hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05396
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CTSS | Cathepsin S (EC 3.4.22.27) | UniProt NCBI |
| IRF2 | Interferon regulatory factor 2 (IRF-2) | UniProt NCBI |
| CYP4F22 | Cytochrome P450 4F22 (EC 1.14.14.-) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5579005 | 0.0498572752401 | 0.333333333333 | CYP4F22 | Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CTSS | IRF2 | 0.595 | 0.666 | bioplex (IRF2) bioplex_WMM |
| IRF2 | CYP4F22 | 0.034 | 0.259 | bioplex (IRF2) bioplex_WMM |
| CTSS | CYP4F22 | 0.008 | 0.091 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05396 has an average edge precision of 0.339 which is ranked 4139 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CTSS | HuMAP2_02214 HuMAP2_05396 |
| IRF2 | HuMAP2_02214 HuMAP2_05396 |
| CYP4F22 | HuMAP2_03014 HuMAP2_05396 |