hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05395
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ARF4 | ADP-ribosylation factor 4 | UniProt NCBI |
| COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial (3-demethylubiquinol 3-O-methyltransferase) (EC 2.1.1.64) (Polyprenyldihydroxybenzoate methyltransferase) (EC 2.1.1.114) | UniProt NCBI |
| ARF1 | ADP-ribosylation factor 1 | UniProt NCBI |
| ARF5 | ADP-ribosylation factor 5 | UniProt NCBI |
| ARL1 | ADP-ribosylation factor-like protein 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6811442 | 2.19965655263e-05 | 0.8 | ARF5 ARL1 ARF4 ARF1 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| CORUM:7483 | 4.0241279111e-05 | 0.4 | ARF1 ARL1 | ARF1-ARL1-PKD2-ARFIP2 complex |
| REAC:R-HSA-6811434 | 0.000384877154433 | 0.6 | ARF5 ARF4 ARF1 | COPI-dependent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-6807878 | 0.000397120285508 | 0.6 | ARF5 ARF4 ARF1 | COPI-mediated anterograde transport |
| REAC:R-HSA-8856688 | 0.000960389260783 | 0.6 | ARF5 ARF4 ARF1 | Golgi-to-ER retrograde transport |
| REAC:R-HSA-199977 | 0.00130639580421 | 0.6 | ARF5 ARF4 ARF1 | ER to Golgi Anterograde Transport |
| REAC:R-HSA-199991 | 0.00166286547268 | 0.8 | ARF5 ARL1 ARF4 ARF1 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.0020580612036 | 0.8 | ARF5 ARL1 ARF4 ARF1 | Vesicle-mediated transport |
| REAC:R-HSA-948021 | 0.00211299613483 | 0.6 | ARF5 ARF4 ARF1 | Transport to the Golgi and subsequent modification |
| GO:0005525 | 0.00415715596103 | 0.8 | ARF5 ARL1 ARF4 ARF1 | GTP binding |
| GO:0032549 | 0.00558300460276 | 0.8 | ARF5 ARL1 ARF4 ARF1 | ribonucleoside binding |
| GO:0032550 | 0.00558300460276 | 0.8 | ARF5 ARL1 ARF4 ARF1 | purine ribonucleoside binding |
| GO:0001883 | 0.00570607633709 | 0.8 | ARF5 ARL1 ARF4 ARF1 | purine nucleoside binding |
| GO:0001882 | 0.00608750012464 | 0.8 | ARF5 ARL1 ARF4 ARF1 | nucleoside binding |
| GO:0032561 | 0.00705155239441 | 0.8 | ARF5 ARL1 ARF4 ARF1 | guanyl ribonucleotide binding |
| GO:0019001 | 0.00719806897192 | 0.8 | ARF5 ARL1 ARF4 ARF1 | guanyl nucleotide binding |
| REAC:R-HSA-446203 | 0.0100880466408 | 0.6 | ARF5 ARF4 ARF1 | Asparagine N-linked glycosylation |
| GO:0003924 | 0.0179259894308 | 0.8 | ARF5 ARL1 ARF4 ARF1 | GTPase activity |
| GO:0031584 | 0.0270421395626 | 0.4 | ARF4 ARL1 | activation of phospholipase D activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ARF1 | ARF4 | 0.201 | 0.451 | Guru gupta_WMM fraction boldt_WMM |
| COQ3 | ARF4 | 0.117 | 0.391 | fraction |
| ARF5 | COQ3 | 0.092 | 0.355 | fraction |
| ARF4 | ARL1 | 0.053 | 0.301 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| ARF5 | ARF1 | 0.05 | 0.298 | Guru gupta_WMM fraction |
| ARF5 | ARF4 | 0.006 | 0.006 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| ARF5 | ARL1 | 0.005 | 0.012 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| ARF1 | ARL1 | 0.0 | 0.006 | Guru boldt gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_05395 has an average edge precision of 0.228 which is ranked 5739 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ARF4 | HuMAP2_05395 HuMAP2_05489 |
| COQ3 | HuMAP2_02118 HuMAP2_05395 HuMAP2_05984 |
| ARF1 | HuMAP2_03431 HuMAP2_05395 |
| ARF5 | HuMAP2_00244 HuMAP2_02118 HuMAP2_03431 HuMAP2_05395 |
| ARL1 | HuMAP2_05395 HuMAP2_05489 |