hu.MAP 2.0: Complex View

Human Protein Complex Map

Genename	Protein Name	Links
CALM2	Calmodulin-2	UniProt NCBI
ZBTB20	Zinc finger and BTB domain-containing protein 20 (Dendritic-derived BTB/POZ zinc finger protein) (Zinc finger protein 288)	UniProt NCBI
PPP1R9B	Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)	UniProt NCBI
SYNPO	Synaptopodin	UniProt NCBI
HMGB2	High mobility group protein B2 (High mobility group protein 2) (HMG-2)	UniProt NCBI
PLEKHG3	Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3)	UniProt NCBI
CALML3	Calmodulin-like protein 3 (CaM-like protein) (CLP) (Calmodulin-related protein NB-1)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:04744	0.0010389691246	0.285714285714	CALM2 CALML3	Phototransduction
KEGG:04924	0.0135196539521	0.285714285714	CALM2 CALML3	Renin secretion
KEGG:05133	0.0173383697329	0.285714285714	CALM2 CALML3	Pertussis
MIRNA:hsa-miR-5580-3p	0.0175313499747	0.428571428571	CALM2 ZBTB20 HMGB2	hsa-miR-5580-3p
KEGG:04971	0.01792209342	0.285714285714	CALM2 CALML3	Gastric acid secretion
KEGG:04720	0.0185153457906	0.285714285714	CALM2 CALML3	Long-term potentiation
KEGG:05031	0.0185153457906	0.285714285714	CALM2 CALML3	Amphetamine addiction
KEGG:05214	0.0222745983281	0.285714285714	CALM2 CALML3	Glioma
KEGG:04970	0.0263752467347	0.285714285714	CALM2 CALML3	Salivary secretion
WP:WP2059	0.0312748516465	0.285714285714	CALM2 CALML3	Alzheimers Disease
KEGG:04750	0.0315889561635	0.285714285714	CALM2 CALML3	Inflammatory mediator regulation of TRP channels
KEGG:04912	0.0315889561635	0.285714285714	CALM2 CALML3	GnRH signaling pathway
KEGG:04625	0.0372632222286	0.285714285714	CALM2 CALML3	C-type lectin receptor signaling pathway
KEGG:04713	0.0372632222286	0.285714285714	CALM2 CALML3	Circadian entrainment
KEGG:04925	0.0372632222286	0.285714285714	CALM2 CALML3	Aldosterone synthesis and secretion
KEGG:04916	0.0381112991793	0.285714285714	CALM2 CALML3	Melanogenesis
KEGG:04070	0.0407115897186	0.285714285714	CALM2 CALML3	Phosphatidylinositol signaling system
KEGG:04922	0.0443092098146	0.285714285714	CALM2 CALML3	Glucagon signaling pathway
KEGG:04270	0.0471051247715	0.285714285714	CALM2 CALML3	Vascular smooth muscle contraction

Protein 1	Protein 2	Score	Precision	Evidence
CALML3	CALM2	0.367	0.542	hein_WMM boldt hein (CALML3) boldt_WMM treiber_WMM
CALML3	SYNPO	0.142	0.406	hein_WMM hein (CALML3)
HMGB2	CALML3	0.05	0.297	hein_WMM bioplex_WMM hein (CALML3)
CALML3	11217	0.05	0.298	hein_WMM hein (CALML3)
CALML3	PPP1R9B	0.034	0.262	hein_WMM bioplex_WMM hein (CALML3)
CALML3	PLEKHG3	0.022	0.199	hein_WMM hein (CALML3)
CALML3	ZBTB20	0.021	0.186	hein_WMM hein (CALML3)
PLEKHG3	ZBTB20	0.008	0.082	hein_WMM WMM_only
PPP1R9B	ZBTB20	0.008	0.066	hein_WMM WMM_only
ZBTB20	CALM2	0.007	0.003	hein_WMM WMM_only
PPP1R9B	PLEKHG3	0.007	0.004	hein_WMM WMM_only
ZBTB20	11217	0.007	0.005	hein_WMM WMM_only
SYNPO	CALM2	0.007	0.007	hein_WMM WMM_only
HMGB2	ZBTB20	0.007	0.008	hein_WMM WMM_only
SYNPO	ZBTB20	0.007	0.002	hein_WMM WMM_only
11217	CALM2	0.006	0.002	hein_WMM youn_WMM gupta_WMM WMM_only
HMGB2	PPP1R9B	0.006	0.004	hein_WMM bioplex_WMM WMM_only
HMGB2	SYNPO	0.006	0.003	hein_WMM WMM_only
PLEKHG3	CALM2	0.006	0.006	hein_WMM WMM_only
PPP1R9B	CALM2	0.006	0.007	hein_WMM gupta_WMM WMM_only
HMGB2	CALM2	0.006	0.006	hein_WMM gupta_WMM WMM_only
HMGB2	PLEKHG3	0.006	0.003	hein_WMM WMM_only
SYNPO	PPP1R9B	0.006	0.003	hein_WMM WMM_only
PPP1R9B	11217	0.006	0.004	hein_WMM WMM_only
SYNPO	11217	0.006	0.009	hein_WMM WMM_only
PLEKHG3	11217	0.006	0.008	hein_WMM WMM_only
SYNPO	PLEKHG3	0.006	0.011	hein_WMM WMM_only
HMGB2	11217	0.005	0.012	hein_WMM WMM_only

Click to enlarge

Complex HuMAP2_05394 has an average edge precision of 0.087 which is ranked 6956 out of all 6965 complexes.

Genename	Complexes
CALM2	HuMAP2_05394
ZBTB20	HuMAP2_05394
PPP1R9B	HuMAP2_04615 HuMAP2_05328 HuMAP2_05394 HuMAP2_06738
SYNPO	HuMAP2_02178 HuMAP2_03582 HuMAP2_04615 HuMAP2_05394 HuMAP2_05638
HMGB2	HuMAP2_00876 HuMAP2_03246 HuMAP2_05394 HuMAP2_05836 HuMAP2_06704
PLEKHG3	HuMAP2_04615 HuMAP2_05394
CALML3	HuMAP2_02160 HuMAP2_02789 HuMAP2_05394 HuMAP2_06706