hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05383
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GUCD1 | Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4) | UniProt NCBI |
| IMPAD1 | Inositol monophosphatase 3 (IMP 3) (IMPase 3) (EC 3.1.3.25) (EC 3.1.3.7) (Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase) (Golgi-resident PAP phosphatase) (gPAPP) (Inositol monophosphatase domain-containing protein 1) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3) | UniProt NCBI |
| PTCH1 | Protein patched homolog 1 (PTC) (PTC1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0010049 | 0.032187516076 | 0.666666666667 | IMPAD1 PTCH1 | Short metacarpal |
| KEGG:00920 | 0.0333280946102 | 0.333333333333 | IMPAD1 | Sulfur metabolism |
| HP:0005914 | 0.0393048254184 | 0.666666666667 | IMPAD1 PTCH1 | Aplasia/Hypoplasia involving the metacarpal bones |
| WP:WP3930 | 0.0499785733994 | 0.333333333333 | PTCH1 | EDA Signalling in Hair Follicle Development |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GUCD1 | PTCH1 | 0.031 | 0.241 | bioplex (PTCH1) bioplex_WMM |
| IMPAD1 | PTCH1 | 0.024 | 0.212 | bioplex (PTCH1) bioplex_WMM |
| GUCD1 | IMPAD1 | 0.007 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05383 has an average edge precision of 0.153 which is ranked 6687 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GUCD1 | HuMAP2_01933 HuMAP2_02658 HuMAP2_05383 HuMAP2_06174 |
| IMPAD1 | HuMAP2_05383 |
| PTCH1 | HuMAP2_05383 |