hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05341
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PDIA3 | Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60) | UniProt NCBI |
| SEC24C | Protein transport protein Sec24C (SEC24-related protein C) | UniProt NCBI |
| IVD | Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) (EC 1.3.8.4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-983170 | 0.00200655101382 | 0.666666666667 | PDIA3 SEC24C | Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| KEGG:04141 | 0.00544616782939 | 0.666666666667 | PDIA3 SEC24C | Protein processing in endoplasmic reticulum |
| MIRNA:hsa-miR-6728-5p | 0.0271734899676 | 0.666666666667 | IVD SEC24C | hsa-miR-6728-5p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PDIA3 | IVD | 0.84 | 0.784 | bioplex (IVD) fraction |
| SEC24C | IVD | 0.659 | 0.696 | bioplex_WMM fraction |
| PDIA3 | SEC24C | 0.0 | 0.006 | bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_05341 has an average edge precision of 0.495 which is ranked 2525 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PDIA3 | HuMAP2_00278 HuMAP2_01152 HuMAP2_04961 HuMAP2_05341 |
| SEC24C | HuMAP2_00758 HuMAP2_01054 HuMAP2_02478 HuMAP2_02576 HuMAP2_05176 HuMAP2_05341 HuMAP2_06134 |
| IVD | HuMAP2_01054 HuMAP2_01152 HuMAP2_03041 HuMAP2_05065 HuMAP2_05176 HuMAP2_05341 |