hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_05342

Confidence: Medium

Genename	Protein Name	Links
GPAT3	Glycerol-3-phosphate acyltransferase 3 (GPAT-3) (EC 2.3.1.15) (1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10) (AGPAT 10) (1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9) (1-AGP acyltransferase 9) (1-AGPAT 9) (EC 2.3.1.51) (Acyl-CoA:glycerol-3-phosphate acyltransferase 3) (hGPAT3) (Lung cancer metastasis-associated protein 1) (Lysophosphatidic acid acyltransferase theta) (LPAAT-theta) (MAG-1)	UniProt NCBI
SLC6A15	Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Sodium-coupled branched-chain amino-acid transporter 1) (Solute carrier family 6 member 15) (Transporter v7-3)	UniProt NCBI
GPAT4	Glycerol-3-phosphate acyltransferase 4 (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase 6) (1-AGP acyltransferase 6) (1-AGPAT 6) (Acyl-CoA:glycerol-3-phosphate acyltransferase 4) (Lysophosphatidic acid acyltransferase zeta) (LPAAT-zeta) (Testis spermatogenesis apoptosis-related protein 7) (TSARG7)	UniProt NCBI
TEX2	Testis-expressed protein 2 (Transmembrane protein 96)	UniProt NCBI
LPCAT1	Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (EC 2.3.1.23) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3)	UniProt NCBI
TRAM1	Translocating chain-associated membrane protein 1	UniProt NCBI
EI24	Etoposide-induced protein 2.4 homolog (p53-induced gene 8 protein)	UniProt NCBI
CHP1	Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22)	UniProt NCBI
TMEM41B	Transmembrane protein 41B	UniProt NCBI
HACD2	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 2) (HACD2) (Protein-tyrosine phosphatase-like member B)	UniProt NCBI
TMEM161A	Transmembrane protein 161A (Adaptive response to oxidative stress protein 29) (AROS-29)	UniProt NCBI
TLCD1	TLC domain-containing protein 1 (Calfacilitin)	UniProt NCBI
UBE2G2	Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2)	UniProt NCBI
AUP1	Ancient ubiquitous protein 1	UniProt NCBI
AGPAT2	1-acyl-sn-glycerol-3-phosphate acyltransferase beta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 2) (1-AGP acyltransferase 2) (1-AGPAT 2) (Lysophosphatidic acid acyltransferase beta) (LPAAT-beta)	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0005783	3.71948016966e-06	0.8	CHP1 AUP1 GPAT4 TRAM1 TEX2 UBE2G2 TMEM41B LPCAT1 GPAT3 AGPAT2 EI24 HACD2	endoplasmic reticulum
REAC:R-HSA-1483166	5.54400157413e-06	0.266666666667	LPCAT1 GPAT3 AGPAT2 GPAT4	Synthesis of PA
KEGG:00564	5.11333582757e-05	0.266666666667	LPCAT1 GPAT3 AGPAT2 GPAT4	Glycerophospholipid metabolism
REAC:R-HSA-1483206	0.000869250258195	0.266666666667	LPCAT1 GPAT3 AGPAT2 GPAT4	Glycerophospholipid biosynthesis
KEGG:00561	0.00112236315094	0.2	GPAT4 AGPAT2 GPAT3	Glycerolipid metabolism
GO:0006654	0.00171190751575	0.266666666667	LPCAT1 GPAT3 AGPAT2 GPAT4	phosphatidic acid biosynthetic process
GO:0046473	0.00192475664625	0.266666666667	LPCAT1 GPAT3 AGPAT2 GPAT4	phosphatidic acid metabolic process
GO:0008374	0.00215678379103	0.266666666667	LPCAT1 GPAT3 AGPAT2 GPAT4	O-acyltransferase activity
GO:0005789	0.00395553104907	0.533333333333	TRAM1 GPAT4 AUP1 TMEM41B LPCAT1 AGPAT2 GPAT3 HACD2	endoplasmic reticulum membrane
GO:0042175	0.00448663482668	0.533333333333	TRAM1 GPAT4 AUP1 TMEM41B LPCAT1 AGPAT2 GPAT3 HACD2	nuclear outer membrane-endoplasmic reticulum membrane network
REAC:R-HSA-1483257	0.00743696206223	0.266666666667	LPCAT1 GPAT3 AGPAT2 GPAT4	Phospholipid metabolism
HPA:007030_22	0.0097145159208	0.533333333333	CHP1 GPAT4 AUP1 TEX2 UBE2G2 GPAT3 HACD2 TRAM1	cerebellum; cells in molecular layer[Approved,Medium]
HPA:032010_22	0.0188778589812	0.666666666667	CHP1 GPAT4 AUP1 TEX2 UBE2G2 TMEM161A GPAT3 EI24 HACD2 TRAM1	pancreas; exocrine glandular cells[Approved,Medium]
GO:0044432	0.0440760498546	0.533333333333	TRAM1 GPAT4 AUP1 TMEM41B LPCAT1 AGPAT2 GPAT3 HACD2	endoplasmic reticulum part

Edges

Protein 1	Protein 2	Score	Precision	Evidence
CHP1	GPAT4	0.742	0.74	bioplex (GPAT4) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
SLC6A15	GPAT3	0.232	0.47	bioplex (SLC6A15) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
GPAT4	GPAT3	0.142	0.406	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
TEX2	SLC6A15	0.063	0.348	bioplex (SLC6A15) bioplex_WMM youn_WMM gupta_WMM
CHP1	AUP1	0.059	0.328	bioplex (AUP1) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
SLC6A15	GPAT4	0.058	0.325	bioplex (GPAT4,SLC6A15) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
AUP1	GPAT4	0.058	0.325	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
HACD2	SLC6A15	0.045	0.282	bioplex (SLC6A15) bioplex_WMM boldt gupta_WMM boldt_WMM
SLC6A15	CHP1	0.044	0.279	bioplex (SLC6A15) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
SLC6A15	TMEM161A	0.041	0.27	bioplex (SLC6A15) bioplex_WMM boldt gupta_WMM boldt_WMM
AUP1	GPAT3	0.033	0.254	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
HACD2	TMEM161A	0.029	0.23	bioplex_WMM boldt gupta_WMM boldt_WMM
TRAM1	TMEM161A	0.027	0.225	hein_WMM bioplex_WMM boldt boldt_WMM
SLC6A15	TLCD1	0.027	0.223	bioplex (SLC6A15) bioplex_WMM
SLC6A15	AGPAT2	0.026	0.218	bioplex (SLC6A15) bioplex_WMM boldt boldt_WMM
AUP1	TMEM161A	0.025	0.217	bioplex_WMM boldt gupta_WMM boldt_WMM
HACD2	TMEM41B	0.023	0.207	bioplex_WMM boldt gupta_WMM boldt_WMM
CHP1	GPAT3	0.023	0.211	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
UBE2G2	AUP1	0.022	0.21	bioplex (AUP1) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
EI24	SLC6A15	0.021	0.195	bioplex (SLC6A15) bioplex_WMM boldt youn_WMM boldt_WMM
HACD2	EI24	0.021	0.187	bioplex_WMM boldt gupta_WMM boldt_WMM
GPAT4	LPCAT1	0.02	0.187	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
HACD2	GPAT4	0.02	0.186	bioplex_WMM boldt gupta_WMM boldt_WMM
TMEM41B	SLC6A15	0.019	0.187	bioplex (SLC6A15) bioplex_WMM boldt youn_WMM boldt_WMM
HACD2	TRAM1	0.017	0.175	bioplex_WMM boldt boldt_WMM
HACD2	AUP1	0.017	0.163	bioplex_WMM boldt gupta_WMM boldt_WMM
GPAT4	TMEM161A	0.016	0.165	bioplex_WMM boldt gupta_WMM boldt_WMM
TRAM1	SLC6A15	0.015	0.142	bioplex (SLC6A15) bioplex_WMM boldt boldt_WMM
TMEM41B	EI24	0.015	0.14	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
UBE2G2	GPAT4	0.014	0.135	bioplex (GPAT4) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
SLC6A15	LPCAT1	0.014	0.139	bioplex (SLC6A15) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
TMEM41B	GPAT4	0.014	0.138	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
CHP1	TMEM161A	0.014	0.138	bioplex_WMM boldt gupta_WMM boldt_WMM
TMEM41B	TMEM161A	0.014	0.141	bioplex_WMM boldt gupta_WMM boldt_WMM
HACD2	CHP1	0.013	0.144	bioplex_WMM boldt gupta_WMM boldt_WMM
TMEM41B	AUP1	0.013	0.141	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
EI24	TMEM161A	0.013	0.149	bioplex_WMM boldt gupta_WMM boldt_WMM
TMEM41B	GPAT3	0.013	0.147	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
UBE2G2	SLC6A15	0.012	0.149	bioplex (SLC6A15) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
GPAT3	TMEM161A	0.011	0.141	bioplex_WMM boldt gupta_WMM boldt_WMM
HACD2	GPAT3	0.011	0.143	bioplex_WMM gupta_WMM WMM_only boldt_WMM
TMEM41B	CHP1	0.011	0.145	bioplex_WMM boldt youn_WMM boldt_WMM
SLC6A15	AUP1	0.01	0.132	bioplex (AUP1,SLC6A15) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
EI24	GPAT4	0.01	0.126	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
CHP1	LPCAT1	0.01	0.12	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
GPAT3	LPCAT1	0.01	0.121	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
GPAT3	AGPAT2	0.009	0.115	bioplex_WMM boldt boldt_WMM
HACD2	LPCAT1	0.009	0.103	bioplex_WMM boldt gupta_WMM boldt_WMM
HACD2	TLCD1	0.009	0.102	bioplex_WMM gupta_WMM WMM_only
UBE2G2	LPCAT1	0.009	0.108	bioplex_WMM boldt youn_WMM boldt_WMM
TMEM41B	LPCAT1	0.009	0.089	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
TMEM41B	TRAM1	0.009	0.09	bioplex_WMM boldt youn_WMM boldt_WMM
TRAM1	CHP1	0.008	0.089	bioplex_WMM boldt boldt_WMM
UBE2G2	AGPAT2	0.008	0.085	bioplex (AGPAT2) bioplex_WMM boldt boldt_WMM
TMEM41B	UBE2G2	0.008	0.09	bioplex (TMEM41B) bioplex_WMM boldt youn_WMM boldt_WMM
UBE2G2	CHP1	0.008	0.085	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
UBE2G2	TMEM161A	0.008	0.083	bioplex_WMM boldt gupta_WMM boldt_WMM
GPAT3	TLCD1	0.008	0.083	bioplex_WMM gupta_WMM WMM_only
GPAT4	TLCD1	0.008	0.085	bioplex_WMM gupta_WMM WMM_only
TRAM1	UBE2G2	0.008	0.086	bioplex_WMM boldt boldt_WMM
HACD2	UBE2G2	0.008	0.08	bioplex_WMM boldt gupta_WMM boldt_WMM
TMEM41B	TLCD1	0.008	0.06	bioplex_WMM gupta_WMM WMM_only
TEX2	TLCD1	0.008	0.04	bioplex_WMM WMM_only
TLCD1	LPCAT1	0.008	0.016	bioplex_WMM gupta_WMM WMM_only
AUP1	LPCAT1	0.007	0.01	bioplex (AUP1,LPCAT1) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
AUP1	TLCD1	0.007	0.009	bioplex_WMM gupta_WMM WMM_only
EI24	TLCD1	0.007	0.008	bioplex_WMM gupta_WMM WMM_only
TLCD1	TMEM161A	0.007	0.012	bioplex_WMM gupta_WMM WMM_only
TLCD1	AGPAT2	0.007	0.004	bioplex_WMM WMM_only
TRAM1	GPAT4	0.007	0.012	bioplex_WMM boldt boldt_WMM
UBE2G2	TEX2	0.007	0.006	bioplex_WMM youn_WMM gupta_WMM WMM_only
TEX2	AUP1	0.007	0.002	bioplex_WMM youn_WMM gupta_WMM WMM_only
TEX2	GPAT3	0.007	0.005	bioplex_WMM youn_WMM gupta_WMM WMM_only
TEX2	GPAT4	0.007	0.004	bioplex_WMM youn_WMM gupta_WMM WMM_only
AUP1	AGPAT2	0.007	0.001	bioplex_WMM boldt boldt_WMM
TEX2	CHP1	0.007	0.004	bioplex_WMM youn_WMM gupta_WMM WMM_only
UBE2G2	TLCD1	0.007	0.004	bioplex_WMM WMM_only
CHP1	TLCD1	0.007	0.004	bioplex_WMM WMM_only
EI24	CHP1	0.007	0.005	bioplex_WMM boldt youn_WMM boldt_WMM
HACD2	TEX2	0.007	0.005	bioplex_WMM gupta_WMM WMM_only
TMEM41B	TEX2	0.007	0.005	bioplex_WMM youn_WMM WMM_only
TEX2	LPCAT1	0.007	0.0	bioplex_WMM youn_WMM WMM_only
TRAM1	TLCD1	0.007	0.002	bioplex_WMM WMM_only
TEX2	TMEM161A	0.007	0.002	bioplex_WMM gupta_WMM WMM_only
TRAM1	TEX2	0.007	0.002	bioplex_WMM WMM_only
EI24	TEX2	0.007	0.001	bioplex_WMM youn_WMM WMM_only
TEX2	AGPAT2	0.007	0.002	bioplex_WMM WMM_only
HACD2	AGPAT2	0.007	0.004	bioplex_WMM WMM_only boldt_WMM
EI24	GPAT3	0.007	0.003	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
EI24	TRAM1	0.007	0.005	bioplex_WMM boldt boldt_WMM
EI24	LPCAT1	0.006	0.004	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
EI24	UBE2G2	0.006	0.003	bioplex_WMM boldt youn_WMM boldt_WMM
LPCAT1	AGPAT2	0.006	0.004	bioplex_WMM boldt boldt_WMM
TMEM41B	AGPAT2	0.006	0.008	bioplex_WMM WMM_only
UBE2G2	GPAT3	0.006	0.004	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
EI24	AUP1	0.006	0.003	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
TRAM1	GPAT3	0.006	0.006	bioplex_WMM boldt boldt_WMM
LPCAT1	TMEM161A	0.006	0.002	bioplex_WMM boldt boldt_WMM
AGPAT2	TMEM161A	0.006	0.006	bioplex_WMM boldt boldt_WMM
TRAM1	AGPAT2	0.006	0.01	bioplex_WMM boldt boldt_WMM
TRAM1	AUP1	0.005	0.008	bioplex (AUP1) bioplex_WMM boldt boldt_WMM
CHP1	AGPAT2	0.005	0.01	bioplex_WMM boldt boldt_WMM
GPAT4	AGPAT2	0.005	0.007	bioplex_WMM boldt boldt_WMM
TRAM1	LPCAT1	0.004	0.012	bioplex_WMM boldt youn_WMM boldt_WMM
EI24	AGPAT2	0.004	0.009	bioplex_WMM boldt boldt_WMM

Images

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Complex HuMAP2_05342 has an average edge precision of 0.11 which is ranked 6910 out of all 6965 complexes.

Related Complexes

Genename	Complexes
GPAT3	HuMAP2_03152 HuMAP2_05342
SLC6A15	HuMAP2_03152 HuMAP2_05342
GPAT4	HuMAP2_03152 HuMAP2_03641 HuMAP2_05342
TEX2	HuMAP2_03152 HuMAP2_04523 HuMAP2_05342
LPCAT1	HuMAP2_05342
TRAM1	HuMAP2_01976 HuMAP2_05342 HuMAP2_06873
EI24	HuMAP2_01441 HuMAP2_05342
CHP1	HuMAP2_03152 HuMAP2_03641 HuMAP2_05342
TMEM41B	HuMAP2_01441 HuMAP2_05342
HACD2	HuMAP2_01441 HuMAP2_03152 HuMAP2_05342
TMEM161A	HuMAP2_05342
TLCD1	HuMAP2_05342
UBE2G2	HuMAP2_02706 HuMAP2_05342 HuMAP2_06869
AUP1	HuMAP2_03152 HuMAP2_05342
AGPAT2	HuMAP2_05342

hu.MAP 2.0: Complex View

Search for a protein

Complex: HuMAP2_05342