 1.0 | 0.949 | hein_WMM bioplex (HAUS7) bioplex_WMM youn_WMM gupta_WMM |
| HAUS1 | HAUS4 | 0.997 | 0.934 | hein_WMM bioplex_WMM boldt youn_WMM hein (HAUS1,HAUS4) gupta_WMM boldt_WMM |
| HAUS2 | HAUS3 | 0.985 | 0.899 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS2 | HAUS8 | 0.978 | 0.894 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS4 | HAUS2 | 0.963 | 0.871 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2,HAUS4) gupta_WMM |
| HAUS2 | HAUS5 | 0.944 | 0.856 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS1 | HAUS2 | 0.905 | 0.828 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1,HAUS2) gupta_WMM |
| HAUS4 | HAUS3 | 0.851 | 0.791 | hein_WMM bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS4 | HAUS5 | 0.797 | 0.763 | hein_WMM bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS1 | HAUS3 | 0.756 | 0.747 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS4 | HAUS8 | 0.681 | 0.708 | hein_WMM bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS2 | HAUS6 | 0.632 | 0.681 | hein_WMM bioplex_WMM youn_WMM hein (HAUS2) gupta_WMM |
| HAUS6 | HAUS8 | 0.383 | 0.55 | hein_WMM bioplex (HAUS8) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| HAUS4 | HAUS6 | 0.33 | 0.52 | hein_WMM bioplex_WMM youn_WMM hein (HAUS4) gupta_WMM |
| HAUS1 | HAUS5 | 0.312 | 0.505 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS1 | HAUS6 | 0.161 | 0.418 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS1 | HAUS8 | 0.155 | 0.416 | hein_WMM bioplex_WMM youn_WMM hein (HAUS1) gupta_WMM |
| HAUS7 | GP1BB | 0.047 | 0.292 | bioplex (HAUS7) bioplex_WMM |
| HAUS7 | ALG11 | 0.035 | 0.262 | bioplex (HAUS7) bioplex_WMM |
| HAUS3 | HAUS8 | 0.022 | 0.205 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS5 | HAUS8 | 0.021 | 0.187 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS3 | HAUS5 | 0.018 | 0.178 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS6 | HAUS3 | 0.016 | 0.157 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS6 | HAUS5 | 0.016 | 0.154 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HAUS2 | GP1BB | 0.008 | 0.031 | bioplex_WMM WMM_only |
| HAUS2 | ALG11 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| GP1BB | HAUS3 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| ALG11 | HAUS3 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| GP1BB | HAUS8 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| HAUS1 | GP1BB | 0.007 | 0.004 | bioplex_WMM WMM_only |
| HAUS4 | GP1BB | 0.007 | 0.003 | bioplex_WMM WMM_only |
| ALG11 | HAUS8 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| HAUS1 | ALG11 | 0.006 | 0.007 | bioplex_WMM WMM_only |
| GP1BB | HAUS5 | 0.006 | 0.002 | bioplex_WMM WMM_only |
| GP1BB | HAUS6 | 0.006 | 0.003 | bioplex_WMM WMM_only |
| HAUS4 | ALG11 | 0.006 | 0.004 | bioplex_WMM WMM_only |
| ALG11 | HAUS5 | 0.006 | 0.003 | bioplex_WMM WMM_only |
| ALG11 | HAUS6 | 0.006 | 0.007 | bioplex_WMM WMM_only |
| ALG11 | GP1BB | 0.004 | 0.012 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05337 has an average edge precision of 0.435 which is ranked 2978 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HAUS6 | HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS7 | HuMAP2_00474 HuMAP2_03612 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS1 | HuMAP2_00474 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS2 | HuMAP2_00474 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS4 | HuMAP2_00474 HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| ALG11 | HuMAP2_03612 HuMAP2_05337 |
| HAUS3 | HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS5 | HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| HAUS8 | HuMAP2_04538 HuMAP2_05337 HuMAP2_06334 |
| GP1BB | HuMAP2_03612 HuMAP2_05337 HuMAP2_06334 |