hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05375
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NME1 | Nucleoside diphosphate kinase A (NDK A) (NDP kinase A) (EC 2.7.4.6) (Granzyme A-activated DNase) (GAAD) (Metastasis inhibition factor nm23) (NM23-H1) (Tumor metastatic process-associated protein) | UniProt NCBI |
| IDI1 | Isopentenyl-diphosphate Delta-isomerase 1 (EC 5.3.3.2) (Isopentenyl pyrophosphate isomerase 1) (IPP isomerase 1) (IPPI1) | UniProt NCBI |
| CA2 | Carbonic anhydrase 2 (EC 4.2.1.1) (Carbonate dehydratase II) (Carbonic anhydrase C) (CAC) (Carbonic anhydrase II) (CA-II) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:01100 | 0.0105851300972 | 1.0 | NME1 IDI1 CA2 | Metabolic pathways |
| HP:0002653 | 0.0156055992881 | 0.666666666667 | CA2 NME1 | Bone pain |
| CORUM:758 | 0.0499776345577 | 0.333333333333 | NME1 | Prune/Nm23-H1 complex |
| CORUM:771 | 0.0499776345577 | 0.333333333333 | NME1 | NDPKA-AMPKalpha1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NME1 | IDI1 | 0.052 | 0.302 | bioplex (IDI1) bioplex_WMM youn_WMM gupta_WMM fraction |
| NME1 | CA2 | 0.028 | 0.232 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| CA2 | IDI1 | 0.007 | 0.005 | bioplex (IDI1) bioplex_WMM fraction |
Images
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Complex HuMAP2_05375 has an average edge precision of 0.18 which is ranked 6427 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NME1 | HuMAP2_01086 HuMAP2_02241 HuMAP2_04835 HuMAP2_05375 HuMAP2_06011 HuMAP2_06796 |
| IDI1 | HuMAP2_02241 HuMAP2_04579 HuMAP2_04835 HuMAP2_05375 HuMAP2_06011 |
| CA2 | HuMAP2_01086 HuMAP2_03513 HuMAP2_05375 HuMAP2_06011 HuMAP2_06796 |