hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05365
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HNRNPLL | Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) (Stromal RNA-regulating factor) | UniProt NCBI |
| DXO | Decapping and exoribonuclease protein (DXO) (EC 3.1.13.-) (EC 3.6.1.-) (Dom-3 homolog Z) | UniProt NCBI |
| CHURC1 | Protein Churchill | UniProt NCBI |
| ACTR3B | Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B) (Actin-related protein ARP4) | UniProt NCBI |
| ARPC2 | Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC) | UniProt NCBI |
| ESRP2 | Epithelial splicing regulatory protein 2 (RNA-binding motif protein 35B) (RNA-binding protein 35B) | UniProt NCBI |
| DIS3 | Exosome complex exonuclease RRP44 (EC 3.1.13.-) (EC 3.1.26.-) (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44) | UniProt NCBI |
| ARPC4 | Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC) | UniProt NCBI |
| ARPC5 | Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC) | UniProt NCBI |
| ACTR2 | Actin-related protein 2 (Actin-like protein 2) | UniProt NCBI |
| ACTR3 | Actin-related protein 3 (Actin-like protein 3) | UniProt NCBI |
| ARPC1B | Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC) | UniProt NCBI |
| ARPC3 | Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC) | UniProt NCBI |
| STXBP1 | Syntaxin-binding protein 1 (MUNC18-1) (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67) | UniProt NCBI |
| ARPC1A | Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) | UniProt NCBI |
| TBX3 | T-box transcription factor TBX3 (T-box protein 3) | UniProt NCBI |
| ARPC5L | Actin-related protein 2/3 complex subunit 5-like protein (Arp2/3 complex 16 kDa subunit 2) (ARC16-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0005885 | 1.22593028838e-23 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | Arp2/3 protein complex |
| CORUM:27 | 2.62488709844e-20 | 0.411764705882 | ACTR3 ARPC4 ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | Arp2/3 protein complex |
| GO:0034314 | 3.79908981289e-17 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | Arp2/3 complex-mediated actin nucleation |
| GO:0045010 | 2.44530192007e-16 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | actin nucleation |
| REAC:R-HSA-5663213 | 2.73460328886e-15 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | RHO GTPases Activate WASPs and WAVEs |
| REAC:R-HSA-3928662 | 7.13300468139e-15 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | EPHB-mediated forward signaling |
| GO:0030838 | 2.0730843266e-13 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | positive regulation of actin filament polymerization |
| REAC:R-HSA-2029482 | 2.54336308446e-13 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | Regulation of actin dynamics for phagocytic cup formation |
| REAC:R-HSA-2029480 | 3.28732673421e-12 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | Fcgamma receptor (FCGR) dependent phagocytosis |
| GO:0051015 | 4.13536692015e-12 | 0.588235294118 | ACTR3 ARPC4 ARPC1A ACTR3B ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | actin filament binding |
| REAC:R-HSA-2682334 | 5.99784648965e-12 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | EPH-Ephrin signaling |
| WP:WP2272 | 6.04130253608e-12 | 0.411764705882 | ARPC1A ARPC4 ARPC2 ARPC5 ARPC1B ARPC5L ARPC3 | Pathogenic Escherichia coli infection |
| GO:0032273 | 9.23387404908e-12 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | positive regulation of protein polymerization |
| KEGG:05131 | 2.01705066592e-11 | 0.411764705882 | ARPC1A ARPC4 ARPC2 ARPC5 ARPC1B ARPC5L ARPC3 | Shigellosis |
| GO:0030833 | 2.03147802914e-11 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of actin filament polymerization |
| KEGG:05132 | 2.81870349792e-11 | 0.411764705882 | ARPC1A ARPC4 ARPC2 ARPC5 ARPC1B ARPC5L ARPC3 | Salmonella infection |
| KEGG:05100 | 5.26238901946e-11 | 0.411764705882 | ARPC1A ARPC4 ARPC2 ARPC5 ARPC1B ARPC5L ARPC3 | Bacterial invasion of epithelial cells |
| GO:0008064 | 6.40758069218e-11 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of actin polymerization or depolymerization |
| GO:0030832 | 6.95869566189e-11 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of actin filament length |
| GO:0030041 | 1.03960962754e-10 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | actin filament polymerization |
| KEGG:04666 | 2.03228570824e-10 | 0.411764705882 | ARPC1A ARPC4 ARPC2 ARPC5 ARPC1B ARPC5L ARPC3 | Fc gamma R-mediated phagocytosis |
| GO:0002433 | 3.29969540662e-10 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis |
| GO:0038094 | 3.29969540662e-10 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | Fc-gamma receptor signaling pathway |
| GO:0038096 | 3.29969540662e-10 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | Fc-gamma receptor signaling pathway involved in phagocytosis |
| GO:0002431 | 4.11103852571e-10 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | Fc receptor mediated stimulatory signaling pathway |
| GO:0048013 | 4.11103852571e-10 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | ephrin receptor signaling pathway |
| GO:0008154 | 5.03757147827e-10 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | actin polymerization or depolymerization |
| GO:1902905 | 5.378420124e-10 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | positive regulation of supramolecular fiber organization |
| GO:0032271 | 6.95558472355e-10 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of protein polymerization |
| GO:0051495 | 1.44258584389e-09 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | positive regulation of cytoskeleton organization |
| GO:0003779 | 2.25231247855e-09 | 0.588235294118 | ACTR3 ARPC4 ARPC1A ACTR3B ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | actin binding |
| GO:0110053 | 3.15129471888e-09 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of actin filament organization |
| GO:0035861 | 5.95496451458e-09 | 0.411764705882 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC2 ARPC5 ARPC3 | site of double-strand break |
| GO:0031334 | 6.46022508361e-09 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | positive regulation of protein complex assembly |
| GO:0043254 | 1.24346942218e-08 | 0.588235294118 | ACTR3 ARPC4 ARPC1A STXBP1 ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of protein complex assembly |
| GO:0051258 | 1.43741843033e-08 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | protein polymerization |
| REAC:R-HSA-8856828 | 1.63235263202e-08 | 0.411764705882 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC2 ARPC5 ARPC3 | Clathrin-mediated endocytosis |
| GO:0032535 | 2.64050306274e-08 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of cellular component size |
| KEGG:05130 | 2.90850253452e-08 | 0.411764705882 | ARPC1A ARPC4 ARPC2 ARPC5 ARPC1B ARPC5L ARPC3 | Pathogenic Escherichia coli infection |
| KEGG:04810 | 4.27557735816e-08 | 0.411764705882 | ARPC1A ARPC4 ARPC2 ARPC5 ARPC1B ARPC5L ARPC3 | Regulation of actin cytoskeleton |
| GO:0090734 | 4.7308877285e-08 | 0.411764705882 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC2 ARPC5 ARPC3 | site of DNA damage |
| GO:0032956 | 5.66469029514e-08 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of actin cytoskeleton organization |
| GO:1902903 | 6.59835985979e-08 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of supramolecular fiber organization |
| GO:0032970 | 1.79270827206e-07 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of actin filament-based process |
| GO:0038093 | 1.84183373915e-07 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | Fc receptor signaling pathway |
| GO:0090066 | 1.85409270028e-07 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of anatomical structure size |
| KEGG:04144 | 1.86864567737e-07 | 0.411764705882 | ARPC1A ARPC4 ARPC2 ARPC5 ARPC1B ARPC5L ARPC3 | Endocytosis |
| REAC:R-HSA-195258 | 1.88408859715e-07 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | RHO GTPase Effectors |
| GO:0005200 | 2.14769324208e-07 | 0.411764705882 | ACTR3 ARPC4 ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | structural constituent of cytoskeleton |
| GO:0007015 | 3.65465348097e-07 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | actin filament organization |
| GO:0006909 | 6.95501688231e-07 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | phagocytosis |
| REAC:R-HSA-194315 | 2.54452113084e-06 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | Signaling by Rho GTPases |
| GO:0044089 | 2.8839016929e-06 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | positive regulation of cellular component biogenesis |
| GO:0051493 | 4.86541708634e-06 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of cytoskeleton organization |
| GO:0015629 | 4.97879887708e-06 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | actin cytoskeleton |
| REAC:R-HSA-422475 | 1.00821516065e-05 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | Axon guidance |
| GO:0002429 | 1.56864129901e-05 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | immune response-activating cell surface receptor signaling pathway |
| GO:0044087 | 2.03287275552e-05 | 0.588235294118 | ACTR3 ARPC4 ARPC1A STXBP1 ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of cellular component biogenesis |
| GO:0002768 | 2.7741769395e-05 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | immune response-regulating cell surface receptor signaling pathway |
| GO:0010638 | 2.84538775937e-05 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | positive regulation of organelle organization |
| GO:0008092 | 4.37493623633e-05 | 0.588235294118 | ACTR3 ARPC4 ARPC1A ACTR3B ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | cytoskeletal protein binding |
| GO:0030036 | 4.6559688728e-05 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | actin cytoskeleton organization |
| GO:0097435 | 4.73912861713e-05 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | supramolecular fiber organization |
| GO:0007169 | 5.94590785233e-05 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ESRP2 ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | transmembrane receptor protein tyrosine kinase signaling pathway |
| GO:0044877 | 9.82414961299e-05 | 0.588235294118 | ACTR3 ARPC4 ARPC1A ACTR3B ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | protein-containing complex binding |
| GO:0030029 | 0.000160049277529 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | actin filament-based process |
| GO:0034622 | 0.000229265362326 | 0.588235294118 | ACTR3 ARPC4 ARPC1A STXBP1 ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | cellular protein-containing complex assembly |
| GO:0002757 | 0.000307138359914 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | immune response-activating signal transduction |
| HPA:028010_23 | 0.000321331350066 | 0.352941176471 | ACTR3 ACTR2 ARPC2 ARPC1B HNRNPLL ARPC3 | lymph node; germinal center cells[Approved,High] |
| GO:0002764 | 0.000462137992357 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | immune response-regulating signaling pathway |
| REAC:R-HSA-199991 | 0.00053287022743 | 0.411764705882 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC2 ARPC5 ARPC3 | Membrane Trafficking |
| GO:0033043 | 0.000613021710404 | 0.588235294118 | ACTR3 ARPC4 ARPC1A STXBP1 ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | regulation of organelle organization |
| REAC:R-HSA-168249 | 0.000727899592967 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | Innate Immune System |
| REAC:R-HSA-5653656 | 0.000762112862965 | 0.411764705882 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC2 ARPC5 ARPC3 | Vesicle-mediated transport |
| REAC:R-HSA-1266738 | 0.000887726913858 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | Developmental Biology |
| GO:0002253 | 0.000952541023946 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | activation of immune response |
| GO:0007167 | 0.00104149657282 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ESRP2 ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | enzyme linked receptor protein signaling pathway |
| GO:0070358 | 0.00215539204286 | 0.176470588235 | ACTR3 ARPC3 ARPC2 | actin polymerization-dependent cell motility |
| HPA:028020_23 | 0.00280121157348 | 0.352941176471 | ACTR3 ACTR2 ARPC2 ARPC1B HNRNPLL ARPC3 | lymph node; non-germinal center cells[Approved,High] |
| GO:0005925 | 0.0031996213081 | 0.411764705882 | ACTR3 ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | focal adhesion |
| GO:0005924 | 0.00332546626468 | 0.411764705882 | ACTR3 ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | cell-substrate adherens junction |
| GO:0050778 | 0.00361647769894 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | positive regulation of immune response |
| GO:0030055 | 0.00365858065473 | 0.411764705882 | ACTR3 ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | cell-substrate junction |
| HPA:056020_23 | 0.00375070340949 | 0.352941176471 | ACTR3 ACTR2 ARPC2 ARPC1B HNRNPLL ARPC3 | tonsil; non-germinal center cells[Approved,High] |
| TF:M09606_1 | 0.00389888004696 | 0.647058823529 | ACTR3 ARPC4 CHURC1 ACTR2 ARPC5 ARPC2 ARPC1B DXO HNRNPLL ARPC3 ARPC5L | Factor: nerf; motif: NRRNSCGGAAGNRNNNN; match class: 1 |
| GO:0051130 | 0.00398468864237 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | positive regulation of cellular component organization |
| GO:0061024 | 0.00723489126061 | 0.470588235294 | ACTR3 ARPC4 ARPC1A STXBP1 ACTR2 ARPC5 ARPC2 ARPC3 | membrane organization |
| GO:0065008 | 0.00986725840364 | 0.764705882353 | ACTR3 ARPC4 ARPC1A STXBP1 ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L DXO DIS3 ARPC3 TBX3 | regulation of biological quality |
| KEGG:05135 | 0.0144978706555 | 0.176470588235 | ACTR3 ACTR2 ACTR3B | Yersinia infection |
| GO:0005912 | 0.0179507784484 | 0.411764705882 | ACTR3 ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | adherens junction |
| GO:0050776 | 0.0210204598065 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | regulation of immune response |
| GO:0070161 | 0.0210935289277 | 0.411764705882 | ACTR3 ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | anchoring junction |
| GO:0065003 | 0.0220262126297 | 0.588235294118 | ACTR3 ARPC4 ARPC1A STXBP1 ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | protein-containing complex assembly |
| GO:0002684 | 0.0236443673634 | 0.470588235294 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | positive regulation of immune system process |
| GO:0005198 | 0.0253954012654 | 0.411764705882 | ACTR3 ARPC4 ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | structural molecule activity |
| GO:0007010 | 0.0258051268418 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | cytoskeleton organization |
| KEGG:04530 | 0.0309257721559 | 0.176470588235 | ACTR3 ACTR2 ACTR3B | Tight junction |
| REAC:R-HSA-162582 | 0.0309291577062 | 0.529411764706 | ACTR3 ARPC4 ARPC1A ESRP2 ACTR2 ARPC5 ARPC2 ARPC1B ARPC3 | Signal Transduction |
| HPA:056010_23 | 0.0319517908606 | 0.294117647059 | ARPC3 ACTR3 ARPC2 ACTR2 ARPC1B | tonsil; germinal center cells[Approved,High] |
| TF:M01660_1 | 0.0333616793381 | 0.882352941176 | ACTR3 DIS3 ARPC4 ARPC1A STXBP1 ESRP2 ACTR2 ARPC5 ARPC2 ARPC1B DXO HNRNPLL CHURC1 ARPC3 ARPC5L | Factor: GABP-alpha; motif: CTTCCK; match class: 1 |
| HPA:056010_21 | 0.0351373480351 | 0.647058823529 | ACTR3 ARPC1A CHURC1 ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L HNRNPLL DIS3 ARPC3 | tonsil; germinal center cells[Approved,Low] |
| HPA:007030_22 | 0.0359257081197 | 0.470588235294 | ARPC1A ARPC3 ACTR2 ARPC5 ARPC5L HNRNPLL DIS3 ARPC2 | cerebellum; cells in molecular layer[Approved,Medium] |
| HPA:002020_21 | 0.0402678779736 | 0.588235294118 | ACTR3 ARPC1A ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L HNRNPLL DIS3 ARPC3 | appendix; lymphoid tissue[Approved,Low] |
| GO:0070062 | 0.0463870840784 | 0.647058823529 | ACTR3 ARPC4 ARPC1A STXBP1 ACTR3B ACTR2 ARPC5 ARPC2 ARPC1B ARPC5L ARPC3 | extracellular exosome |
| HPA:026010_21 | 0.0478874546797 | 0.529411764706 | ARPC1A ACTR3 CHURC1 ACTR2 ARPC5 ARPC5L HNRNPLL DIS3 ARPC2 | liver; bile duct cells[Approved,Low] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ACTR3 | ARPC3 | 1.0 | 0.949 | hein_WMM bioplex (ACTR3,ARPC3) bioplex_WMM boldt gupta_WMM fraction boldt_WMM |
| ACTR2 | ARPC2 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru hein (ACTR2) gupta_WMM fraction treiber_WMM |
| ACTR2 | ARPC1B | 1.0 | 0.949 | hein_WMM bioplex (ARPC1B) bioplex_WMM Guru hein (ACTR2) Malo fraction treiber_WMM |
| ARPC4 | ACTR3 | 1.0 | 0.949 | hein_WMM bioplex (ACTR3) bioplex_WMM boldt gupta_WMM fraction boldt_WMM |
| ACTR2 | ARPC3 | 1.0 | 0.949 | hein_WMM bioplex (ARPC3) bioplex_WMM Guru hein (ACTR2) gupta_WMM fraction |
| ACTR3 | ARPC2 | 1.0 | 0.949 | hein_WMM bioplex (ACTR3) bioplex_WMM gupta_WMM fraction |
| ARPC1B | ARPC2 | 1.0 | 0.949 | hein_WMM bioplex (ARPC1B) bioplex_WMM Guru fraction treiber_WMM |
| ACTR2 | ARPC4 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (ACTR2) gupta_WMM fraction treiber_WMM |
| ARPC5 | ARPC2 | 1.0 | 0.949 | hein_WMM bioplex (ARPC5) bioplex_WMM Guru fraction |
| ARPC3 | ARPC2 | 1.0 | 0.949 | hein_WMM bioplex (ARPC3) bioplex_WMM Guru gupta_WMM fraction treiber_WMM |
| ACTR2 | ARPC1A | 1.0 | 0.949 | hein_WMM bioplex (ARPC1A) bioplex_WMM Guru hein (ACTR2) gupta_WMM fraction |
| ARPC2 | ARPC1A | 1.0 | 0.949 | hein_WMM bioplex (ARPC1A) bioplex_WMM Guru gupta_WMM fraction treiber_WMM |
| ARPC4 | ARPC2 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru gupta_WMM fraction treiber_WMM |
| ARPC4 | ARPC1B | 1.0 | 0.949 | hein_WMM bioplex (ARPC1B) bioplex_WMM Guru fraction boldt_WMM treiber_WMM |
| ARPC3 | ARPC5L | 1.0 | 0.949 | hein_WMM bioplex (ARPC3) bioplex_WMM Guru fraction |
| ARPC4 | ARPC5 | 1.0 | 0.949 | hein_WMM bioplex (ARPC5) bioplex_WMM Guru fraction |
| ARPC5 | ACTR3 | 1.0 | 0.949 | hein_WMM bioplex (ACTR3,ARPC5) bioplex_WMM fraction |
| ACTR3 | ARPC1B | 1.0 | 0.949 | hein_WMM bioplex (ACTR3,ARPC1B) bioplex_WMM Malo fraction boldt_WMM treiber_WMM |
| ARPC5 | ARPC3 | 1.0 | 0.949 | hein_WMM bioplex (ARPC3,ARPC5) bioplex_WMM Guru fraction |
| ARPC4 | ARPC1A | 1.0 | 0.949 | hein_WMM bioplex (ARPC1A) bioplex_WMM Guru gupta_WMM fraction |
| ARPC5 | ARPC1B | 1.0 | 0.949 | hein_WMM bioplex (ARPC1B,ARPC5) bioplex_WMM Guru fraction |
| ARPC4 | ARPC3 | 1.0 | 0.949 | hein_WMM bioplex (ARPC3) bioplex_WMM Guru gupta_WMM fraction treiber_WMM |
| ACTR2 | ACTR3 | 1.0 | 0.949 | hein_WMM bioplex (ACTR3) bioplex_WMM hein (ACTR2) Malo gupta_WMM fraction treiber_WMM |
| ACTR3 | ARPC5L | 1.0 | 0.949 | hein_WMM bioplex (ACTR3) bioplex_WMM fraction |
| ARPC2 | ARPC5L | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru fraction |
| ARPC1B | ARPC5L | 1.0 | 0.949 | hein_WMM bioplex (ARPC1B) bioplex_WMM Guru fraction |
| ACTR3 | ARPC1A | 0.999 | 0.949 | hein_WMM bioplex (ACTR3,ARPC1A) bioplex_WMM gupta_WMM fraction |
| ARPC3 | ARPC1A | 0.999 | 0.949 | hein_WMM bioplex (ARPC1A,ARPC3) bioplex_WMM Guru gupta_WMM fraction |
| ACTR2 | ARPC5L | 0.999 | 0.946 | hein_WMM bioplex_WMM Guru hein (ACTR2) fraction |
| ARPC1B | ARPC3 | 0.999 | 0.945 | hein_WMM bioplex (ARPC1B,ARPC3) bioplex_WMM Guru fraction |
| ARPC5 | ARPC1A | 0.995 | 0.924 | hein_WMM bioplex (ARPC1A,ARPC5) bioplex_WMM Guru fraction |
| ARPC1A | ARPC5L | 0.995 | 0.924 | hein_WMM bioplex (ARPC1A) bioplex_WMM Guru fraction |
| ACTR2 | ARPC5 | 0.969 | 0.88 | hein_WMM bioplex (ARPC5) bioplex_WMM Guru hein (ACTR2) fraction |
| ARPC4 | ARPC5L | 0.962 | 0.87 | hein_WMM bioplex_WMM Guru fraction |
| ARPC1A | ACTR3B | 0.816 | 0.773 | bioplex (ACTR3B,ARPC1A) bioplex_WMM |
| HNRNPLL | ARPC2 | 0.744 | 0.74 | gupta_WMM fraction |
| ACTR2 | HNRNPLL | 0.686 | 0.712 | youn_WMM gupta_WMM fraction treiber_WMM |
| ARPC3 | ACTR3B | 0.659 | 0.696 | bioplex (ACTR3B,ARPC3) bioplex_WMM |
| HNRNPLL | ACTR3 | 0.507 | 0.627 | fraction treiber_WMM |
| ACTR3B | CHURC1 | 0.422 | 0.573 | bioplex (ACTR3B) bioplex_WMM |
| DIS3 | ACTR3 | 0.3 | 0.497 | bioplex_WMM youn_WMM gupta_WMM fraction |
| ARPC4 | ACTR3B | 0.298 | 0.498 | bioplex (ACTR3B) bioplex_WMM youn_WMM |
| HNRNPLL | ARPC4 | 0.276 | 0.487 | bioplex_WMM youn_WMM gupta_WMM fraction |
| HNRNPLL | TBX3 | 0.261 | 0.482 | bioplex (HNRNPLL) bioplex_WMM |
| ARPC5L | ACTR3B | 0.219 | 0.466 | bioplex (ACTR3B) bioplex_WMM |
| ARPC2 | ACTR3B | 0.178 | 0.438 | bioplex (ACTR3B) bioplex_WMM |
| ARPC1B | ACTR3B | 0.161 | 0.417 | bioplex (ACTR3B,ARPC1B) bioplex_WMM |
| DIS3 | ACTR2 | 0.13 | 0.399 | youn_WMM gupta_WMM fraction |
| ACTR2 | ACTR3B | 0.129 | 0.399 | bioplex (ACTR3B) bioplex_WMM youn_WMM |
| ARPC5 | ACTR3B | 0.095 | 0.359 | bioplex (ACTR3B,ARPC5) bioplex_WMM |
| STXBP1 | ARPC2 | 0.089 | 0.352 | fraction |
| HNRNPLL | ARPC3 | 0.083 | 0.351 | gupta_WMM fraction |
| ARPC3 | DXO | 0.078 | 0.352 | fraction |
| HNRNPLL | ARPC1A | 0.061 | 0.336 | bioplex_WMM fraction |
| STXBP1 | ACTR3 | 0.057 | 0.318 | fraction |
| DIS3 | ARPC2 | 0.056 | 0.312 | bioplex_WMM fraction |
| ESRP2 | HNRNPLL | 0.051 | 0.296 | bioplex (HNRNPLL) bioplex_WMM youn_WMM |
| DIS3 | ARPC4 | 0.045 | 0.287 | youn_WMM fraction |
| STXBP1 | ARPC1A | 0.044 | 0.279 | fraction |
| DIS3 | ARPC3 | 0.038 | 0.263 | bioplex_WMM fraction |
| ARPC3 | CHURC1 | 0.029 | 0.23 | hein_WMM bioplex (ARPC3) bioplex_WMM |
| ACTR3 | ACTR3B | 0.022 | 0.197 | bioplex (ACTR3,ACTR3B) bioplex_WMM |
| STXBP1 | ARPC3 | 0.019 | 0.182 | bioplex_WMM fraction |
| ARPC5 | ARPC5L | 0.014 | 0.141 | hein_WMM bioplex_WMM WMM_only |
| ACTR2 | CHURC1 | 0.013 | 0.143 | hein_WMM bioplex_WMM hein (ACTR2) |
| HNRNPLL | ARPC1B | 0.012 | 0.15 | bioplex_WMM fraction treiber_WMM |
| STXBP1 | ACTR2 | 0.011 | 0.145 | fraction treiber_WMM |
| ARPC2 | DXO | 0.011 | 0.132 | fraction |
| ARPC1A | CHURC1 | 0.011 | 0.145 | hein_WMM bioplex_WMM WMM_only |
| ARPC4 | CHURC1 | 0.01 | 0.121 | hein_WMM bioplex_WMM WMM_only |
| ARPC2 | CHURC1 | 0.01 | 0.115 | hein_WMM bioplex_WMM WMM_only |
| ARPC5 | CHURC1 | 0.01 | 0.101 | hein_WMM bioplex_WMM WMM_only |
| ARPC1B | CHURC1 | 0.01 | 0.098 | hein_WMM bioplex_WMM WMM_only |
| ACTR3 | CHURC1 | 0.009 | 0.113 | hein_WMM bioplex_WMM WMM_only |
| ARPC5L | CHURC1 | 0.009 | 0.107 | hein_WMM bioplex_WMM WMM_only |
| ESRP2 | TBX3 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| DIS3 | ARPC5 | 0.008 | 0.061 | fraction |
| DIS3 | HNRNPLL | 0.007 | 0.003 | youn_WMM WMM_only |
| ESRP2 | DXO | 0.007 | 0.002 | youn_WMM WMM_only |
| DIS3 | ESRP2 | 0.007 | 0.005 | youn_WMM WMM_only |
| ESRP2 | ARPC4 | 0.007 | 0.002 | youn_WMM WMM_only |
| DIS3 | ARPC5L | 0.007 | 0.003 | bioplex_WMM WMM_only |
| HNRNPLL | ACTR3B | 0.007 | 0.0 | youn_WMM WMM_only |
| DIS3 | DXO | 0.007 | 0.002 | youn_WMM WMM_only |
| ESRP2 | ACTR2 | 0.007 | 0.0 | youn_WMM WMM_only |
| STXBP1 | TBX3 | 0.007 | 0.005 | hein_WMM WMM_only |
| DIS3 | ARPC1A | 0.005 | 0.007 | bioplex_WMM fraction |
| ARPC1B | DXO | 0.004 | 0.011 | fraction |
| STXBP1 | ARPC5L | 0.004 | 0.012 | fraction |
| DIS3 | ARPC1B | 0.004 | 0.01 | bioplex_WMM fraction |
| HNRNPLL | ARPC5L | 0.004 | 0.008 | fraction |
| ACTR3 | DXO | 0.003 | 0.015 | fraction |
| DIS3 | ACTR3B | 0.003 | 0.015 | youn_WMM fraction |
| ARPC4 | DXO | 0.0 | 0.013 | fraction |
| ARPC5L | DXO | 0.0 | 0.011 | fraction |
| HNRNPLL | ARPC5 | 0.0 | 0.009 | fraction |
| STXBP1 | HNRNPLL | 0.0 | 0.009 | fraction |
| STXBP1 | ARPC4 | 0.0 | 0.008 | fraction |
| ARPC1B | ARPC1A | 0.0 | 0.01 | hein_WMM bioplex_WMM fraction |
| ACTR2 | DXO | 0.0 | 0.002 | fraction |
| ARPC5 | DXO | 0.0 | 0.001 | fraction |
| STXBP1 | ARPC1B | 0.0 | 0.002 | bioplex_WMM fraction |
| STXBP1 | ARPC5 | 0.0 | 0.002 | fraction |
Images
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Complex HuMAP2_05365 has an average edge precision of 0.449 which is ranked 2887 out of all 6965 complexes.
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